PROSTATE CANCER

This study tested a combination of two drugs, talazoparib and temozolomide, in 16 men with advanced prostate cancer that had spread and stopped responding to hormone therapy. The goal was to find the safest dose and see if the treatment could shrink tumors. The study was complete…

This study tested two different drug combinations in over 1,300 men with newly diagnosed prostate cancer that had spread. One group received standard hormone therapy plus bicalutamide, the other received hormone therapy plus TAK-700. The main goal was to see which combination hel…

This study tested three different drug combinations in 292 men with advanced prostate cancer that no longer responds to hormone therapy and has spread. The goal was to see if adding nivolumab (an immunotherapy) to either rucaparib, docetaxel, or enzalutamide could shrink tumors o…

This study tested a cancer vaccine called ETBX-011 in 43 people with advanced colorectal, lung, breast, or prostate cancers that make a protein called CEA. The vaccine uses a modified virus to teach the immune system to find and attack CEA-making cancer cells. The main goals were…

This study tested a combination of two drugs, abiraterone acetate and prednisone, in 131 men with advanced prostate cancer that had not yet spread to other parts of the body. The goal was to see if the treatment could lower PSA levels (a marker of cancer activity) and delay the t…

This study tested whether adding short-term hormone therapy to high-dose radiation helps men with intermediate-risk prostate cancer live longer. Over 1,500 men participated, and the results showed that the combination improved survival rates. The treatment aims to control the dis…

This study tested if adding two newer drugs (apalutamide and abiraterone) to standard hormone therapy could better control prostate cancer that came back after surgery. It involved 504 men with rapidly rising PSA levels. The main goal was to see how long it took for PSA to rise a…

This study followed 354 men with prostate cancer who chose to freeze half of their prostate gland (hemi-gland cryoablation) to destroy tumors. Researchers tracked how well the treatment controlled cancer and its impact on urinary function. The goal was to see if using advanced MR…

This pilot study tested a new way to treat low-risk prostate cancer using MRI-guided laser ablation. Seven men with early-stage prostate cancer received the treatment to see if it was safe and could successfully target and destroy tumors. The goal was to control the disease with …

This study tested a new type of radiation therapy for low- and intermediate-risk prostate cancer that delivers a higher dose each day, reducing total treatments from 45-48 to just 5 over 2 weeks. 120 participants received this ultra-hypofractionated, image-guided radiotherapy. Th…

This study tested a single, high-dose radiation treatment for men with low-risk prostate cancer. The goal was to see how well the body tolerates this one-time procedure by tracking side effects in the urinary and digestive systems for 6 months. 35 men participated, and the treatm…

This study tested a type of internal radiation called high-dose brachytherapy in 43 people with cervical, endometrial, esophageal, prostate, or biliary cancer. The goal was to see if the radiation implants could be placed accurately to deliver a high dose directly to the tumor. P…

This study tested a drug called enzalutamide in 1401 men with a type of prostate cancer that has stopped responding to hormone therapy but has not yet spread. The goal was to see if enzalutamide could delay the cancer from spreading to other parts of the body. Participants took e…

This study tested a device called the Vanquish System that uses heat to destroy cancerous tissue in the prostate. It involved 32 men with early-stage prostate cancer who were already scheduled for prostate removal surgery. The goal was to see if the treatment was safe and how wel…

This study looked at whether eating a whole food plant-based diet for six months can help men with prostate cancer who have rising PSA levels. Eleven men attended cooking classes and ate mostly plants. Researchers measured PSA, cholesterol, blood sugar, and inflammation markers t…

This study tested a drug called 177Lu-PSMA-617 in 94 people in Japan with a type of advanced prostate cancer that had stopped responding to hormone therapy. The drug delivers radiation directly to cancer cells. The goal was to see if it could shrink tumors and how safe it was. Th…

This study tested whether adding a drug called TAK-700 to standard hormone therapy and radiation could better control high-risk prostate cancer. About 239 men participated. The goal was to see if the stronger hormone combo delayed cancer recurrence, but patients still need ongoin…

This small pilot study tested whether blocking the blood supply to one side of the prostate (prostatic arterial embolization) can control low-risk prostate cancer in men who are already on active surveillance. Ten men with unilateral, low-volume tumors participated. The main goal…

This study tested whether combining several immunotherapy drugs could help people with advanced prostate cancer that no longer responds to hormone therapy. 59 adults received different combinations of a vaccine and other immune-boosting drugs. The goal was to see if these combina…

