National Taiwan University Hospital

This study looks at whether the PCV13 pneumonia vaccine is safe and effective for people with multiple myeloma, a blood cancer that raises infection risk. About 100 participants will get either one or two doses of the vaccine. Researchers will check how well the immune system res…

This study tests whether a Fracture Liaison Service (FLS) — a team that provides education, medication management, and follow-up calls — can improve outcomes for people aged 50+ who have had a hip or spine fracture. 400 participants will be randomly assigned to either FLS or usua…

This study tests a new technique called irreversible electroporation (IRE) for people with liver cancer whose tumors are near major blood vessels and cannot be surgically removed. IRE uses high-voltage electrical pulses to destroy cancer cells without harming nearby blood vessels…

This study looks at 300 adults who had a heart procedure called ablation for atrial fibrillation. It compares two methods of giving the blood thinner heparin: a steady drip versus occasional shots. The goal is to see which method keeps blood clotting time in the ideal range (250-…

This study looks at whether switching to a newer antiviral drug (tenofovir alafenamide) can help people with chronic hepatitis B who experience a flare-up after stopping their previous medication. About 260 adults in Taiwan who had been on standard antivirals for at least a year …

This early study tests if MRI-guided focused ultrasound can safely reduce symptoms in adults with severe obsessive-compulsive disorder (OCD) that hasn't improved with standard treatments. Ten participants will receive the ultrasound procedure and complete brain scans and symptom …

This study tests whether a natural vaginal gel (CH2) can help women with mild cervical changes (CIN1) and high-risk HPV clear the infection faster than a placebo. About 50 women will use the gel or a placebo for several months, with regular check-ups to see if their cervical cell…

This study looks at whether a special vacuum dressing (called incisional negative pressure wound therapy) can reduce wound problems after taking a skin and muscle flap from the thigh for head and neck reconstruction. About 138 adults who need this surgery will be randomly assigne…

This study tests whether a patch made from a donor's aorta (the body's largest blood vessel) can safely repair damaged or narrowed windpipes in infants and children. The approach is for kids who cannot have standard surgery. The main goal is to see if children survive 90 days aft…

This study tests whether a surgery called lymphovenous bypass can help people with diabetic peripheral neuropathy—a common complication causing pain, numbness, and foot ulcers. About 60 adults with diabetes will receive the surgery, and researchers will measure nerve function, pa…

This early-stage trial tests a treatment for corneal endothelial dysfunction, a condition that causes the cornea to swell and blur vision. Doctors take healthy cells from donated corneas, grow them in a lab, and inject them into the patient's eye. The goal is to see if these cell…

This study tests two methods to prevent low blood pressure during surgery: a new AI tool called the Hypotension Prediction Index (HPI) and simply raising the standard monitor alarm to 73 mmHg. About 100 adults having long surgeries will take part. The goal is to see if the expens…

This study looks at whether a nurse-led team can help adults with two or more chronic diseases (like heart failure, diabetes, or kidney disease) get the right medications during a hospital stay. About 178 participants will either receive this extra team support or usual care. Res…

This study looks at whether heart failure patients can get the same benefits from doing spot-jogging at home as they would from going to a clinic for rehab. About 40 adults with heart failure will be assigned to either a home program with adjustable jogging intensity or a standar…

This study looks at whether proteins found in urine can help doctors tell if a thyroid growth is cancerous before surgery. Currently, the only way to diagnose follicular thyroid cancer is to remove the nodule and examine it under a microscope. Researchers are testing urine sample…

This study tests two non-invasive methods—high-resolution oral imaging and a gentle cell-collection technique—to screen for oral cancer. Researchers want to see if these methods can find suspicious spots as well as or better than standard visual exams and biopsies. The study incl…

This study tests whether a new DNA test (mNGS) can help doctors identify the bacteria or virus causing pneumonia faster than standard methods. About 114 ICU patients on breathing machines will be randomly assigned to get either the new test or usual care. The goal is to see if fa…

This study tests whether personalized screening—using stool tests, blood tests, and risk scores—can better prevent stomach and colon cancer in adults aged 50-75. Researchers will enroll 40,000 healthy participants and track them over time. The goal is to find the most effective w…

