Centre Hospitalier Universitaire De Nīmes
Clinical trials sponsored by Centre Hospitalier Universitaire De Nīmes, explained in plain language.
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New artery-blocking technique shows promise for low-risk prostate cancer
Disease control CompletedThis small pilot study tested a procedure called prostatic arterial embolization in 10 men with low-risk prostate cancer that was only on one side of the prostate. The idea was to cut off blood supply to the tumor, causing it to shrink or stop growing. The study looked at safety …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated May 17, 2026 01:51 UTC
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Dialysis showdown: citrate vs heparin for bleeding risk patients
Disease control CompletedThis study tested two ways to prevent blood clots during dialysis in 60 patients who were at risk of bleeding. One method used a substance called citrate, the other used a low dose of heparin. The goal was to see which approach allowed dialysis to last longer and caused fewer ble…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated May 17, 2026 01:50 UTC
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Double-Team tech boosts colon polyp detection in new study
Disease control CompletedThis study compared three ways to find precancerous polyps during colonoscopy: using an AI system alone, a special cap alone, or both together. About 481 adults undergoing screening took part. The goal was to see if the combination finds more polyps than either method by itself, …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated May 17, 2026 01:50 UTC
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New hope for endometriosis patients: could a simple pill protect fertility as well as standard shots?
Disease control CompletedThis study looked at whether a hormone pill called dienogest works as well as standard hormone injections for collecting eggs in women with endometriosis who want to preserve their fertility. Researchers compared the number of mature eggs collected from 130 women using either die…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated May 17, 2026 01:49 UTC
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Does triggering ovulation improve IVF success? new study investigates
Disease control CompletedThis study looked at 103 women undergoing frozen embryo transfer to see if letting them ovulate naturally or using a hormone shot (HCG) to trigger ovulation leads to more pregnancies. The goal was to find out which approach gives a better chance of getting pregnant. Results will …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated May 17, 2026 01:48 UTC
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Daily ultrasound could keep heart failure patients out of the hospital
Disease control CompletedThis study tested whether daily bedside ultrasound helps doctors better adjust treatment for people hospitalized with acute heart failure. The goal was to reduce the number of patients readmitted within 30 days. The study involved 250 adults with heart failure and low heart funct…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated May 17, 2026 01:47 UTC
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Could a tiny dose of IL-2 tame ALS?
Disease control CompletedThis study tested whether a low dose of interleukin-2 (IL-2), a protein that helps regulate the immune system, is safe and can increase regulatory T cells in people with ALS. 36 participants received either IL-2 or a placebo for five days. The goal was to see if this approach cou…
Phase: PHASE2 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated May 17, 2026 01:46 UTC
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Home pharmacy visits may cut COPD attacks
Disease control CompletedThis study looked at whether having a pharmacist talk with people in their homes could reduce the number of COPD flare-ups. 174 adults with moderate to severe COPD took part. The goal was to see if these consultations help patients manage their condition better and avoid worsenin…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated May 17, 2026 01:45 UTC
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Can vitamin d boost heart health in obese teens?