This study tested a shorter course of radiation therapy (16 sessions instead of the usual 40+) for men with early-stage prostate cancer. The goal was to see if this approach is safe and effective at controlling the cancer while reducing side effects. 91 men participated, and rese…

This study tested a combination of two drugs, Radium-223 and enzalutamide, in 45 men with advanced prostate cancer that had spread to other parts of the body and was no longer responding to standard hormone therapy. The main goal was to see if the combination was safe and tolerab…

This study tested whether giving anti-testosterone drugs before, during, and after high-dose, targeted radiation can prevent very high-risk prostate cancer from returning. 64 men with aggressive prostate cancer took part. The goal was to see if this combination keeps PSA levels l…

This study checked the long-term safety of the drug degarelix in men with prostate cancer. Participants had already completed an earlier study and continued treatment for up to 5 years. The main goal was to see if any serious side effects occurred over time.

This study tested a focused ultrasound (HIFU) treatment for men with intermediate-risk prostate cancer that has not spread. The goal was to destroy only the cancerous part of the prostate, avoiding common side effects like incontinence and impotence from standard treatments. 174 …

This study tested a new way to treat men with advanced prostate cancer that no longer responds to standard hormone therapy. Fifteen men took high-dose oral testosterone for one week, then no treatment for one week, repeating for three months. If the cancer worsened, they switched…

This early-stage study tested a very focused type of radiation (SBRT) given in just 5 sessions to men whose prostate cancer returned after earlier radiation. The goal was to find the highest safe dose and see what side effects occur. Seventeen men took part, and the study is now …

This study tested whether adding a prostate cancer vaccine (PROSTVAC) and chemotherapy (docetaxel) to standard hormone therapy works better than hormone therapy alone for men whose prostate cancer has spread. 74 men with metastatic castrate-sensitive prostate cancer took part. Th…

This study tested whether injecting a man's own bone marrow stem cells into the penis could help restore natural erections after prostate cancer surgery. 18 men with localized prostate cancer and normal erections before surgery took part. The main goal was to check safety, and th…

This study tested whether adding a radioactive drug called radium-223 to standard targeted radiation (SBRT) helps control prostate cancer that has come back in a few places but is still hormone-sensitive. Twelve men participated and were randomly assigned to get either SBRT alone…

This early-stage study tested a new drug combination for men with a hard-to-treat type of prostate cancer that has spread. The goal was to see if adding relacorilant to the standard drug enzalutamide is safe and how the body handles it. 42 men took part in this phase 1 trial, whi…

This study tested a new drug, BXCL701, taken as a pill, together with the immunotherapy pembrolizumab in men with advanced prostate cancer that has stopped responding to hormone therapy. The goal was to find the best dose and see if the combination could shrink tumors or slow the…

This study tested a new drug called ARN-509 in 127 men with advanced prostate cancer that had stopped responding to standard hormone therapy. The goal was to find a safe dose and see if the drug could lower PSA levels, a marker of cancer activity. The drug was given as a daily pi…

This study tested whether adding a bone-seeking radioactive drug (Radium-223) to targeted radiation (SABR) helps men with prostate cancer that has spread to a few spots (oligometastatic). 64 men participated, and the main goal was to see how long the cancer stayed under control. …

This study tested whether combining two immunotherapy drugs (nivolumab and ipilimumab) works better than standard chemotherapy (cabazitaxel) or one immunotherapy alone in men with advanced prostate cancer that no longer responds to hormone therapy. A total of 351 men participated…

This study looked at men with a type of advanced prostate cancer that no longer responds to hormone therapy and has only a few spots of spread (oligometastatic). It tested whether adding focused radiation to standard treatment could delay the cancer from getting worse. The trial …

This study looked at 588 men with intermediate-risk prostate cancer to see if adding external beam radiation to brachytherapy (placing radioactive seeds directly into the tumor) works better than brachytherapy alone. The goal was to control the cancer and prevent it from coming b…

This trial tested a technique called Kilovoltage Intrafraction Monitoring (KIM) during prostate cancer radiation therapy. The goal was to see if KIM helps doctors target the tumor more accurately, which could lower side effects. 49 men with low- or intermediate-risk prostate canc…

This study tested a new treatment for men whose prostate cancer returned after initial radiation therapy. It combined a local treatment (brachytherapy) with a targeted radioactive drug (177Lu-PSMA) that can also reach cancer cells outside the prostate. The goal was to control the…

