PROSTATE CANCER

This study tested a combination of two drugs—tivozanib and enzalutamide—in men with advanced prostate cancer that had stopped responding to standard hormone therapy. The goal was to see if adding tivozanib (which cuts off the tumor's blood supply) to enzalutamide could delay canc…

This early-stage study tested a new drug called acapatamab in 212 men with metastatic castration-resistant prostate cancer that had stopped responding to standard therapies. The drug works by helping the body's immune cells attack cancer cells that have a specific marker (PSMA) o…

This study tested the drug pacritinib in 6 men whose prostate cancer had returned after surgery or radiation, shown by rising PSA levels. The goal was to see if the drug could delay further PSA increases. The trial was terminated early, so results are limited.

This early-stage study tested whether a laser system guided by MRI and ultrasound images could safely treat prostate cancer. Only 2 men with early-stage prostate cancer took part before the study was stopped. The main goal was to check for serious side effects and see if the appr…

This study tested a new drug called NUV-868, alone or with other cancer drugs (olaparib or enzalutamide), in 82 adults with advanced solid tumors like ovarian, pancreatic, prostate, or breast cancer. The main goals were to check safety and find the right dose. The trial was stopp…

This study tested the drug cabozantinib in men with a type of advanced prostate cancer that no longer responds to hormone therapy. It focused on patients whose tumors had certain gene changes or had spread to the liver. The goal was to see if the drug could slow cancer growth, bu…

This study looked at whether a lower dose of the prostate cancer drug abiraterone can still control the disease. About 50 men with prostate cancer who were starting abiraterone for the first time took part. The goal was to find the smallest effective dose by measuring hormone lev…

This study tested an experimental immunotherapy called VTP-850 in 22 men whose prostate cancer had returned after initial treatment (surgery or radiation). The goal was to see if the treatment was safe and could lower PSA levels, a marker of cancer activity. The trial was termina…

This study tested a combination of two drugs, cabozantinib and abiraterone, in men with a type of advanced prostate cancer that had spread to the bones and no longer responded to standard hormone therapy. The goal was to see if the combination could delay cancer growth or death. …

This study looked at whether a drug called OPC could lower AGE levels in men with prostate cancer who are receiving hormone therapy (androgen deprivation therapy). AGEs are substances that can build up in the body and may cause health problems. The study planned to enroll 41 part…

This study tested whether a special MRI contrast agent called Ferumoxtran-10 can better find prostate cancer that has spread to nearby lymph nodes compared to standard MRI. It involved 172 men with newly-diagnosed prostate cancer who were scheduled for surgery. The results from t…

This study tested a technique that helps people with advanced cancer and their partners organize traumatic memories and practice slow breathing to reduce PTSD symptoms. The approach aimed to shift how the brain processes trauma, moving from emotional reactions to more controlled …

This study looked at whether giving only 2 MRI-guided radiation treatments is as good as 5 for men with low or intermediate-risk prostate cancer. The main goal was to see if fewer treatments cause similar or fewer bowel and urinary side effects. The study was stopped early, but i…

This study tested whether placing a special placental tissue over nerves during prostate removal surgery could help men recover erections and bladder control faster. Only 3 men with early-stage prostate cancer took part before the study was stopped early. The approach was experim…

This study tested a biodegradable balloon placed between the prostate and rectum to see if it could reduce radiation damage to the rectum during prostate cancer treatment. The study enrolled 24 men with intermediate-risk prostate cancer. The main goal was to measure how much the …

This study looked at whether an online video simulator helps surgeons learn a specific type of prostate cancer surgery (laparoscopic radical prostatectomy). It involved 29 surgeons who were new to the procedure. The main goal was to see if the simulator reduced surgery time and c…

This study aimed to see if a simple blood test could predict which men with prostate cancer might experience memory or thinking problems from hormone therapy (ADT). Researchers planned to follow 32 men over time, comparing those on ADT to those not on it. The study was terminated…

This study tested whether combining two types of advanced scans (PSMA-PET and MRI) could help doctors better target radiation for men with unfavorable-risk prostate cancer. Only 8 people took part before the study was stopped early. The main goal was to see if this approach was s…

This study looked at whether a special monitor (CardioQ-ODM+) could accurately predict when patients having robot-assisted prostate surgery need extra fluids. The surgery involves gas inflation and a head-down position, which can affect normal fluid measurements. The study enroll…