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Can retelling and deep breathing ease trauma in terminal cancer?

NCT ID NCT03652298

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase 2 trial tested a neuroscience-based technique combining memory structuring and deep vagal breathing to reduce PTSD symptoms in people with advanced, incurable cancer and their partners. The study enrolled 19 patients who had just received a terminal diagnosis. The approach aimed to help them process the traumatic news by organizing memories and using paced breathing to calm the nervous system. The trial was terminated early, so firm conclusions cannot be drawn.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Memory structuring intervention plus vagal breathing
What this could lead to
If it works, this could point toward a non-drug technique to reduce PTSD symptoms in people with advanced cancer.
What could go wrong
The trial was terminated early with only 19 participants, so results are very limited. It is unclear if the approach is effective or safe in this setting.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

19 people

The number who actually took part.

Started

Jul 2018

Finished

Jun 2020

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Men or women aged over 18 years old; * Who received in the last 7 days the diagnosis of metastatic incurable bladder, prostate, kidney, colorectal or sarcoma cancer (including recurrence) during the announcement visit; * Whose life expectancy is estimated ≥ 6 months by their treating oncologist; * Who have a WHO performance score \< 3 (to be coherent with the life expectancy); * Who have an albumin level \> 30g/liter (patients with an acceptable state of nutrition); * Who gave their signed consent to participate in the study; * Who are covered by a social insurance. Exclusion Criteria: * Patients diagnosed with cerebral metastases; * Patients with locally advanced cancer without metastases; * Patients with an advanced or metastatic cancer amenable to curative intent treatment; * Patients suffering from a psychological vulnerability that might alter their reasoning or judgment capacities; * Patients with a psychological or physical incapacity to answer the questionnaires, attested by the medical staff; * Patients under custodial sentence or under tutelage or protection of vulnerable adults

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre Oscar Lambret

    Lille, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.