This study explores whether a special visual training program can help children aged 6 to 10 with mild nearsightedness see better without glasses. Thirty children will be randomly assigned to either a training group that uses a digital vision system for about 3 months, or a contr…

This study looks at two endoscopic procedures that help people with advanced cancer who have a blocked stomach or upper intestine, making it hard to eat or drink. About 200 adults with this condition will receive either a newer ultrasound-guided bypass or a standard metal stent. …

This study looks at whether a high-protein nutritional drink can help cancer patients aged 40 and older who are losing muscle strength (sarcopenia) during chemotherapy. Participants will take the drink three times daily for 8 weeks and do simple home exercises. Researchers will m…

This study tests whether High-Intensity Focused Ultrasound (HIFU) can safely relieve symptoms like pain from abdominal tumors that cannot be removed by surgery. About 38 adults with benign or malignant tumors will receive a single HIFU session, which uses focused ultrasound waves…

This study looks at whether spending time in sunlight can improve sleep problems in people with Alzheimer's disease. Sixty participants will answer sleep questionnaires, receive sunlight therapy, and have their sleep recorded for two weeks. The goal is to see if this simple, natu…

This study looks at two ways to help older adults who are losing mobility: reablement (personalized daily tasks) and standard exercise. About 80 people aged 65+ from day care centers will take part. The goal is to see which approach better improves movement, reduces fear of falli…

This study looks at whether a special recovery program (ERAS) helps children heal faster after lung surgery. About 100 children will take part. The program includes steps to reduce pain and speed up recovery, and the study will measure how long they stay in the hospital and if th…

This study tests two non-invasive brain stimulation methods to reduce depression symptoms in adults who haven't gotten better with antidepressants. Participants receive daily sessions for four weeks, targeting either a standard side-brain area or a deeper middle-brain region. Res…

This study tests whether a ChatGPT-based job coach can help 30 adults with autism spectrum disorder (ASD) improve their job interview performance and workplace social skills. Participants practice with ChatGPT for one week, completing questionnaires and role-play interviews befor…

This study looks at whether adding a single biofeedback session to Kegel exercises can improve bowel function, reduce emotional distress, and boost quality of life in people who had rectal cancer surgery. About 66 adults who have bowel control issues after surgery will be split i…

This study tests two non-invasive devices that stimulate the vagus nerve (one on the neck, one on the ear) to see which better reduces physical discomfort and health-related anxiety in people with Somatic Symptom Disorder. About 60 adults will try both devices in random order, ea…

This study tests whether virtual reality (VR) can help caregivers of children with pneumonia learn chest percussion—a technique to loosen mucus in the lungs. Researchers will compare VR training to standard teaching methods to see if it improves skill accuracy and reduces caregiv…

This study looks at whether a heart ultrasound (called TTE) can help prevent another stroke in people who have already had one. About 2000 stroke patients will be tracked to see if those who get the ultrasound have fewer repeat strokes. The goal is to find out if this common test…

This study looks at how the brains of people with autism, depression, or both differ from those without these conditions. Researchers will use brain scans and electrical recordings to measure brain activity and inflammation. The goal is to better understand these conditions, not …

This study looks at how medical students learn from virtual patients (computer programs) compared to real actors playing patients. About 60 students from National Taiwan University will try both methods and give feedback through surveys. The goal is to see if virtual patients can…

This study aimed to confirm whether certain blood markers (like NT-proBNP and IL-6) are linked to the severity of atrial fibrillation, a common heart rhythm problem. Researchers planned to analyze samples from 266 patients before and after treatment to see if these markers could …

This study looks at whether a neck ultrasound can be as good as a speech therapist's exam for deciding when to remove a feeding tube. About 150 adults who need a feeding tube after an illness will get both tests. Half will follow the ultrasound results and half will follow the th…

This study follows 200 adults in Taiwan who have bronchiectasis, a lung condition that causes widening of the airways and leads to repeated infections. Researchers will track participants' health over time, looking at other medical conditions they may have, how severe their disea…

This study looks at the vision care needs of children and adolescents with special needs, who are much more likely to have vision problems than other kids. Researchers will interview parents, teachers, and caregivers to find out what barriers these children face in getting eye ca…

This study creates a training program to teach nurse practitioners in Taiwan how to use point-of-care ultrasound (PoCUS). About 150 nurse practitioners from different hospitals will take part. Their skills will be tested right after training and again 3 months later using written…

This study is a nationwide registry in Taiwan that will follow 300 people who have or will receive a leadless pacemaker. The goal is to track how well the device works and any complications that may occur during or after the procedure. The study does not test a new treatment but …

This study follows 500 adults with obesity who are trying to lose weight. Researchers collect data on their health, habits, and blood tests to find out what helps or hinders weight loss. The goal is to create personalized weight loss plans based on each person's unique profile.

