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Which cancer care model boosts quality of life? large trial seeks answers

NCT ID NCT05297734

Symptom relief Sponsor: Stanford University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two approaches to supportive cancer care for nearly 3,000 adults with cancer. One group gets information through email or their health record, while the other works one-on-one with a lay health worker over 12 months. The goal is to see which model better improves quality of life and helps with advance care planning.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Supportive cancer care models (technology-based vs. team-based with lay health workers)
What this could lead to
If successful, this could show which care model better helps cancer patients manage symptoms and plan future care, improving their quality of life.
What could go wrong
This is a comparative effectiveness trial, not testing a new drug or cure. The results may show only small differences between the two approaches, and benefits may vary by patient.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 2,996 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2022

Expected to finish

Feb 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Newly diagnosed patients with solid tumor cancer diagnosis or recurrence of the disease. 2. Patients must have the ability to understand and willingness to provide verbal consent. 3. Participants must speak English, Spanish, Chinese, or Vietnamese. Exclusion Criteria: 1. Inability to consent to the study 2. Plans to change oncologist within 12 months 3. Employed by the practice site 4. Patients who anticipate moving from the area within 12 months

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Conditions

The condition(s) this trial relates to.

breast neoplasm bronchogenic carcinoma cancer carcinoma Carcinoma, Ovarian Epithelial colonic neoplasm Death Disease Progression epithelial neoplasm Esophageal Neoplasms gastric neoplasm glioblastoma lung disorder lung neoplasm melanoma Myelodysplastic Syndromes neoplasm Neoplasms by Histologic Type Neoplasms by Site non-small cell lung carcinoma osteosarcoma ovarian cancer pancreatic neoplasm rectal neoplasm renal cell carcinoma respiratory system disorder respiratory tract neoplasm sarcoma skin neoplasm small cell lung carcinoma Thoracic Neoplasms Urogenital Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cancer End of life

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    12 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Beckman Research Institute of City of Hope

    RECRUITING

    Duarte, California, 91010, United States

  • George E. Wahlen Department of Veterans Affairs Medical Center

    RECRUITING

    Salt Lake City, Utah, 84148, United States

  • Kaiser Foundation Research Institute

    RECRUITING

    San Francisco, California, 94115, United States

  • North Las Vegas VA Medical Center

    ACTIVE_NOT_RECRUITING

    Las Vegas, Nevada, 89086, United States

  • Oncology Institute for Hope and Innovation

    RECRUITING

    Los Angeles, California, 90017, United States

  • Pacific Cancer Care

    ACTIVE_NOT_RECRUITING

    Monterey, California, 93940, United States

  • Sacramento VA Medical Center - VA Northern California Health Care System

    ACTIVE_NOT_RECRUITING

    Mather, California, 95655, United States

  • San Francisco VA Medical Center

    ACTIVE_NOT_RECRUITING

    San Francisco, California, 94121, United States

  • Santa Clara Valley Medical Center

    RECRUITING

    Fruitdale, California, 95128, United States

  • Spark M. Matsunaga VA Medical Center

    RECRUITING

    Honolulu, Hawaii, 96819, United States

  • St Jude Heritage Medical Group

    RECRUITING

    Fullerton, California, 92835, United States

  • University of Alabama at Birmingham

    RECRUITING

    Birmingham, Alabama, 35294, United States

  • University of San Francisco

    RECRUITING

    San Francisco, California, 94117, United States

  • University of South Alabama

    RECRUITING

    Mobile, Alabama, 36688, United States

  • VA Medical Center, Fresno

    RECRUITING

    Fresno, California, 93703, United States

  • VA Palo Alto

    ACTIVE_NOT_RECRUITING

    Palo Alto, California, 94305, United States

  • Zuckerberg San Francisco General

    RECRUITING

    San Francisco, California, 94110, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.