National Taiwan University Hospital

This study compares two seasonal flu vaccines—one with an extra ingredient to boost the immune response (adjuvanted) and one without—in 200 adults aged 65 and older who also have chronic medical conditions like diabetes or heart disease. The goal is to see which vaccine triggers …

This study tests a treatment for advanced liver cancer that delivers chemotherapy directly to the liver through a thin tube, combined with a gentle embolization agent (lipiodol) to block tumor blood supply temporarily. The goal is to shrink tumors while keeping the liver working …

This study tests whether combining two osteoporosis drugs (romosozumab and denosumab) works better than either drug alone for postmenopausal women with weak bones. 90 women will receive one of three treatments for 6 months. The goal is to see if the combination improves bone dens…

This study tests whether a wearable device and AI app can help obese adults lose more weight than standard diet and exercise alone. About 120 participants will follow a 6-month program with coaching and health tracking. The goal is to see if technology boosts weight loss and impr…

This study tests if valacyclovir works as well as valganciclovir to prevent CMV and EBV infections in 80 kidney transplant patients. Valganciclovir can cause bone marrow problems, so researchers want to see if valacyclovir is a safer option. Participants will be randomly assigned…

This study tests two different ways of giving two osteoporosis drugs (romosozumab and denosumab) over two years. One group gets a repeating 6-month cycle of each drug, while the other gets 12 months of one drug followed by 12 months of the other. The goal is to see which schedule…

This study looks at a new way to stop taking the osteoporosis drug denosumab (Prolia) without losing bone density. When people stop denosumab after using it for years, their bones can weaken quickly. The standard approach of switching to another drug often doesn't fully prevent t…

This study tests whether hydroxychloroquine, a drug used for malaria and arthritis, can improve fatty liver disease with inflammation. About 210 adults will take either a low or high dose of the drug or a placebo daily for a year. Researchers will check liver health and side effe…

This study tests whether SGLT2 inhibitors, drugs already used for diabetes and chronic kidney disease, can help people with acute kidney disease (AKD). AKD occurs after a sudden kidney injury and can lead to permanent kidney damage. The trial will include 264 adults with AKD, wit…

This study compares proton therapy to standard photon therapy for cervical cancer patients needing extended-field radiation. The goal is to see if proton therapy causes less severe lymphopenia (low white blood cell count) and improves survival and side effects. About 44 adults wi…

This study tests whether adding bismuth to a 14-day stomach-acid-blocker-and-antibiotic treatment works better for wiping out H. pylori bacteria in adults who haven't been treated before. About 990 participants will be randomly assigned to get the dual therapy with or without bis…

This study tests if a preserved donor aortic patch can safely repair holes or defects in the windpipe or bronchial tubes. Ten people with severe airway problems from birth or injury will receive the patch. The main goal is to see if patients survive 90 days after surgery without …

This study tests whether adding doxycycline to the standard penicillin shot works better for treating early syphilis in people with HIV. About 688 adults with HIV and early syphilis will be randomly assigned to get either penicillin alone or penicillin plus a 7-day course of doxy…

This study tests a new approach for people with a type of esophageal cancer that has spread locally but not to distant organs. Participants receive a combination of immunotherapy and chemotherapy, followed by chemoradiation, and then surgery. The goal is to see if this sequence c…

This study tests whether giving a combination of three drugs (epinephrine, vasopressin, and a steroid) to adults who suffer a sudden cardiac arrest outside the hospital can restart their heart better than the standard single drug (epinephrine). About 1,344 participants will be ra…

This study looks at whether adding core muscle exercises (like Pilates) to standard cardiac rehab helps people with heart failure or a recent heart attack recover better. Sixty adults will be split into three groups: core training only, aerobic exercise only, or both combined. Th…

This study looks at whether using a 10% benzoyl peroxide acne cleanser on the skin before shoulder surgery can reduce harmful bacteria. About 150 people having rotator cuff repair will be randomly assigned to either standard soap or the acne wash. The goal is to see if this simpl…