This study looks at 50 people with partially blocked heart arteries to see if a new measurement method (NTG-Pd/Pa) works better than the standard saline method for diagnosing blockages. Participants will have both tests along with the usual FFR test. The goal is to find which met…

This study looks at how hospital-integrated care services relate to the stress and burden felt by family caregivers. Researchers will survey 200 primary caregivers of hospitalized patients at a medical center in northern Taiwan. The goal is to find ways to better support caregive…

This study looks back at the medical records of 2500 liver cancer patients treated at a major hospital in Taiwan between 2019 and 2024. Researchers want to see how well newer drugs like Pembrolizumab, Atezolizumab, and Lenvatinib work compared to the older drug sorafenib. They wi…

This study looks at whether a special simulation curriculum can help junior doctors become skilled at ultrasound-guided procedures like thoracocentesis and abdominal tapping. About 200 junior doctors will take part. The goal is to improve training without putting real patients at…

This study looks at 350 people who survived a cardiac arrest outside the hospital. Researchers use an artificial intelligence program to analyze brain CT scans and medical records. The goal is to better predict how well patients will recover, helping doctors and families make mor…

This study looks at how infective endocarditis, a serious heart infection, has changed in Taiwan from 2006 to 2022. Researchers will analyze health records from over 2,200 patients to spot trends and improve treatment. The goal is to understand the disease better, not to test a n…

This study tests whether using a special 3D ultrasound during CPR can help find the best place to push on the chest. Researchers will measure how much blood the heart pumps before and after adjusting the compression location. About 50 adults who have a cardiac arrest outside the …

This study looks at whether a shared decision-making tool helps people aged 40-49 with a family history of colorectal cancer choose between colonoscopy and a stool test (FIT). About 2,286 participants will be randomly assigned to use the tool or receive standard care. The goal is…

This study looks at people aged 45-74 who had a positive fecal immunochemical test (FIT) but a normal colonoscopy. Even with a clear colonoscopy, these individuals may still have a higher risk of colorectal cancer later. The trial compares two follow-up options after two years: a…

This study looks at why some people's bodies produce more TMAO—a chemical linked to heart disease—after eating red meat. Researchers are testing whether a specific gene (gbu) in gut bacteria can predict TMAO levels. 230 healthy adults will take carnitine pills and provide blood, …

This study looks at how ups and downs in blood sugar (glycemic variability) impact diabetes self-care, blood sugar control, emotional distress, fatigue, and quality of life in people who have both diabetes and gastrointestinal cancer after surgery. Researchers will also test a ne…

This study looks at whether a structured care plan can help people with a severe type of stroke (brain hemorrhage) start moving earlier and more safely in the hospital. About 198 patients will be included, and the goal is to improve their mobility and reduce long-term disability.…

This study looks at how end-stage kidney disease affects recovery after pancreatic surgery. Researchers will review medical records from 100 patients to see how kidney failure severity and dialysis use impact complications, hospital stay, and costs. The goal is to provide better …

This study looks at two different ways to perform a heart procedure called ablation for a condition called paroxysmal supraventricular tachycardia (PSVT), which causes a fast heart rate. The goal is to see which method works best without using any X-ray radiation. About 70 adults…

This study explores whether substances found in urine can help doctors track thyroid cancer after treatment. Researchers are measuring specific proteins in the urine of 103 patients who had their thyroid removed. The goal is to find a simple, non-invasive way to monitor the disea…

This study looked at CT scans from 2000 adults who had scans for other reasons, not because of appendix problems. The goal was to map where the appendix is usually located in the body. Knowing this can help doctors better diagnose appendix-related issues in the future.