This study tested whether implantable spacers can safely reduce radiation damage to nearby organs in men receiving radiotherapy for prostate cancer. 175 men who had already received the spacer were evaluated. The goal was to see if the spacer helped lower the radiation dose to th…

This early study tested whether a laser can safely destroy prostate cancer tissue using MRI and ultrasound guidance. Ten men with early-stage prostate cancer received the treatment in a doctor's office. The main goal was to check for side effects and see if the procedure is feasi…

This study tested a new treatment for men with intermediate-risk prostate cancer that uses a 3D map to guide microwaves and destroy only the main tumor. 76 men across Europe received the therapy, and researchers checked if the cancer was gone after 12 months. The goal was to cont…

This pilot study tested whether a daily supplement of curcumin (from turmeric) and piperine (from black pepper) could slow or stop disease progression in 30 patients with early-stage prostate cancer, MGUS, or low-risk smoldering multiple myeloma. Participants took the supplement …

This early-phase study tested whether giving testosterone skin patches in cycles with the drug enzalutamide is possible and safe for men with castration-resistant prostate cancer. Thirty men on standard hormone therapy participated. The goal was to see if at least half of eligibl…

This study looked at 74 men with prostate cancer that had come back in up to 5 pelvic lymph nodes after initial treatment. They received high-dose radiation to those spots plus hormone therapy. The goal was to see if this approach could delay the cancer from growing again. The ma…

This study looked at how well a combination of two drugs (apalutamide and abiraterone) works in Black and White men with advanced prostate cancer that has spread and is no longer responding to hormone therapy, but who have not yet had chemotherapy. 93 men took the drugs daily, an…

This study tested a precise type of radiation (SBRT) in 86 men with prostate cancer that had started growing despite hormone therapy. The goal was to see if zapping just the growing spots could slow the cancer down and delay the need for chemotherapy. The researchers also looked …

This study tested a new type of radiation therapy (177Lu-PSMA) in 58 men with prostate cancer that had spread to a few spots in the bones or lymph nodes but was still hormone-sensitive. The treatment targets cancer cells specifically, aiming to delay disease progression compared …

This study tested a shorter radiation treatment called proton-based SABR for men with early-stage prostate cancer. Instead of the usual eight weeks, patients received five treatments over two weeks. The goal was to see if this approach keeps side effects low and maintains quality…

This study tested the drug nivolumab in 8 men whose prostate cancer returned after initial treatment and who had specific genetic changes (MMR-deficient or CDK12-altered). The goal was to see if nivolumab could lower PSA levels without using hormone therapy. While the approach of…

This study compared two types of radiation therapy for men with intermediate-risk prostate cancer: standard image-guided external beam radiation (IGRT) alone versus IGRT plus a high-dose-rate brachytherapy boost. The goal was to see which approach is more effective and has fewer …

This study tested a device called Pelvic Clock® to help men recover bladder control and sexual function after robotic prostate cancer surgery. 60 men aged 55-80 took part. The device was compared to standard pelvic floor exercises. The goal was to see if more men could achieve ca…

This study looked at 94 men with advanced prostate cancer that was no longer responding to standard hormone therapy. Researchers tested whether increasing the daily dose of abiraterone from 1000 mg to 2000 mg could stop the cancer from growing. The goal was to see if the higher d…

This study tested whether using MRI to guide prostate biopsies finds more aggressive cancers than the usual method of taking random samples. 275 men with suspected prostate cancer each received both standard and MRI-targeted biopsies. The goal was to see if the MRI approach detec…

This study tested a special dye called IS-002 that makes prostate cancer cells glow under near-infrared light during robotic surgery. The goal was to help surgeons see and remove all cancer while sparing healthy tissue. Fifty-nine men with prostate cancer took part. The study com…

This study tested a new AI tool that combines a simple blood test (cell-free DNA) with MRI scans to improve prostate cancer detection. The goal was to help men with borderline PSA levels avoid unnecessary biopsies. Over 1,600 men participated, and the AI model was designed to pre…

This study looked at whether prostate cancer cells can be found in blood or urine samples without needing a needle biopsy. Researchers used a special filtering technology to capture tumor cells from 127 men with suspected prostate cancer. The goal was to see if this simple test c…

This study tested a new type of PET scan that uses a radioactive tracer called 89Zr-DFO-huJ591 to find prostate cancer that has spread to other parts of the body, especially bones. 77 men with metastatic prostate cancer took part. The goal was to see if this scan is safe and more…

