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Can a colder snip cut bleeding risks in colon polyp removal?

NCT ID NCT05930041

Disease control Sponsor: Showa Inan General Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time

Summary

This trial asks whether a newer, simpler technique called cold snare polypectomy (CSP) causes less damage to blood vessels under colon polyps than the traditional hot snare method. It involves adults with non-cancerous colon polyps sized 10-19 mm. The study compares the presence of injured arteries and the rate of delayed bleeding between the two procedures, potentially offering a safer option for polyp removal.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Cold snare polypectomy (CSP) procedure
What this could lead to
If CSP proves safer, it could become the preferred method for removing medium-sized colon polyps, reducing post-procedure bleeding and simplifying the procedure.
What could go wrong
This is a single-center trial with a modest sample size, and results may not apply broadly. The procedure might not be as effective at complete removal, potentially increasing recurrence risk.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

124 people

The number who actually took part.

Started

Jan 2023

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * at least one polyp sized 10-19 mm (Paris classification Is or IIa) revealed by endoscopic examination. Exclusion Criteria: 1. American Society of Anesthesiologists status class 3 or above 2. poor bowel preparation (Boston Bowel Preparation Scale \<6 points) 3. endoscopic features indicating submucous infiltration or malignancy 4. oral anticoagulants,or antiplatelet agents, or known blood coagulation disorders, or bleeding tendency 5. a history of colorectal resection 6. emergent colonoscopy (haemodynamic instability and/or continued active gastrointestinal bleeding and/or requiring intensive care patients) 7. inflammatory bowel disease, familial polyposis and colorectal cancer 8. pregnancy or lactation 9. severe cardiopulmonary dysfunction, cirrhosis, chronic kidney disease, other malignant tumours or severe infectious diseases.

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Conditions

The condition(s) this trial relates to.

polyp of colon polyp of large intestine

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Colonic polyp

Contacts and locations

Locations

  • Showa Inan General Hospital

    Komagane, Nagano, 399-4117, Japan

More trials for these conditions

Other studies related to the condition(s) this trial covers.