SINGLE-VENTRICLE
Clinical trials for SINGLE-VENTRICLE explained in plain language.
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Could a child's own stem cells strengthen a weak heart after surgery?
Disease control Recruiting nowThis study tests whether injecting a child's own heart stem cells (JRM-001) after reconstructive surgery can improve heart function in children with single ventricle heart defects. About 40 children scheduled for Glenn or Fontan surgery will receive either the stem cells or a pla…
Matched conditions: SINGLE-VENTRICLE
Phase: PHASE3 • Sponsor: Metcela Inc. • Aim: Disease control
Last updated Jun 15, 2026 19:07 UTC
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Special baby formula may boost growth in heart defect infants
Disease control Recruiting nowThis study tests whether a high-calorie formula called Fortini helps babies born with a serious heart condition (single ventricle) grow better after their first heart surgery. About 100 infants will be randomly assigned to receive either Fortini or standard high-calorie formula a…
Matched conditions: SINGLE-VENTRICLE
Phase: NA • Sponsor: Driscoll Children's Hospital • Aim: Disease control
Last updated Jun 11, 2026 12:09 UTC
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Digital fitness boost for kids with rare heart condition
Disease control Recruiting nowThis study tests whether a home-based digital exercise program can increase physical activity and fitness in children aged 10-17 with Fontan circulation, a heart condition. Participants will wear an activity tracker for 12 months and complete fitness tests. The goal is to see if …
Matched conditions: SINGLE-VENTRICLE
Phase: NA • Sponsor: Children's Hospital of Philadelphia • Aim: Disease control
Last updated Jun 09, 2026 12:06 UTC
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Heart rehab trial aims to boost steps and quality of life in fontan failure
Symptom relief Recruiting nowThis study tests whether a cardiac rehabilitation program can help adults with Fontan failure (a type of heart failure from a birth defect) walk more each day and feel less frail. About 50 participants will either join the rehab program or receive usual care. The goal is to see i…
Matched conditions: SINGLE-VENTRICLE
Phase: NA • Sponsor: Stanford University • Aim: Symptom relief
Last updated Jun 15, 2026 18:54 UTC
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New registry tracks heart drug use in adults born with heart defects
Knowledge-focused Recruiting nowThis study is a registry that collects information from 400 adults with congenital heart disease who are taking a class of drugs called SGLT2 inhibitors. Researchers want to understand how these drugs are prescribed, how safe and tolerable they are, and whether they help with hea…
Matched conditions: SINGLE-VENTRICLE
Sponsor: Leiden University Medical Center • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:06 UTC
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New 3D heart scan could improve care for kids with one ventricle
Knowledge-focused Recruiting nowThis study is testing a new 3D ultrasound technique to measure heart size and function in children and young adults born with only one working heart chamber (single ventricle). Researchers will compare the new method to standard tests like echocardiograms and cardiac MRIs. The go…
Matched conditions: SINGLE-VENTRICLE
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:02 UTC
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Tiny hearts, big clues: new study probes clot dangers in newborns
Knowledge-focused Recruiting nowThis study aims to understand why newborns with severe congenital heart disease are more likely to develop dangerous blood clots after heart surgery. Researchers will collect blood samples from 10 babies to look at tiny molecules called microRNAs that may control clotting. The go…
Matched conditions: SINGLE-VENTRICLE
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated Jun 12, 2026 12:08 UTC
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Infant heart drug under the microscope: new study aims to unlock Digoxin's secrets
Knowledge-focused Recruiting nowThis study looks at how the heart medication digoxin is processed by the bodies of infants born with a single lower heart chamber. Researchers will collect blood samples from 20 babies already prescribed digoxin as part of their routine care. The goal is to learn more about the d…
Matched conditions: SINGLE-VENTRICLE
Phase: PHASE1, PHASE2 • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 01, 2026 17:56 UTC