Disease control CompletedThis study looked at whether adding vitamin D supplements to a healthy lifestyle program could improve blood vessel function in obese teenagers. 49 teens participated over 3 months. The main goal was to see if vitamin D helped blood vessels relax and work better, which is importa…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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Which filter cleans blood better? study tests two dialysis methods for ICU patients
Disease control CompletedThis study looked at 163 intensive care patients with sudden kidney failure to compare two blood-filtering techniques: hemodiafiltration and hemofiltration. The main goal was to see which method better reduces waste products like urea in the blood after 12 hours. Results help doc…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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Could a tiny dose of IL-2 slow ALS? new trial results are in
Disease control CompletedThis phase II trial tested whether low-dose interleukin-2 (IL-2) can safely slow the progression of ALS, a severe nerve disease. Over 300 newly diagnosed patients received either the drug or a placebo for 18 months. The goal was to see if boosting certain immune cells could reduc…
Phase: PHASE2 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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New scanner sees fractures with far less radiation
Diagnosis CompletedThis study compared a new ultra low-dose CT scanner to standard X-rays for finding broken bones in the back, pelvis, arms, and legs. 554 emergency room patients with suspected fractures were scanned with both methods. The goal was to see if the low-dose scanner could detect fract…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated May 17, 2026 01:44 UTC
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PET scan may help spot brain tumors vs. Look-Alike lesions
Diagnosis CompletedThis study looked at whether a type of PET scan (FDOPA-PET) can help doctors tell the difference between brain tumors and non-cancerous brain lesions. Researchers analyzed scans from 74 patients with suspected brain tumors. The goal was to find patterns in the scan that best sepa…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated May 15, 2026 11:57 UTC
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New french test aims to spot delirium in seniors faster
Diagnosis CompletedThis study tested a French version of the Confusion Assessment Method (CAM), a tool to diagnose sudden confusion (delirium) in elderly patients. Researchers compared the CAM results with a psychiatrist's diagnosis using standard criteria. The goal was to see how accurate the Fren…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated May 15, 2026 11:57 UTC
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Which test spots brain fog in drinkers best? study pits MoCA vs BEARNI
Diagnosis CompletedThis study compared two short screening tests (MoCA and BEARNI) to see which one better detects thinking and memory problems in people with alcohol use disorder. Researchers tested 90 patients and checked the results against a full set of detailed brain tests. The goal was to fin…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated May 15, 2026 11:54 UTC
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Grinding up samples: a better way to spot bone infections?
Diagnosis CompletedThis study tested two ways of preparing tissue samples to find bacteria in bone and joint infections. One method grinds the sample, the other uses standard techniques. Researchers wanted to see which method is better at detecting infection. 122 people with suspected infections to…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated May 15, 2026 11:54 UTC
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Blood test may spot dangerous headaches in the ER
Diagnosis CompletedThis study looked at whether measuring a protein called S100B in the blood can help emergency doctors tell the difference between common headaches (like migraines) and headaches caused by a more serious problem (like bleeding or infection). 81 adults with bad headaches but no rec…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated May 14, 2026 12:05 UTC
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Simple blood test after thyroid surgery could spare patients unnecessary worry
Diagnosis CompletedThis study looked at 300 patients who had their thyroid gland removed. Doctors measured their parathyroid hormone (PTH) levels right after surgery to see if a low level could predict dangerously low calcium (hypoparathyroidism). The goal was to find a cutoff value that reliably r…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated May 14, 2026 12:03 UTC
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Blood test may predict kidney danger in muscle breakdown patients
Diagnosis CompletedThis study looked at 197 emergency room patients with rhabdomyolysis (severe muscle breakdown) to see if a blood marker called NGAL can predict acute kidney failure within 48 hours. Researchers measured NGAL levels and tracked kidney outcomes. The goal is to find a faster way to …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated May 14, 2026 12:02 UTC
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Pharmacist intervention boosts pneumonia vaccine rates in At-Risk patients
Prevention CompletedThis study looked at whether a clinical pharmacist could help increase pneumococcal vaccination rates in patients at high risk for infection before they leave the hospital. Researchers enrolled 167 adults who were not up-to-date on their vaccines. The goal was to see if the pharm…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Prevention
Last updated May 15, 2026 11:57 UTC
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Cranberry capsules tested to stop catheter infections after surgery
Prevention CompletedThis study tested whether cranberry gel capsules can prevent E. coli infections in patients who have a urinary catheter placed during pelvic surgery. The researchers wanted to see if cranberry's natural properties could stop bacteria from sticking to the catheter. 270 adults took…
