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New hope for tough prostate cancer: drug shrinks PSA in many men

NCT ID NCT01171898

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 30 times

Summary

This study tested a new drug called ARN-509 in 127 men with advanced prostate cancer that had stopped responding to standard hormone therapy. The goal was to find a safe dose and see if the drug could lower PSA levels, a marker of cancer activity. The drug was given as a daily pill, and the study tracked how many men had a significant PSA drop after 12 weeks.

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Contacts and locations

Locations

  • Study site

    San Diego, California, United States

  • Study site

    San Francisco, California, United States

  • Study site

    Atlanta, Georgia, United States

  • Study site

    Baltimore, Maryland, United States

  • Study site

    Boston, Massachusetts, United States

  • Study site

    Ann Arbor, Michigan, United States

  • Study site

    Omaha, Nebraska, United States

  • Study site

    New York, New York, United States

  • Study site

    Raleigh, North Carolina, United States

  • Study site

    Portland, Oregon, United States

  • Study site

    Lancaster, Pennsylvania, United States

  • Study site

    Myrtle Beach, South Carolina, United States

  • Study site

    Dallas, Texas, United States

  • Study site

    Seattle, Washington, United States

  • Study site

    Madison, Wisconsin, United States

Conditions

Explore the condition pages connected to this study.