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New cell therapy aims to make mismatched donor transplants safer for blood cancer patients

NCT ID NCT06551584

First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 31 times

Summary

This early-stage trial tests a cell therapy called Orca-T combined with standard drugs to prevent graft-versus-host disease (GVHD) in up to 24 adults with advanced blood cancers like leukemia or MDS. Participants receive a stem cell transplant from a donor who is only a 7 out of 8 HLA match. The main goal is to see if this approach reduces severe transplant-related complications within the first 100 days.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Stanford University

    RECRUITING

    Palo Alto, California, 94304, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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