Phase: PHASE2 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Prevention
Last updated May 15, 2026 11:54 UTC
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Hospital pharmacists boost lifesaving vaccine rates in vulnerable patients
Prevention CompletedThis study tested whether a pharmacist-led program could increase pneumococcal vaccination rates in patients at high risk for serious infections. Over 600 hospitalized adults with conditions like chronic disease or weakened immune systems took part. The pharmacist reviewed their …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Prevention
Last updated May 12, 2026 13:40 UTC
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Robot or not? new study compares surgery methods for pelvic organ prolapse
Symptom relief CompletedThis study looked at 365 women with pelvic organ prolapse (when organs like the bladder or uterus slip out of place) to compare two surgical repair methods: robot-assisted and standard laparoscopic surgery. The main goal was to see which approach had fewer complications within 30…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 17, 2026 01:50 UTC
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Laughing gas may help frozen shoulder patients move better
Symptom relief CompletedThis study looked at whether breathing a mix of oxygen and nitrous oxide (sometimes called laughing gas) during physical therapy helps people with frozen shoulder. 75 adults with frozen shoulder took part. The goal was to see if the gas reduces pain and improves shoulder movement…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 17, 2026 01:49 UTC
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Could HIV drugs clear psoriasis? small study explores new approach
Symptom relief CompletedThis study tested whether drugs that block reverse transcriptase (normally used for HIV) could help treat psoriasis. The idea was that these drugs might reduce inflammation by targeting DNA loops in skin cells. Eight adults with plaque psoriasis took part, and researchers checked…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 17, 2026 01:49 UTC
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Electric hand device helps stroke survivors regain grip
Symptom relief CompletedThis study tested a hand device that uses mild electrical pulses to help stroke survivors open their hand and grasp objects like a glass or spoon. Eleven people with chronic hand paralysis after a stroke participated. The goal was to see if the device improved their ability to pi…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 17, 2026 01:48 UTC
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Mind games may help heart patients pedal harder
Symptom relief CompletedThis study tested whether a technique called evaluative conditioning could help people who had a heart attack exercise more intensely during cardiac rehab. Twenty-four patients were split into two groups: one received conditioning linked to physical activity, the other to diet. T…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 17, 2026 01:47 UTC
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Ketamine shows promise for rapid relief of suicidal ideation
Symptom relief CompletedThis study tested whether ketamine, given as two infusions, can quickly reduce suicidal thoughts in 156 patients hospitalized for suicide risk. The main goal was to see if suicidal ideas resolved within 24 hours after the second dose. The approach aims to provide fast, short-term…
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 17, 2026 01:45 UTC
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New injection technique for knee pain shows promise in early trial
Symptom relief CompletedThis study tested a new way to inject medicine for knee pain caused by degenerative meniscal tears. 70 adults received either a standard joint injection or an injection directly into the meniscal wall, guided by ultrasound. The goal was to see if the new method provides better pa…
Phase: PHASE1 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 17, 2026 01:44 UTC
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Smart angel device aims to keep surgery patients safe at home
Symptom relief CompletedThis study tested a device called SMART ANGEL that tracks heart rate, blood pressure, oxygen levels, and symptoms like pain or nausea after outpatient surgery. About 1,260 adults used the device at home to see if it reduced unplanned hospital visits, doctor calls, or extra prescr…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 15, 2026 11:56 UTC
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Which breathing tube causes the least pain? study compares three devices
Symptom relief CompletedThis study tested three different breathing devices used during short surgeries to see which one causes the least sore throat afterward. Over 500 adults took part, and researchers measured pain, how easy the device was to place, and how many tries it took. The goal is to find the…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 15, 2026 11:56 UTC
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One-Side artery block may be enough for prostate relief
Symptom relief CompletedThis study looked at 50 elderly men with enlarged prostates who needed a long-term urinary catheter. Doctors compared blocking the prostate arteries on one side versus both sides to see if one side alone could allow catheter removal. The goal was to reduce discomfort and infectio…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 15, 2026 11:56 UTC
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Hypnosis or laughing gas? study tests best pain relief for kids getting stitches
Symptom relief CompletedThis study tested two ways to manage pain in children getting stitches in the emergency room: a gas called MEOPA (a mix of nitrous oxide and oxygen) versus hypnosis (with MEOPA available if needed). Sixty children took part. The goal was to see which approach better controlled pa…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 15, 2026 11:55 UTC