This study aims to help 200 adults aged 50 and older in a rural area who have had a hip or spine fracture or are taking osteoporosis medications. Participants receive education, regular check-ins every 4 months for 2 years, and support to take their medications correctly. The goa…

This study tests whether adding a precise internal radiation treatment (brachytherapy) after standard external radiation, chemotherapy, and the immunotherapy drug nivolumab can help prevent esophageal cancer from returning. About 60 adults with advanced esophageal squamous cell c…

This study tests whether cilostazol, a drug already used for stroke prevention, can help the brain clear blood clots faster after a bleeding stroke (intracerebral hemorrhage). About 100 adults with small to medium bleeds will receive either cilostazol plus standard care or standa…

This study tests whether choosing antibiotics based on lab tests (personalized) works better than standard antibiotic combinations for people whose H. pylori infection did not clear with first treatment. About 450 adults who failed prior therapy will be randomly assigned to one o…

This study tests whether taking activated bamboo charcoal and probiotics can reduce inflammation and slow the progression of chronic kidney disease in people with diabetes. About 300 participants with different stages of kidney disease will be randomly assigned to receive the sup…

This study tests whether the antibiotic rifabutin can improve treatment for people with lung infections caused by Mycobacterium abscessus that are resistant to the common antibiotic clarithromycin. About 60 adults with active lung disease will receive rifabutin as part of their t…

This study tests a mobile health program that helps women with gestational diabetes adopt healthier habits after pregnancy. The goal is to reduce their future risk of heart disease and diabetes. Researchers will track blood sugar, cholesterol, and baby outcomes in 120 participant…

This study tests whether taking glutamine by mouth can help people with stomach cancer recover muscle mass and nutrition after having their stomach removed. About 120 adults who had stomach cancer surgery will take glutamine supplements, and researchers will measure changes in mu…

This study tests a new, noninvasive eye-tracking system that uses artificial intelligence to check vision in young children, including those with special needs who cannot take standard eye tests. Researchers will enroll 1,300 participants, including typically developing preschool…

This study is testing a new blood test called Nu.Q to see if it can accurately tell whether a lung nodule (a spot found on a CT scan) is cancer or not. Researchers will collect blood from 500 adults who have a lung nodule and need a biopsy or surgery. The goal is to see if the bl…

This study tests whether using an AI tool (VeriSee) to screen for diabetic retinopathy and age-related macular degeneration in regular doctor visits can catch these eye diseases earlier than standard exams. About 4,300 adults with diabetes or aged 50+ will be randomly assigned to…

This study tests a new ultrasound technique called shear wave elastography to help doctors quickly tell whether a patient's kidney problem is new (acute) or long-term (chronic). The goal is to make diagnosis faster and safer in the emergency room, avoiding the need for contrast d…

This study is testing a new balance training system for older adults that uses wearable sensors and artificial intelligence to create personalized exercise programs. The goal is to improve stability, walking, and overall function to help prevent falls. Researchers will enroll 120…

This study aims to prevent gastric cancer in Aboriginal people in remote Taiwan by testing and treating a common stomach infection called H. pylori. The study will involve up to 50,000 adults aged 20-60. Researchers will measure how well the treatment works and whether it reduces…

This study looks at whether a technique called cold snare polypectomy can safely and completely remove medium-sized (10-20 mm) colon polyps. About 120 adults will have their polyps removed this way during a routine colonoscopy. Researchers will track how often the polyps are full…

This study is testing a non-invasive ultrasound device (NaviFUS-ctbTUS) to see if it can safely reduce hand tremors in people with Parkinson's disease, essential tremor, or dystonic tremor. Twelve adults aged 18-80 who don't get enough relief from medication will receive the stim…

This study is testing new 3D-printed smart insoles for people with foot pain from flat feet. Thirty participants will get custom insoles made from a 3D scan of their feet. The goal is to see if these insoles can reduce pain, improve walking, and make daily activities easier.