This study tested a new type of PET/CT scan using a radioactive tracer called copper Cu 64 PSMA I&T to see if it can accurately find prostate cancer that has come back after initial treatment. 235 men with rising PSA levels after surgery or radiation took part. The goal was to se…

This study tested a new imaging agent called [18F]CTT1057 for PET scans to find prostate cancer that has come back after initial treatment. About 190 men with rising PSA levels (a sign of possible recurrence) took part. The goal was to see how accurately the scan could locate can…

This study looked at 60 men with suspected prostate cancer to see if a newer imaging method (Ga-68 PSMA PET/CT) is better than the standard MRI for guiding a biopsy. The goal was to find out which method helps doctors detect more significant cancers. Results could lead to more ac…

This study tested whether an artificial intelligence (AI) system could help find prostate cancer on MRI scans as well as expert radiologists. 365 men who needed a prostate biopsy took part. Researchers compared how often AI and radiologists spotted suspicious areas that turned ou…

This early-stage study tested a new radioactive imaging agent, rhPSMA-7.3 (18F), in 24 people—some healthy and some with prostate cancer. The goal was to see if it is safe and can help doctors see prostate cancer on scans. The study focused on safety and how the agent spreads thr…

This study tested whether using MRI to guide prostate biopsies works as well as the standard 12-sample systematic biopsy. 108 men aged 45-75 with elevated PSA levels participated. The MRI-targeted approach used 3 samples from suspicious areas, and it found cancer at similar rates…

This study involved 62 men whose prostate cancer had returned after surgery, shown by a small rise in PSA levels. Researchers compared two types of PET scans to see which one had less urine activity in the bladder, which can hide cancer spots. The goal was to find which scan migh…

This study tested whether an FDA-approved dye called Cytalux can help surgeons find cancer that is not visible to the naked eye during prostate cancer surgery. Nine adult men with aggressive prostate cancer received the dye before surgery, and surgeons used a special camera to lo…

This study tested a new type of PET scan (rhPSMA 7.3) to see if it can safely and accurately find prostate cancer that has come back in men with rising PSA levels after initial treatment. 391 men with suspected recurrence received the scan, and doctors checked if the scan correct…

This study tested new deep-learning MRI sequences to see if they can detect prostate cancer as well as standard scans, but faster. Researchers compared image quality and diagnostic accuracy in 34 men. The goal is to make prostate MRI quicker and more efficient without missing sus…

This study tested a new way to biopsy the prostate using MRI guidance through the perineum (the area between the scrotum and anus) instead of the standard approach through the rectum. The goal was to see if this method causes fewer complications and hospital readmissions, and if …

This study checked if specially trained dogs can detect breast, lung, prostate, or colorectal cancer just by smelling a person's breath. Over 1,300 adults gave breath samples by breathing into a mask. The dogs then sniffed the masks and said whether they thought cancer was presen…

This study tested a new radioactive imaging agent called 68Ga-OncoACP3 in 20 men with prostate cancer. The goal was to see if it is safe and to measure how much radiation the body receives. The agent helps doctors see where the cancer is located using a special scan.

This study tested a simple, rapid PSA test that uses whole blood to see if it works as well as the standard lab test for prostate cancer screening. Researchers compared results from 94 patients with prostate cancer or benign prostate disease. The goal was to see if the quick test…

This study tested a new imaging agent called 68Ga-NTA-476 for PET scans in 10 men with prostate cancer. The goal was to see how the agent spreads in the body and compare it to the current standard scan. Researchers also checked for side effects. This was the first human test of t…

This study tested a new PET imaging agent called [18F]CTT1057 to see how well it can find prostate cancer tumors. 195 high-risk patients who were scheduled for surgery received the scan, and the results were compared to tissue samples taken during surgery. The goal was to see if …

This study tested whether a new, high-resolution ultrasound (micro-ultrasound) can find aggressive prostate cancers as well as MRI does. Over 800 men with suspected prostate cancer were randomly assigned to biopsy guided by micro-ultrasound, MRI, or both. The goal was to see whic…

This study tested whether acupuncture, given before a prostate biopsy, can reduce pain and anxiety during the procedure. 72 men were randomly assigned to receive either real acupuncture or a sham (fake) version, in addition to standard numbing medicine. Researchers measured pain …

This study tested if a TENS device, which sends mild electrical pulses through the skin, can help reduce pain during a prostate biopsy. 84 men were randomly assigned to receive TENS plus local anesthesia, a fake TENS device plus local anesthesia, or local anesthesia alone. Resear…

