National Taiwan University Hospital

This study tests whether giving two hormone injections (hCG and GnRH agonist) before transferring a frozen embryo can improve the chance of pregnancy. About 170 women aged 24-45 undergoing a modified natural cycle IVF will be randomly assigned to receive either the dual trigger o…

This early-stage trial tests whether empagliflozin, a diabetes drug, can improve abnormal heart electrical patterns in people with Brugada syndrome. Ten adults will take the medicine daily for three months, with monthly checkups to monitor heart changes and side effects. The goal…

This study compares three radiation approaches for people with 6 or more brain tumors that have spread from other cancers. The goal is to find which treatment best protects memory and thinking skills six months later. Participants will receive either focused radiation to each tum…

This study will follow 30 adults with paroxysmal atrial fibrillation (a type of irregular heartbeat) who have or will receive an Amvia pacemaker. The pacemaker can detect abnormal heart rhythms and send data to doctors remotely. Researchers want to see how well it detects these e…

This study compares two bone-strengthening drugs (ibandronate and zoledronic acid) given after stopping denosumab in postmenopausal women with osteoporosis. The goal is to see which drug better maintains bone density and prevents bone loss. The trial involves 52 women aged 50-85 …

This study tests a smart program for people with both knee osteoarthritis and obesity. The program uses AI-guided community exercise and continuous glucose monitoring to help control blood sugar, reduce knee pain, and improve daily function. Researchers will track 312 adults over…

This study tests whether a telemedicine program using a smartphone app and a smartwatch can help manage decompensated cirrhosis, a serious liver condition. About 120 adults with advanced liver disease will use the digital platform to share health data and receive remote check-ins…

This study looks at whether tirzepatide, a drug used for weight loss, can help overweight or obese people with a type of irregular heartbeat called atrial fibrillation (AFib). About 200 adults will receive either tirzepatide injections plus standard care, or standard care alone, …

This early-stage study tests a new approach for people with pancreatic cancer that has spread to the liver and hasn't responded to standard chemotherapy. The treatment combines standard chemotherapy drugs with a special ultrasound technique (sonoporation) that uses sound waves to…

This study is testing a new, custom-made 3D-printed spine implant designed to replace bone removed during spinal tumor surgery. The implant is flexible to encourage better bone fusion and reduce sinking. About 18 adults aged 20-79 with spinal tumors will be followed to check for …

This study tests a new approach for people with HER2-positive early breast cancer. After initial chemotherapy, if scans or DNA tests show remaining cancer, participants get a different drug combination (PLD, cyclophosphamide, trastuzumab, and pertuzumab) to try to eliminate all c…

This observational study will enroll 300 people with suspected lung lesions to see if 3D ultrasound can accurately measure the size and shape of these growths. Researchers will compare the ultrasound results to standard CT scans. The goal is to develop a simpler, radiation-free w…

This study tests a computer program that uses artificial intelligence to quickly check chest X-rays for misplaced breathing or feeding tubes and lung collapse. About 10,900 patients in emergency and intensive care units will take part. The goal is to see if the AI helps doctors f…

This study is testing a new AI-powered electronic stethoscope to see if it can detect breathing problems earlier than current monitors during certain types of anesthesia. Researchers will monitor 60 adults having elective breast surgery where they breathe on their own with a spec…

This study tests a special air mattress that automatically turns ICU patients to prevent bedsores. It compares the new mattress to standard foam mattresses with manual turning by nurses. The goal is to see if the smart mattress reduces nursing workload, saves time, and is cost-ef…

This study compares two ways to prevent colon cancer in people at very high risk. One group gets a colonoscopy every three years as usual. The other group does a simple stool test every year, and only gets a colonoscopy if the test is positive. The goal is to catch and remove dan…

This study tests a nurse-led sleep program combined with a health chatbot for adults who have trouble sleeping. About 80 participants will either get the chatbot-assisted program or track their sleep on their own. The goal is to see if the program improves sleep, anxiety, depress…

This study tests whether high-intensity pulsed electromagnetic fields (HI-PEMF) can help reduce pain and improve daily function after total hip replacement. About 40 adults who had a hip replacement due to osteoarthritis will receive either standard physical therapy or standard t…

This study tests a LINE chatbot that provides visual, interactive tips to help lung cancer patients manage side effects from targeted therapy. About 178 people with advanced lung cancer will either get usual care or also access the chatbot. The goal is to see if the chatbot impro…

This study tests whether a personalized brain stimulation technique, called IAF-based rTMS, can help people recover movement after a first ischemic stroke. Thirty-four adults will receive either active or sham (fake) stimulation over four weeks. The goal is to see if the tailored…

This study tests a non-invasive treatment called histotripsy that uses focused ultrasound to break apart solid tumors in the abdomen without needles or surgery. It is for 30 adults with tumors that cannot be removed and are causing pain or other symptoms. The goal is to see if th…

This study tests whether a numbing medicine called lidocaine can reduce coughing and diaphragm twitching during a heart procedure called pulsed field ablation for atrial fibrillation. About 60 adults with AFib will receive lidocaine or a placebo during the procedure. The goal is …