This study tests whether a robotic pet companion can reduce anxiety and improve success rates of breathing trials in ICU patients on ventilators. 24 adults who have already failed one breathing trial will receive the robotic pet intervention. The goal is to ease anxiety and help …

This study tests whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) can reduce depression, negative symptoms, and improve thinking in people with schizophrenia. About 180 adults with schizophrenia or schizoaffective disor…

This study tests whether using Systane COMPLETE eye drops regularly before cataract surgery can improve the eye surface in people with dry eye. About 150 adults aged 20-85 will use the drops and be monitored with questionnaires and eye exams. The goal is to see if better eye mois…

This study tests whether a training program that combines sensory (touch) and motor (movement) exercises can improve arm and hand function in people who have had a stroke at least six months ago. Researchers will compare this combined training to either sensory training alone or …

This study compares two ways of using a robot to help people who had a stroke more than 3 months ago regain arm and hand function. About 72 adults aged 20-75 will receive 18 therapy sessions over 6 weeks. The goal is to see which robotic training sequence works better for improvi…

This study tests a new way to do a chin-tuck exercise that may help people with swallowing problems (dysphagia). The exercise aims to strengthen throat muscles and improve the movement of the voice box during swallowing. Researchers will study 60 healthy adults and stroke patient…

This study tests a gentle, non-invasive brain stimulation called rtACS in 188 adults with glaucoma. The goal is to see if it can wake up damaged cells in the eye and improve vision, measured by visual field tests. It's an early-stage trial focused on symptom relief, not a cure.

This study tests whether doing mirror therapy before augmented reality training helps stroke survivors improve arm movement and balance. About 75 adults who had a stroke 3 months to 3 years ago will take part. The goal is to see if this combination works better than standard reha…

This study tests a sleep improvement program for children with epilepsy, who often have worse sleep problems than other kids. The program combines clinic visits with technology support to help children sleep better and improve health for both the child and their parents. About 15…

This study tests a new, gentle treatment called cold atmospheric plasma (CAP) for wounds where tubes enter the body in patients on life support. These wounds often heal slowly and get infected. The study will compare standard care alone to standard care plus CAP in 65 adults. The…

This study tests whether using four balloon inflation points works better than two during a procedure to open blocked tear ducts. About 50 adults with a common type of tear duct blockage will take part. The main goal is to see which method reduces tearing symptoms more effectivel…

This study tests if applying a topical gel (indomethacin) to the hands before starting sorafenib can prevent or reduce hand-foot syndrome, a common and painful side effect. About 39 adults with advanced liver cancer will use the gel twice daily for up to 12 weeks. The goal is to …

This study tests a temporary, minimally invasive spinal cord stimulation device to help people with advanced Parkinson's disease who experience freezing of gait—a sudden inability to move their feet. The goal is to improve walking stability and reduce fall risk. Five participants…

This study tests whether a high flow nasal cannula (a device that delivers oxygen through the nose) works better than a face mask for people with chest injuries who have low oxygen levels. About 100 participants will be randomly assigned to one of the two devices. The goal is to …

This study tests a 12-week smartphone-assisted cardiac rehabilitation program for adults with stable heart failure. Participants use a phone app guided by a case manager to exercise safely at home. The goal is to see if this approach improves exercise capacity and quality of life…

This study looks at whether a short, two-week program of aerobic exercise combined with a parent-led sleep education program can improve sleep in children with autism spectrum disorder (ASD). About 120 children aged 3-11 with ASD and sleep problems will take part. The goal is to …

This study looks at whether giving an anxiety-reducing pill (Xanax) before cataract surgery helps patients feel less pain and more satisfied with their anesthesia. About 400 adults having cataract surgery will be randomly given either Xanax or a placebo. Researchers will measure …

