SINGLE-VENTRICLE
Clinical trials for SINGLE-VENTRICLE explained in plain language.
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Digital fitness boost for kids with rare heart condition
Disease control Recruiting nowThis study tests whether a home-based digital exercise program can increase physical activity and fitness in children aged 10-17 with Fontan circulation, a heart condition from single-ventricle defects. Two hundred participants will wear activity trackers for 12 months and be ran…
Matched conditions: SINGLE-VENTRICLE
Phase: NA • Sponsor: Children's Hospital of Philadelphia • Aim: Disease control
Last updated May 26, 2026 04:05 UTC
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Special baby formula may help heart defect infants gain weight and avoid hospital readmissions
Disease control Recruiting nowThis study tests whether a high-calorie, easy-to-digest formula called Fortini helps babies born with a serious heart condition (single ventricle) grow better after their first heart surgery. About 100 infants will be randomly assigned to receive either Fortini or standard high-c…
Matched conditions: SINGLE-VENTRICLE
Phase: NA • Sponsor: Driscoll Children's Hospital • Aim: Disease control
Last updated May 26, 2026 03:57 UTC
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Kids' own stem cells may boost heart function after major surgery
Disease control Recruiting nowThis study tests whether injecting a child's own heart stem cells (JRM-001) during a second or third heart surgery can improve heart pumping strength. It involves 40 children with single ventricle heart defects who have heart failure. The goal is to see if this cell therapy helps…
Matched conditions: SINGLE-VENTRICLE
Phase: PHASE3 • Sponsor: Metcela Inc. • Aim: Disease control
Last updated May 20, 2026 11:57 UTC
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Heart rehab trial aims to boost daily steps in fontan failure patients
Symptom relief Recruiting nowThis study tests whether a cardiac rehabilitation program can help adults with Fontan failure walk more each day and improve their exercise ability and quality of life. About 50 participants will either join the rehab program or receive usual care. The goal is to see if structure…
Matched conditions: SINGLE-VENTRICLE
Phase: NA • Sponsor: Stanford University • Aim: Symptom relief
Last updated May 19, 2026 11:49 UTC
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New 3D heart scan could improve care for kids born with one ventricle
Knowledge-focused Recruiting nowThis study is testing a new 3D ultrasound technique to see if it can accurately measure heart size and pumping ability in children and young adults born with a single ventricle (one pumping chamber). About 100 participants will get a standard heart ultrasound and/or MRI, and the …
Matched conditions: SINGLE-VENTRICLE
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated May 26, 2026 04:02 UTC
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Tiny blood samples, big clues: new study aims to unravel clot risks in newborn heart patients
Knowledge-focused Recruiting nowThis study looks at why newborns with severe congenital heart disease are more likely to develop dangerous blood clots after heart surgery. Researchers will collect blood samples from 10 babies to study tiny molecules called microRNAs that control inflammation and clotting. The g…
Matched conditions: SINGLE-VENTRICLE
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated May 26, 2026 03:58 UTC
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Infant heart drug under the microscope: new study seeks answers
Knowledge-focused Recruiting nowThis study looks at how the heart medication digoxin is processed by infants born with a single ventricle heart defect. Researchers will collect blood samples from 20 babies under 6 months old, either during routine care or through extra draws, to measure drug levels and heart fu…
Matched conditions: SINGLE-VENTRICLE
Phase: PHASE1, PHASE2 • Sponsor: Duke University • Aim: Knowledge-focused
Last updated May 26, 2026 03:58 UTC
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Diabetes drug under review for heart defect patients
Knowledge-focused Recruiting nowThis study is collecting information from 400 adults with congenital heart disease who are taking a type of diabetes drug called SGLT2 inhibitors. Researchers want to see how doctors prescribe these drugs, whether they cause side effects, and if they help with heart failure sympt…
Matched conditions: SINGLE-VENTRICLE
Sponsor: Leiden University Medical Center • Aim: Knowledge-focused
Last updated May 26, 2026 03:52 UTC