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Experimental drug combo tested for tough prostate cancer

NCT ID NCT00183937

First seen May 26, 2026 · Last updated Jun 21, 2026 · Updated 3 times

Summary

This study tested a combination of two drugs, bortezomib and docetaxel, in 15 men with advanced prostate cancer that had stopped responding to hormone therapy. The goal was to see if the drugs could lower PSA levels and ease pain. The trial was terminated early, so the findings are limited.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • USC/Norris Comprehensive Cancer Center

    Los Angeles, California, 90033, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

bortezomib (Velcade) and docetaxel

What this could lead to

If successful, this combination could offer a new treatment option for men with advanced prostate cancer that no longer responds to hormone therapy.

What could go wrong

This was a very small, early-phase trial that was terminated early, so results are limited. The combination may cause serious side effects and may not improve outcomes.

Conditions

The condition(s) this trial relates to.

hormone-resistant prostate carcinoma prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.