This study tests a home-based arm exercise program called GRASP for stroke survivors. The program is designed to improve arm movement and prevent disuse of the affected arm. Researchers will enroll 52 adults who have had a stroke and have some arm movement. Participants will do t…

This study tests whether a gentle, non-invasive ultrasound beam aimed at the brain can help people who recently had a stroke regain arm movement. Fifty adults with stroke within the past three months and limited arm strength will receive the treatment. Researchers will check for …

This study tests a new robot that helps people who had a stroke 6 months to 3 years ago improve their walking. The robot encourages patients to move their legs actively rather than just moving them passively. 60 participants will receive 15 training sessions over 5 weeks, and res…

This study tests whether a non-invasive brain stimulation technique called rTMS can reduce physical distress and health anxiety in people with somatic symptom disorder. Thirty adults aged 20-70 will receive both real and sham (fake) stimulation in a random order, without knowing …

This study looks at whether using Systane COMPLETE eye drops before and after cataract surgery helps people with dry eyes. Researchers will measure changes in eye shape and vision, as well as dry eye symptoms and tear film stability. About 140 adults who already have dry eye and …

This study is developing and testing a friendly AI robot called E-MOTE to provide emotional support to women who have just had surgery for gynecologic cancer. The robot will assess their distress and offer personalized psychological help. Researchers will measure how well the rob…

This study tests whether using a mechanical dilator instead of an electrocautery dilator reduces bleeding when opening blocked bile ducts during an endoscopic ultrasound procedure. About 64 adults who cannot have standard ERCP will be randomly assigned to one of the two methods. …

This study tests a new therapy that combines cognitive-behavioral therapy (CBT) with biofeedback to help people with somatic symptom disorder—a condition where emotional distress shows up as real physical symptoms. Sixty adults diagnosed by a psychiatrist will either receive the …

This study tests whether an AI-powered physiotherapy app can help oral cancer patients regain jaw movement, shoulder function, and overall physical ability after surgery, chemo, or radiation. One hundred adults aged 20-65 will be split into two groups: one using the AI app for 12…

This study looks at whether taking an oral anti-anxiety medication (Alprazolam) before cataract surgery can reduce pain, anxiety, and improve overall satisfaction. It involves 250 adults who are already scheduled for their second-eye cataract surgery. The goal is to find a safe, …

This study tests whether completely avoiding a nasogastric tube (a tube through the nose into the stomach) after pancreatic surgery is as safe and effective as removing it soon after surgery. The goal is to reduce patient discomfort and complications. About 240 adults aged 20–75 …

This study tests a nursing-led program called mHELP@ICU to reduce delirium (sudden confusion) in critically ill patients on breathing machines. About 266 adults will be randomly assigned to receive either the program or usual care. The program includes mental activities, physical…

This study follows oral cancer patients who completed a previous rehabilitation trial. It compares AI-based physiotherapy to standard physiotherapy to see which better improves jaw movement, shoulder function, overall physical health, quality of life, and return to work. Research…

This study tests whether oxybutynin, a medication used for overactive bladder, can help men recover bladder control sooner after robotic prostate cancer surgery. About 135 men will receive either the drug or a placebo daily for up to 3 months. Researchers will track how many achi…

This study creates a training program using simulation and artificial intelligence to teach doctors how to perform heart ultrasound (TEE) during cardiac arrest. About 60 junior emergency physicians will take the course and be tested on their skills. The goal is to see if the AI c…

This study tests whether 12 weeks of small-group reading and writing workshops can improve cognitive health in healthy adults aged 65 and older. Participants will be randomly assigned to an active language-prediction group, a passive reading group, or a board-game group. Research…

This study looks at why some ICU patients bleed longer after a tube is removed from their leg artery following heart procedures. Researchers will track 157 adults to find factors that affect bleeding and the required 6-hour flat bed rest. The goal is to create a tool that predict…

