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Which cancer care model boosts quality of life? large trial seeks answers

NCT ID NCT05297734

First seen May 04, 2026 · Last updated Jun 19, 2026 · Updated 8 times

Summary

This study compares two approaches to supportive cancer care for nearly 3,000 adults with cancer. One group gets information through email or their health record, while the other works one-on-one with a lay health worker over 12 months. The goal is to see which model better improves quality of life and helps with advance care planning.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beckman Research Institute of City of Hope

    RECRUITING

    Duarte, California, 91010, United States

    Contact Phone: •••-•••-••••

  • George E. Wahlen Department of Veterans Affairs Medical Center

    RECRUITING

    Salt Lake City, Utah, 84148, United States

  • Kaiser Foundation Research Institute

    RECRUITING

    San Francisco, California, 94115, United States

    Contact

  • North Las Vegas VA Medical Center

    ACTIVE_NOT_RECRUITING

    Las Vegas, Nevada, 89086, United States

  • Oncology Institute for Hope and Innovation

    RECRUITING

    Los Angeles, California, 90017, United States

    Contact

  • Pacific Cancer Care

    ACTIVE_NOT_RECRUITING

    Monterey, California, 93940, United States

  • Sacramento VA Medical Center - VA Northern California Health Care System

    ACTIVE_NOT_RECRUITING

    Mather, California, 95655, United States

  • San Francisco VA Medical Center

    ACTIVE_NOT_RECRUITING

    San Francisco, California, 94121, United States

  • Santa Clara Valley Medical Center

    RECRUITING

    Fruitdale, California, 95128, United States

    Contact

  • Spark M. Matsunaga VA Medical Center

    RECRUITING

    Honolulu, Hawaii, 96819, United States

  • St Jude Heritage Medical Group

    RECRUITING

    Fullerton, California, 92835, United States

    Contact

  • University of Alabama at Birmingham

    RECRUITING

    Birmingham, Alabama, 35294, United States

    Contact

  • University of San Francisco

    RECRUITING

    San Francisco, California, 94117, United States

    Contact

  • University of South Alabama

    RECRUITING

    Mobile, Alabama, 36688, United States

    Contact

  • VA Medical Center, Fresno

    RECRUITING

    Fresno, California, 93703, United States

  • VA Palo Alto

    ACTIVE_NOT_RECRUITING

    Palo Alto, California, 94305, United States

  • Zuckerberg San Francisco General

    RECRUITING

    San Francisco, California, 94110, United States

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Supportive cancer care models (technology-based vs. team-based with lay health workers)

What this could lead to

If successful, this could show which care model better helps cancer patients manage symptoms and plan future care, improving their quality of life.

What could go wrong

This is a comparative effectiveness trial, not testing a new drug or cure. The results may show only small differences between the two approaches, and benefits may vary by patient.

Conditions

The condition(s) this trial relates to.

breast neoplasm bronchogenic carcinoma carcinoma Carcinoma, Ovarian Epithelial colonic neoplasm Death Disease Progression epithelial neoplasm Esophageal Neoplasms gastric neoplasm glioblastoma lung disorder lung neoplasm melanoma Myelodysplastic Syndromes neoplasm Neoplasms by Histologic Type Neoplasms by Site non-small cell lung carcinoma osteosarcoma ovarian cancer pancreatic neoplasm rectal neoplasm renal cell carcinoma respiratory system disorder respiratory tract neoplasm sarcoma skin neoplasm small cell lung carcinoma Thoracic Neoplasms Urogenital Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.