This study tested a web-based program called True North Peer Navigation for men recently treated for prostate cancer. The program connects men with trained peer navigators who provide practical information and emotional support. Researchers measured whether the program helped men…

This study tested a shorter course of radiation (2 to 4 weeks instead of 6 to 7) for men whose prostate cancer came back after surgery. The goal was to find the shortest schedule that is safe and does not cause severe side effects. Thirty men participated, and the researchers foc…

This small pilot study looked at whether acupuncture can reduce hot flashes and night sweats in men with prostate cancer who are on hormone therapy. Twelve patients took part to see if the treatment was acceptable and effective. The goal was to improve quality of life by easing t…

This small study tested a 3-month program where men with prostate cancer on hormone therapy followed a nightly fasting schedule and received text-based health coaching. The program was found to be feasible and well-liked by participants, with some improvements in weight and quali…

This study tested whether using the UroLift system before radiation therapy is safe for men with both prostate cancer and an enlarged prostate (BPH). Fifteen men participated. The goal was to see if this combination could help manage urinary symptoms without causing serious side …

This study tested a special barbed stitch (Symmcora) for closing the bladder after robot-assisted prostate removal in 70 men with prostate cancer. The goal was to see if it made the stitching step faster without causing more problems like leaks. Results will show if this stitch i…

This study tested a program called ActiveHeal EST (Engage-Sustain-Triumph) to help 30 adults with breast or prostate cancer keep doing daily activities despite challenges. Participants were diagnosed within the last year and could still be in treatment. The program aims to improv…

This study tested whether testosterone replacement therapy (TRT) can safely improve symptoms like low energy and sexual problems in men who had their prostate removed for cancer. 136 men with low-risk prostate cancer and stable PSA levels took part. The goal was to see if TRT cou…

This study tested whether a prehabilitation program—including exercise and education—before robotic prostate removal helps men regain quality of life more quickly after surgery. One hundred men with localized prostate cancer participated. The program aimed to speed up recovery of…

This study tested whether using buffered lidocaine (a less acidic numbing medicine) reduces pain during prostate biopsy. 350 adults scheduled for a prostate biopsy took part. Researchers measured pain from the numbing injection and the biopsy itself, and asked if participants wou…

This study tested a program that teaches men healthy habits before prostate cancer treatment to reduce side effects like incontinence and sexual problems. 140 men scheduled for surgery or radiation took part. The program used daily texts and emails to encourage exercise and conne…

This pilot study tested a program called PROWESS that uses fitness trackers and coaching to help Black and Hispanic men with prostate cancer exercise more while on hormone therapy. The goal was to reduce treatment side effects and improve quality of life. Fourteen men participate…

This study tested whether watching 360° virtual reality movies can help lower fear and anxiety in cancer patients before they start radiation treatment. 292 adults with breast, lung, prostate, head and neck cancer, or a brain tumor took part. Researchers measured their stress lev…

This study looked at whether giving a lower dose of the steroid dexamethasone before the chemotherapy drug docetaxel is safe for people with breast or prostate cancer. The goal was to reduce steroid side effects like high blood sugar, mood changes, and immune suppression while st…

This study looked at whether showing patients a short video before a prostate biopsy could help them feel less pain and anxiety. 223 men were split into three groups: one got only verbal instructions, another got verbal instructions plus static images, and the third got verbal in…

This study tested a gel-like spacer placed between the prostate and rectum to protect the rectum during radiation therapy for prostate cancer. Twenty men who were already scheduled for radiation with a hydrogel spacer took part. The main goal was to see if the spacer reduced the …

This study tested whether a remote exercise training program is practical for medically underserved men receiving hormone therapy (ADT) for prostate cancer. Twenty-seven participants were enrolled to see if they would stick with the program and complete assessments. The goal was …

This study looked at whether androgen deprivation therapy (ADT), a hormone therapy for prostate cancer, affects how well the heart pumps blood. Researchers compared heart function in prostate cancer patients who had ADT, those who did not, and cancer-free individuals. The goal is…

This study tested an online decision aid called 'Talk to Nathan' to see if it helps men aged 55-69 make informed choices about prostate cancer screening. 88 men used the tool, a standard decision aid, or standard education materials. Researchers measured changes in knowledge, dec…

This study looked at whether a care plan led by a geriatrician and a trained nurse could improve survival and quality of life for older adults (70+) with advanced cancer. 792 patients with breast, colorectal, lung, prostate, bladder, ovarian cancer, or lymphoma took part. The app…