This study tests a program called I-CARE that combines remote support through a smartphone app with in-person clinic visits for people who have been in the ICU. The goal is to see if this program helps reduce unplanned hospital readmissions and emergency room visits, and improves…

This study will follow 5,000 adults in Taiwan who have a chronic total occlusion (CTO) — a complete, long-term blockage in a heart artery. Researchers want to see which patient and procedure factors lead to successful reopening of the artery and better heart outcomes. The goal is…

This study looks at whether a simple ultrasound of the voice box can help predict choking or pneumonia risk in people who recently had a stroke. Researchers will check vocal cord movement with ultrasound and then follow 200 patients for one year to see who develops choking or lun…

This study will develop an AI system to measure how well people can move their jaw, neck, and shoulders. Researchers will compare the AI's measurements to standard methods in 40 healthy adults and oral cancer patients who have trouble moving these areas after treatment. The goal …

This study reviews medical records of 500 adults who had pancreas surgery to find out why some develop delayed gastric emptying (slow stomach emptying). The goal is to identify risk factors like surgery type or feeding tube use, so doctors can better manage this complication and …

This study is looking for substances in urine that could help doctors predict how well prostate cancer treatments will work. Researchers will collect urine samples from 360 men with prostate cancer who are receiving standard treatments like surgery, radiation, chemotherapy, or ho…

This study checks if an AI-based system can accurately measure jaw and neck-shoulder movement in 20 healthy adults, compared to traditional manual methods. The goal is to see if the AI can provide more consistent and objective measurements for oral cancer patients. If successful,…

This study looks at how care in the emergency department (ED) affects short-term survival for adults who had a cardiac arrest outside the hospital. Researchers will analyze data from 6000 patients to see if the timing of treatments like EKGs and medications makes a difference. Th…

This observational study enrolls 30 adults with recurrent or metastatic head and neck squamous cell carcinoma. Researchers will collect blood samples to measure circulating tumor cells and immune cell activity, aiming to link these markers with how long patients live without the …

This study looks at whether a training program that mixes mental tasks with physical exercises can improve thinking and movement in people who have had a stroke or have Moyamoya disease. Researchers will measure brain activity during these tasks using a special headband. The goal…

This study aims to better understand aggressive prostate cancer by analyzing urine samples from 2,000 men. Researchers hope to find new markers that can help detect and prevent serious prostate cancer while reducing unnecessary treatments for harmless forms. Participants include …

This study tests whether a new app with animations and games helps people prepare for a colonoscopy better than the usual paper instructions. About 252 adults will be randomly assigned to one of two education methods. The goal is to see which approach leads to cleaner bowels, hig…

This study looks at whether a type of brain stimulation called rTMS, combined with letting people choose when to get feedback during practice, can improve how well they learn a motor task and how motivated they feel. It involves 72 healthy young adults who will practice tracking …

This study is collecting data from 3500 people who had pancreatic surgery to understand how the operation affects their blood sugar control, digestion, and overall quality of life. Researchers will compare different surgical methods and how much pancreas remains after surgery. Th…

This study explores whether artificial intelligence (AI) can correctly interpret ultrasound images of the heart (pericardial effusion) and kidneys (hydronephrosis). Researchers will develop and test AI models using 300 patients' scans. The goal is to see if AI can match or improv…

This study aims to create and test a simple scale that caregivers can use to spot common eye problems in adults with intellectual disability. Currently, no such tool exists, leading to delayed diagnosis. Researchers will work with 1,400 caregivers and adults with intellectual dis…

This study is observing 500 adults with type 2 diabetes to understand how their mental well-being, depression, and quality of life are connected. Participants will fill out questionnaires about their feelings and daily life. The goal is to find patterns that can help doctors offe…

This study looks at two ways to train emergency room teams for adult cardiac arrest: training right in the busy ER (in-situ) versus training in a separate simulation lab (off-site). About 100 healthcare workers from two hospital campuses will take part. The goal is to see which t…