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Virtual reality mirror trick shows promise for rare pain condition
Symptom relief CompletedThis study tested a new therapy using augmented reality (AR) to help people with Complex Regional Pain Syndrome (CRPS) in their arm or hand. Seven patients tried AR mirror therapy along with standard physical and occupational therapy. The goal was to see if it improves arm moveme…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 15, 2026 11:53 UTC
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New combo aims to cut morphine use after colon surgery
Symptom relief CompletedThis study looked at whether adding a drug called nefopam to the usual painkiller (morphine) helps people use less morphine after major colon surgery. 80 adults having planned surgery for colon cancer or diverticulosis took part. The main goal was to measure how much morphine the…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 14, 2026 12:04 UTC
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Heart rate drug tested in emergency intubation
Symptom relief CompletedThis study tested whether giving a drug called remifentanil during emergency breathing tube placement can prevent a dangerously fast heart rate. 75 fragile patients who needed rapid intubation were included. Researchers compared two different doses of remifentanil to see which wo…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 14, 2026 12:03 UTC
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New anesthesia combo may ease Post-Surgery pain for hand operations
Symptom relief CompletedThis study tested two ways of numbing the arm for hand, wrist, or elbow surgery to see which one reduces pain after the procedure. 91 adults having outpatient surgery received either lidocaine alone or lidocaine plus ropivacaine. The goal was to find which approach gives better p…
Phase: PHASE1 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 13, 2026 16:02 UTC
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Can a simple injection ease menopause pain? new study says maybe
Symptom relief CompletedThis small study tested whether injecting a gel-like substance (hyaluronic acid) into the vaginal area could help menopausal women with pain during sex. Twenty women received the injections and were followed for 8 weeks. The main goal was to see if the vaginal lining thickened, w…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 13, 2026 16:01 UTC
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Back surgery pain relief: simple nerve block cuts morphine use
Symptom relief CompletedThis study tested whether a nerve block (erector spinae block) could reduce pain and the need for morphine after lumbar spine surgery. Fifty adults having lower back surgery received either the nerve block or a placebo. The goal was to see if the block provides better pain contro…
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 13, 2026 16:00 UTC
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New painkiller may cut side effects after hip surgery
Symptom relief CompletedThis study tested if a painkiller called oxycodone causes fewer side effects than morphine after hip replacement surgery. 246 adults were given one of the two drugs to control pain right after their operation. The goal was to see if oxycodone could reduce problems like nausea, vo…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 13, 2026 15:58 UTC
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New wheelchair adapts to spasms, could improve comfort
Symptom relief CompletedThis study tested a special wheelchair (NETTI) that can switch between a dynamic mode (moving with the person) and a static mode (locked in place). Four people with frequent involuntary muscle spasms that cause them to slide forward in their chair took part. Researchers measured …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 12, 2026 13:39 UTC
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Heart attack recovery gets a buddy system: study tests patient partners to keep you moving
Symptom relief CompletedThis study looked at whether having a 'patient partner' (a fellow heart attack survivor) work with a healthcare professional can help people stay physically active after completing cardiac rehab. 84 adults who had a heart attack and finished phase 2 rehab were split into two grou…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 12, 2026 13:39 UTC
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Mental health risks explored in women with pregnancy loss condition
Knowledge-focused CompletedThis study looked at how common major psychiatric disorders are in women with antiphospholipid syndrome (a condition that can cause blood clots and pregnancy loss) compared to women with similar pregnancy loss histories but without the syndrome. Researchers evaluated over 1,500 w…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:59 UTC
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Hospital pharmacist study aims to cut errors and costs
Knowledge-focused CompletedThis study tested whether having a clinical pharmacist work with doctors in two hospital units (infectious disease and internal medicine) could improve the quality of care and lower costs. The researchers tracked medication errors, how well prescriptions matched best practices, a…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:52 UTC
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New CT technique could slash radiation in bone scans without losing clarity
Knowledge-focused CompletedThis study tested whether a newer CT reconstruction method (ASIR) can produce clear bone SPECT images using very low radiation doses, compared to the standard method (FBP) with low doses. 75 adults scheduled for a SPECT-CT scan took part. The goal was to see if image quality stay…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:52 UTC
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Could a Pre-Surgery blood vessel block boost colon healing?