This study tests if extracorporeal shockwave therapy (ESWT) can reduce pain and improve walking in people with both peripheral neuropathy and plantar fasciitis. About 114 adults with nerve damage and chronic heel pain will receive ESWT. The goal is to see if this non-invasive tre…

This study tests whether a home exercise program delivered through a smartphone app can improve hand strength, muscle endurance, and emotional well-being in people having surgery to remove lung nodules. Sixty adults will follow guided aerobic, resistance, and breathing exercises …

This study looks at 10 oral cancer patients who had neck surgery and now have shoulder blade movement problems. Researchers will use ultrasound to measure changes in a key shoulder muscle and see how it relates to arm movement. The goal is to see if ultrasound can be a useful too…

This study is testing a new wearable device that tracks muscle activity during swallowing. Researchers will compare the device's readings with standard hospital tests. They plan to enroll 20 healthy adults and 20 people with swallowing difficulties (dysphagia). The goal is to see…

This study will follow 100 people who have had their stomach removed (gastrectomy) to see how much muscle they lose afterward. Researchers will measure muscle thickness in the arms and legs over time. The goal is to better understand muscle loss and nutrition after surgery, not t…

This study compares two methods—mixed reality goggles and ultrasound—to help surgeons mark broken ribs before surgery. About 30 adults with three or more rib fractures will take part. The goal is to see which method is more accurate and faster for planning the operation.

This study aims to measure how much zirconia, a hard ceramic used in dental crowns, is removed with each grinding stroke during adjustments. Researchers will have 120 participants—dental students, interns, and experienced clinicians—grind standardized zirconia blocks and then sca…

This study tests whether an artificial intelligence (AI) system can help doctors find hidden atrial fibrillation (an irregular heartbeat) in people who have had a stroke. About 400 participants will be split into two groups: one gets AI-guided monitoring with wearable devices and…

This study tests whether extended reality (XR) can help doctors more accurately locate small lung nodules during a CT scan before surgery. About 30 adults aged 18 to 80 with small nodules in the outer part of the lung will take part. The goal is to see if XR guidance improves acc…

This study aims to create and test a new training program for using portable ultrasound (PoCUS) in hospital-at-home care. About 100 medical residents will be split into two groups: one learns through peer training with remote supervision and simulation, the other through traditio…

This study looks at whether getting a CT scan sooner after a heart attack outside the hospital helps people survive. Researchers will review records from 5000 adults who had a heart attack, were revived, and then had a CT scan. The goal is to see if earlier scans are linked to be…

This study looks at why some people have higher levels of TMAO—a substance linked to heart disease—after eating red meat. Researchers will test if a specific gene (gbu) in gut bacteria can predict TMAO levels. 65 healthy adults will eat a large amount of beef, and their blood and…

This study will check if working night shifts harms the heart's ability to relax and fill with blood, a condition called diastolic dysfunction. Researchers will compare healthcare workers who work nights with those who don't. About 60 participants will fill out surveys, get a hea…

This study tests a non-invasive tool that predicts when a patient's blood pressure might drop dangerously low during shoulder surgery. It involves 60 older adults (ages 65-90) having shoulder arthroscopy in a beach chair position. The goal is to see if using this tool helps preve…

This study tests whether a special headset (extended reality, or XR) can help surgeons plan the removal of cancerous lymph nodes in the neck of people with lung cancer. Ten patients will have their PET and CT scans combined into a 3D model that the surgeon views through the heads…

This study aims to improve how doctors predict and monitor thyroid cancer by combining tumor genetics with proteins found in urine. Researchers will follow 100 newly diagnosed thyroid cancer patients to see if these markers can detect cancer recurrence earlier than current method…

This study looks at mouth cancer patients who use a special plate called an obturator to help them swallow. Researchers will measure tongue strength and biting force and compare them to what patients eat each day. The goal is to better understand how to improve eating ability and…

This study aims to collect normal swallowing data from 80 healthy Chinese adults aged 18 and older. Researchers will use special tests to measure throat pressure and swallowing function. The goal is to create a reference for doctors to better identify and treat swallowing problem…

This study looks at whether having an orgasm within 36 hours before prostate cancer surgery makes the seminal vesicles smaller and easier for the surgeon to remove. Forty men scheduled for prostate removal will be randomly assigned to either ejaculate or abstain for at least 72 h…

This study will survey about 1,000 nurses and nurse practitioners in Taiwan to learn how they use point-of-care ultrasound (POCUS) in their daily work. The goal is to understand their knowledge, how often they use it, and what helps or hinders its use. Results will help improve t…

This study tests whether a special monitoring tool, called the Hypotension Prediction Index (HPI), can help doctors manage low blood pressure during oral cancer surgery. The tool predicts drops in blood pressure before they happen, allowing early treatment. The study will include…

This study tests a culturally tailored decision aid for Taiwanese women thinking about elective egg freezing. About 120 women will either use the decision aid or receive standard counseling. The goal is to see if the tool improves knowledge, reduces regret and distress, and helps…

This study aims to create a standard method for collecting and analyzing skin oil (sebum) to find biomarkers for skin diseases like acne, eczema, and psoriasis. Researchers will study 200 participants, including healthy people and those with skin conditions, to see how skin oil c…