This study looks at how a specific gene, ALDH2, which helps break down alcohol, might affect how long people with esophageal cancer live. Researchers will follow 700 patients for up to 150 months to see if certain gene variations are linked to better or worse survival. The goal i…

This study will follow 2,000 adults with metabolic syndrome or prediabetes for many years. Researchers will track health changes, risk factors, and complications to better understand how these conditions progress. The goal is to find key factors that affect long-term health outco…

This study looks at how stiff the jaw muscles are in people who have had treatment for oral cancer, and whether that stiffness is linked to how wide they can open their mouth. Researchers will use a special ultrasound to measure muscle hardness and then see if exercise training c…

This study is testing a modified Pap test that adds a painless step at the end to reduce how much pain women remember. The goal is to see if this small change encourages more women to come back for regular cervical cancer screening over the next three years. About 248 women aged …

This study is testing a new job training program that uses virtual reality to help people with schizophrenia improve their job interview skills. About 40 adults aged 20 to 55 who are stable and motivated to work will take part. The goal is to see if the program can boost their ab…

This study follows 600 adults who receive a stem cell transplant to see how many develop a serious lung condition called bronchiolitis obliterans syndrome. Researchers will track symptoms and lung function over time to better understand this complication. The goal is to gather in…

This study is observing 2,000 adults with type 2 diabetes to track changes in their diet, body composition, and grip strength over time. No new treatments or medications are being tested. The goal is to better understand how the disease affects nutrition and physical function.

This study reviews the medical records of 5,000 people who had robotic-assisted urological surgery. The goal is to understand how well the surgery works for cancer control and recovery of normal function. Participants must be 18 or older. No new treatments are given; this is an o…

This study looks at how people with autism process senses like touch, sound, and sight, and how this relates to social difficulties. Researchers will use brain scans and questionnaires to understand these patterns. The goal is to better understand autism, not to test a treatment.…

This study looks at how gestational diabetes and depression affect each other during pregnancy and after childbirth. Researchers will follow 600 women, some of whom will receive health education to see if it helps improve mood and health outcomes. The goal is to better understand…

This study looks at whether letting people with Parkinson's disease choose when they get feedback helps them learn a finger-tapping task. 72 participants will either have control over their feedback or receive it on a fixed schedule. Researchers will compare how well each group r…

This study enrolls 500 people with brain small vessel disease (CSVD) to see how genetics influence their condition. Participants get genetic testing for five key genes and are followed for at least two years. The goal is to track strokes and dementia, not to test a new treatment.

This study tests a new way to predict how well your lungs will work after lung cancer surgery. Doctors use a 3D CT scan to create a virtual model of your lungs and simulate the surgery beforehand. The goal is to improve safety and help plan recovery. About 60 adults with non-smal…

This study looks at rules used by emergency workers to decide when to stop trying to restart a person's heart after a cardiac arrest outside a hospital. These rules were made in Western countries, and researchers want to see if they work well for people in Asia. They will study 1…

This study uses ultrasound to measure how soft tissues like ligaments, tendons, and muscles stretch and move in different groups of people. Researchers will look at baseball pitchers, people with ankle tendon problems, and patients recovering from ACL knee surgery. The goal is to…

This study follows 500 first-time mothers to understand how depression during pregnancy and after childbirth relates to how they feed their infants. Participants complete questionnaires four times from late pregnancy until six months after birth. The goal is to uncover patterns t…

This study looks at how autism affects motor functions like muscle strength, balance, and coordination in adults aged 18 to 45. Researchers will also test whether a 6-week virtual reality training program can help improve these skills. The goal is to better understand the link be…

This study looks at how well people can chew after getting a single dental implant to replace a lost second molar. Researchers will give participants a piece of chewing gum to measure their chewing efficiency. The goal is to understand how implant-supported fixed dentures improve…