This study tested whether combining three types of scans (PET-CT, choline, and MRI) can better map prostate cancer for radiation therapy. Twenty high-risk prostate cancer patients received the triple scan, and researchers compared the tumor outlines to those from standard scans. …

This study looked at how common muscle loss (sarcopenia) is in men aged 70 and older with prostate cancer who are treated with radiation and hormone therapy. The goal was to understand risk factors and how hormone therapy affects muscle mass. 112 men participated, and researchers…

This study looked at how the antibiotic rifampicin changes the way the body processes HRS-5041, an experimental drug for prostate cancer. Sixteen healthy men took HRS-5041 alone and then with rifampicin to compare drug levels. The goal was to gather safety and dosing information,…

This study tested whether combining PET/MRI scans with machine learning can more accurately determine how aggressive solid tumors like prostate cancer are. Researchers scanned 50 adults with prostate, liver, kidney, or brain tumors and compared the AI results to standard tissue a…

This study tested whether a brief educational session in the clinic could encourage more men with prostate cancer to get germline genetic testing. Researchers enrolled 50 men who were recommended for testing based on national guidelines. The main goal was to see how many would ag…

This study looked at two ways to handle a rise in PSA levels after prostate cancer surgery. One group got radiation therapy right away, while the other group was monitored with regular PSA tests and only had a special scan when PSA rose further. The goal was to see if waiting and…

This study tested two different PET scan methods (68Ga-RM2 and 68Ga-PSMA-617) in 14 men with intermediate-risk prostate cancer who were scheduled for prostate removal surgery. The goal was to see which scan better shows the cancer. The study did not provide treatment, only compar…

This study asked 51 men with localized prostate cancer and their healthcare providers how they feel about using artificial intelligence (AI) to help diagnose the disease. Researchers also asked if they would be willing to share their health data to improve AI tools. The goal was …

This early-stage study looked at the safety of a single dose of an angelica herbal supplement (AGN-Cogni.Q) in 12 men aged 40 and older with prostate cancer. Researchers checked heart health and blood tests for any side effects, and measured how the body absorbs the supplement's …

This study reviewed medical records from cancer clinics to see how long men with metastatic prostate cancer that still responds to hormone therapy take two common drugs, apalutamide and enzalutamide. It included about 1,300 men aged 18 and older who started one of these drugs as …

This study analyzed medical records of 507 prostate cancer patients from the Veterans Affairs health system who started taking relugolix. Researchers looked at where patients lived, what other treatments they had, and their overall health. The goal was to describe the types of pa…

This pilot study tested a web-based tool called MAP to help men aged 55+ with low-risk prostate cancer stay on active surveillance. The tool provides information and reminders about needed tests and how their primary care doctor can help. The study enrolled 39 men and measured ho…

This study collected MRI and 3D ultrasound images from 2 men who had their prostate removed due to cancer. The goal was to create a database that researchers can use to develop a computer system that spots tumors without needing a biopsy. This early step focuses on gathering data…

This study looked at 1,247 patients in the United States with a type of advanced prostate cancer called metastatic castration-resistant prostate cancer (mCRPC) who were treated with a drug called Lutetium-177 vipivotide tetraxetan (177Lu-PSMA-617). The goal was to understand the …

This study examined whether PSA blood tests for prostate cancer help men aged 75 to 79 live longer. Researchers analyzed data from over 257,000 Swedish men without prior prostate cancer, comparing those who were screened to those who were not. The goal was to see if screening imp…

This study collected blood and urine samples from 61 men with prostate cancer and healthy volunteers. Researchers analyzed the samples to find genetic differences between cancer cells and normal cells. The goal is to develop a non-invasive way to detect and monitor prostate cance…

This study tested a new automated method to grow cancer cells from patients inside chicken eggs. Researchers used samples from 101 people with metastatic cancers like prostate, breast, and lung cancer. The goal was to see if the automated system could successfully grow tumors at …

This study tested whether a multimedia educational program helps African American men and their doctors make shared decisions about prostate cancer screening. 161 African American men aged 40-69 who had no prior prostate cancer took part. Half received the educational program, an…

This completed pilot study looked at how closely 200 patients with advanced breast or prostate cancer follow their prescribed oral treatments. Participants filled out questionnaires about their medication use and gave blood samples to check certain health markers. The goal was to…

This study tested a new education program for 18 men with metastatic prostate cancer who were taking next-generation hormone therapy. The program was designed to help them better understand their disease, stick to their medication, and improve their quality of life. Researchers c…

