SINGLE-VENTRICLE
Clinical trials for SINGLE-VENTRICLE explained in plain language.
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Groundbreaking trial tests Child's own stem cells to strengthen tiny hearts
Disease control Recruiting nowThis study is testing whether injecting a child's own heart stem cells directly into their heart arteries after major reconstructive surgery can help improve their heart's pumping strength and overall function. It involves 40 children born with severe heart defects where only one…
Matched conditions: SINGLE-VENTRICLE
Phase: PHASE3 • Sponsor: Metcela Inc. • Aim: Disease control
Last updated Mar 23, 2026 15:29 UTC
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New heart scan could improve care for complex congenital defects
Diagnosis Recruiting nowThis study is testing a new 3D ultrasound method to measure heart size and function in children and young adults born with a single working heart ventricle. Researchers want to see if this new imaging technique works as well as the current gold standard, cardiac MRI. The goal is …
Matched conditions: SINGLE-VENTRICLE
Phase: NA • Sponsor: Duke University • Aim: Diagnosis
Last updated Apr 03, 2026 14:43 UTC
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Can exercise rehab help failing fontan hearts?
Symptom relief Recruiting nowThis study aims to see if a supervised cardiac rehabilitation program can help adults living with Fontan heart failure. Researchers will compare the rehab program to usual medical care in 50 participants. They will measure if rehab improves daily activity, exercise tolerance, str…
Matched conditions: SINGLE-VENTRICLE
Phase: NA • Sponsor: Stanford University • Aim: Symptom relief
Last updated Apr 02, 2026 14:57 UTC
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Researchers track heart drug in tiniest patients
Knowledge-focused Recruiting nowThis study aims to learn how infants with a serious heart defect called single ventricle disease process the medication digoxin, which is already given to help their heart function. Researchers will collect small blood samples from up to 20 infants during their regular medical ca…
Matched conditions: SINGLE-VENTRICLE
Phase: PHASE1, PHASE2 • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:42 UTC
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Scientists search for clues to stop deadly clots in fragile newborn hearts
Knowledge-focused Recruiting nowThis study aims to understand why newborns with severe congenital heart disease are at high risk for dangerous blood clots after surgery. Researchers will collect blood samples from 10 newborns to analyze tiny molecules that may control clotting. The goal is to uncover the biolog…
Matched conditions: SINGLE-VENTRICLE
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Global watchdog launched for promising heart drug in rare patient group
Knowledge-focused Recruiting nowThis international registry aims to gather real-world information on how a class of drugs called SGLT2 inhibitors is being used in adults born with heart defects. It will track 400 patients who are already prescribed this medication to see how they tolerate it and if it helps imp…
Matched conditions: SINGLE-VENTRICLE
Sponsor: Leiden University Medical Center • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC