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No heat needed: cold snare could make polyp removal safer

NCT ID NCT07114380

Symptom relief Sponsor: National Taiwan University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether a technique called cold snare polypectomy can safely remove 10-20 mm colon polyps without using heat. About 120 adults will have their polyps removed this way during a colonoscopy. The goal is to see if it works well and causes fewer complications than traditional methods.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
cold snare polypectomy (device procedure)
What this could lead to
If successful, this technique could offer a safer, simpler way to remove medium-sized polyps during colonoscopy, reducing the need for electrocautery and its risks.
What could go wrong
This is an early feasibility study with only 120 participants, so results may not apply to all patients. The procedure may fail to remove some polyps or cause bleeding.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 120 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2025

Expected to finish

Apr 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 20 years * Undergoing colonoscopy for any clinical indication * Found to have a 10-20 mm pedunculated colorectal polyp suitable for cold snare polypectomy Exclusion Criteria: * Age \< 20 years * Medical contraindications to colonoscopy or polypectomy (e.g., recent myocardial infarction, stroke, severe unstable cardiovascular disease, acute peritonitis, fulminant colitis, perforation, or toxic megacolon) * Inadequate bowel preparation preventing complete colonoscopy or safe polypectomy

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Conditions

The condition(s) this trial relates to.

polyp of colon polyp of large intestine

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

10-20 MM pedunculated colorectal polyp

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    5 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • National Taiwan University Cancer Center

    RECRUITING

    Taipei, Taiwan

  • National Taiwan University Hospital

    RECRUITING

    Taipei, Taiwan

  • National Taiwan University Hospital Hsin-Chu Branch

    RECRUITING

    Hsinchu, Taiwan

  • National Taiwan University Hospital, Bei-Hu Branch

    RECRUITING

    Taipei, Taiwan

  • National Taiwan University Hospital, Jinshan Branch

    RECRUITING

    New Taipei City, 20844, Taiwan

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