This study looked at whether a simple blood test can predict which patients are more likely to have long-term side effects from radiation therapy. Researchers measured how well certain immune cells (CD8 T-cells) die after being exposed to radiation. The goal was to see if this te…

This early-phase study looked at whether giving a short, strong dose of flutamide (a hormone blocker) can create DNA breaks in prostate cancer cells in men already receiving standard hormone therapy and brachytherapy. The goal was to see if this approach could make cancer cells m…

This study looked at how men from different racial and ethnic backgrounds think about their genetic risk for prostate cancer. Researchers asked 100 men aged 40 and older who had never had prostate cancer to share their beliefs and provide a saliva sample for genetic testing. The …

This study surveyed 109 men with prostate cancer and women with breast cancer who were starting radiation therapy. Researchers asked about their use of nutritional supplements and complementary or alternative medicine (CAM) at three different times to see if their habits changed.…

This study looked at how often a specific gene change (HOXB13 c.853delT) occurs in men with prostate cancer in Martinique. Researchers tested 465 men of African descent to find the frequency of this mutation. The goal was to better understand genetic factors behind the high prost…

This study tested whether a patient navigator could help Black breast and prostate cancer patients complete a shorter course of radiation therapy. 30 African-American adults took part. Researchers used surveys to find out what barriers patients face and whether the navigator help…

This study looked at the safety of the cancer drug olaparib in over 1,000 Chinese patients with ovarian or prostate cancer. Researchers tracked side effects and how doctors managed them in everyday medical practice. The goal was to better understand the drug's real-world safety p…

This study compared two methods of taking a prostate biopsy: one through the rectal wall and one through the skin between the scrotum and anus. 840 men who needed a biopsy for suspected prostate cancer were randomly assigned to one of the two methods. The goal was to see which me…

This study looked at how prostate and colorectal cancer affect the energy-producing parts of cells (mitochondria) and whether a 4-week home exercise program could help. Fifteen men awaiting surgery did either resistance training or high-intensity interval training. Researchers me…

This study looked at 168 men with metastatic hormone-sensitive prostate cancer to see if a model using PSMA-PET scans and routine medical information could predict how well they would respond to standard first-line treatment. The researchers used existing scans and medical record…

This study tested an AI software called Quantib Prostate to see if it could find suspicious prostate cancer spots on MRI scans as accurately as expert radiologists. Researchers looked back at 200 men who had prostate MRIs and biopsies. The goal was to compare the AI's performance…

This study looked at whether a special website or two phone calls with a health coach could encourage more people with a personal or family history of certain cancers to get genetic testing. Over 800 adults who already completed a family health survey were randomly assigned to on…

This study analyzed medical records of over 6,400 prostate cancer patients to see who received a new treatment called 177Lu-PSMA-617 and how they fared. Researchers looked at patient traits, treatment patterns, and survival rates. The goal was to understand early real-world use o…

This study looked at 70 men with newly diagnosed intermediate or high-risk prostate cancer. Researchers used special PET scans and blood tests to see if they could better predict how aggressive the cancer is. The goal is to help doctors choose the most effective treatment for eac…

This study tested a new way to analyze prostate cancer cells from biopsy samples. Researchers used a special imaging technique to guide biopsies and then studied individual cells to find unique protein patterns. The goal was to see if this approach could better predict how a pers…

This study looked at 30 men with prostate cancer to understand why MRI and PSMA PET scans sometimes detect different tumors. Researchers analyzed stored tissue samples to see if these mismatched spots are harmless, aggressive, or a different type of cancer. The goal is to help do…

This study tested whether iPhones and Apple Watches can reliably collect health data from people with cancer. 49 adults undergoing cancer treatment wore an Apple Watch and used an iPhone for 4 months to track activity, fatigue, and thinking skills. The goal was to see if these de…

This study involved 22 men with prostate cancer who were scheduled for prostate removal surgery. Each participant received two different PET/CT scans using different tracers (68Ga-RM2 and 68Ga-PSMA-617) to see how well each tracer highlighted cancer cells. The goal was to compare…

This study tested a program for adults aged 65-90 who had breast, colorectal, or prostate cancer. A community health worker assessed their health and provided coaching to address issues often missed after cancer treatment. The goal was to see if this approach is practical and hel…

This study created a biobank—a collection of health data and biological samples—from 592 African American men in Florida who had prostate cancer. The goal was to learn whether smoking makes prostate cancer more aggressive. Participants filled out questionnaires and provided saliv…

This study tested whether a special 2D grid can improve the quality of cone-beam CT (CBCT) images used during radiation therapy for prostate, head/neck, and abdomen cancers. Researchers compared standard CBCT images with those taken using the new grid in 43 participants. The goal…

This study looked at whether a blood test can predict how prostate cancer responds to the drug abiraterone. Researchers collected blood samples from 40 men with advanced prostate cancer before and during treatment. They measured proteins in rare tumor cells found in the blood to …

This study looked at 382 men with low-grade prostate cancer to find clues that might predict if the cancer is actually more aggressive than it first appears. Researchers collected medical information and biological samples to build a risk prediction tool. The goal is to help doct…

This study looked at 185 men with low-risk prostate cancer who chose active surveillance (monitoring instead of immediate treatment). Researchers used a genetic risk score based on common DNA variants to see if it could predict when the cancer might progress. The goal is to help …

This study looked at how DNA from tumors changes in the blood before, during, and after cancer surgery. Thirty adults with breast, prostate, or colon cancer had blood samples taken to measure these DNA levels. The goal was to understand the natural changes, not to test a treatmen…

This early-phase pilot study tested whether giving rituximab (a drug that removes B cells) before prostate removal surgery could reduce B cell levels in the tumor. Eight men with high-risk prostate cancer participated. The main goal was to see if the drug changes the tumor's immu…

This study collected urine and blood samples from 80 men, including those with prostate cancer, those with suspected cancer, and healthy volunteers. The goal was to find new biomarkers (biological clues) that could help diagnose prostate cancer or predict how it will progress, wi…

This very small study with only 5 participants looked at whether special MRI scans can be used to adjust radiation treatment for high-risk prostate cancer. The goal was to see if the MRI method was reliable and could help target tumors more precisely. The study did not test a new…

This study followed 831 men aged 60 and older with prostate cancer who were starting hormone therapy (GnRH agonists). Researchers tracked how their quality of life changed over six months using questionnaires. The goal was to understand how different age groups cope with treatmen…

This study looked at whether teaching men with advanced prostate cancer about orchiectomy (surgery to remove the testicles) would make them more likely to choose it instead of staying on lifelong hormone therapy. 101 men who were already on hormone therapy for at least a year wer…

This study tested a digital tool (a chatbot) to help cancer survivors learn about genetic testing for hereditary cancer risk. 50 adults who had certain cancers (like breast, ovarian, or prostate) took part. The goal was to see if the chatbot was easy to use and if it helped more …

This study tested whether a special PET scan can measure low oxygen levels (hypoxia) in prostate cancer tumors. 18 adults with intermediate to high-risk prostate cancer received a tracer called FAZA before their standard treatment. The goal was to see if this imaging method is fe…

This study followed 25 men who carry BRCA1 or BRCA2 gene mutations, plus a control group, to see if they developed prostate cancer. Researchers called participants to update their health history and track new diagnoses. The goal is to help design better screening programs for men…

This study looked at gene activity in prostate tissue from 867 men to learn how certain gene patterns are linked to prostate cancer growth and patient outcomes. Participants were scheduled for biopsy or surgery for a prostate condition. The goal was to better understand the disea…

This study looked at 10 men to understand why androgen deprivation therapy (ADT) for prostate cancer can lead to high blood pressure. Researchers checked if problems with the nervous system or kidneys were to blame. The goal is to find ways to prevent heart disease in prostate ca…

This study looked at whether a special gel placed near the rectum can help doctors aim radiation more accurately for prostate cancer. Seventeen men who already had the gel and small metal markers were included. The goal was to see if the gel could replace the markers for daily al…

This study tested a program called KanSurvive-ECHO to help rural primary care clinics provide better follow-up care for cancer survivors. Researchers worked with 15 clinics to improve tasks like scheduling cancer screenings, checking for distress, and tracking weight and tobacco …

This study tested new guidelines for PSA screening in 49 men aged 40-75 with elevated PSA levels. The goal was to improve how doctors decide when to start and stop screening, how often to repeat it, and when to refer for biopsy. Researchers compared PSA test rates, biopsy complic…

This study looked at 33 men with advanced prostate cancer that no longer responds to hormone therapy. Researchers analyzed tiny molecules called microRNAs in blood and tissue samples to see if they could predict which patients would not benefit from chemotherapy or newer hormone …

This study looked at whether a new type of camera (CZT) can accurately measure the radiation from a prostate cancer drug called lutetium. Researchers used past images from 20 patients to compare different energy levels. The goal was to see if the camera gives reliable measurement…