Knowledge-focused CompletedThis small pilot study tested whether blocking the inferior mesenteric artery with tiny particles 3-4 weeks before rectal or sigmoid colon cancer surgery helps the colon develop better blood flow. Ten adults with rectal or sigmoid cancer took part. The goal was to see if this pre…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:52 UTC
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Brain scans may reveal clues to mysterious movement disorder
Knowledge-focused CompletedThis study looked at 20 people with a first episode of motor conversion disorder, a condition where psychological stress causes physical symptoms like paralysis or weakness. Researchers used PET scans to check for unusual brain activity at the start and then tracked whether sympt…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:51 UTC
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ICU kidney study seeks sweet spot for fluid removal
Knowledge-focused CompletedThis study looked at 39 intensive care patients with acute kidney failure who needed dialysis to remove excess fluid. Researchers tested three different fluid removal rates to see which one caused the fewest drops in blood pressure while still effectively removing fluid. The goal…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:51 UTC
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Arm position may help doctors find veins easier
Knowledge-focused CompletedThis study looked at 50 healthy adults to see if changing arm position makes veins in the armpit and collarbone area show up larger on ultrasound. Participants had their veins measured with their arm by their side and with their arm raised and rotated. The goal is to help doctors…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:51 UTC
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CRPS Patients' brain imagery under the microscope
Knowledge-focused CompletedThis study looked at whether people with Complex Regional Pain Syndrome (CRPS) have trouble imagining movements in their mind. Researchers compared 129 adults—some with CRPS, some with other muscle pain, and some healthy—using a questionnaire that measures motor imagery skills. T…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:51 UTC
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Blood marker may foretell COVID-19 survival
Knowledge-focused CompletedThis study looked at whether a blood test marker called NEU-SFL, which reflects immune cell activity, can help predict the risk of death in people hospitalized with COVID-19 in 2021. Researchers compared NEU-SFL levels between those who survived and those who did not. The goal wa…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:51 UTC
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Hidden danger: abuse may double blood clot risk for women on the pill
Knowledge-focused CompletedThis study looked at whether intimate partner violence (IPV) increases the risk of blood clots in women taking birth control pills. Researchers compared 997 women who had a first blood clot with similar women who did not. They used a questionnaire to measure IPV exposure. The goa…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:51 UTC
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Immune clues could predict diabetes risk in seniors
Knowledge-focused CompletedThis study examined 158 adults aged 55-69 to see if certain immune system markers are linked to insulin resistance, a condition that can lead to diabetes. Researchers measured various immune cells and other blood markers to find patterns that might help identify people at risk. T…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:51 UTC
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Brain scans may predict drug success in aggressive cancer
Knowledge-focused CompletedThis study looked at whether special brain scans (PET and CT perfusion) can predict if the drug bevacizumab will work in people whose glioblastoma brain cancer has come back. Fourteen patients were scanned before treatment to see if the scans could tell who would respond. The goa…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:50 UTC
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Ultrasound vs. touch: which works better for tough blood draws?
Knowledge-focused CompletedThis study tested whether using ultrasound to locate the radial artery (in the wrist) makes blood draws easier for patients whose arteries are hard to feel or where previous attempts failed. 74 adults were randomly assigned to have their blood drawn either with ultrasound guidanc…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:50 UTC
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New needle guide may make ICU line placement faster and safer
Knowledge-focused CompletedThis study tested a new needle-steering device to help doctors insert central lines (large IVs) into a major vein below the collarbone. In a mannequin simulation, the device helped doctors succeed on the first try more often, with fewer needle sticks and less time. The next step …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:50 UTC
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New study aims to improve emergency care for serious belly infections
Knowledge-focused CompletedThis study looked at 200 adults who came to the emergency room with a serious abdominal infection that needed surgery. Researchers wanted to find out what factors lead to delays in proper treatment, which can cause worse outcomes. By collecting data on how these infections are ma…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:50 UTC
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New french tool helps understand how patients perceive their back pain
Knowledge-focused CompletedThis study tested a French version of the Fremantle Back Awareness Questionnaire (FreBAQ) in 150 people with chronic low back pain. The questionnaire measures how patients perceive their back and its movements. The goal was to confirm that the French version works as well as vers…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:50 UTC
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Quick tests reveal hidden infections in detention centers
Knowledge-focused CompletedThis study aimed to find out how many people held at the Nîmes administrative detention center have HIV, hepatitis B, or hepatitis C. Researchers used rapid tests to get results quickly, since many detainees leave before standard lab results come back. A total of 350 detainees to…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:50 UTC
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New education program aims to help men with advanced prostate cancer better understand their treatment
Knowledge-focused CompletedThis study tested a new education program for men with metastatic prostate cancer who are taking next-generation hormone therapy. The program was designed to help patients learn more about their disease, stick to their medication, and improve their quality of life. The study invo…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:50 UTC
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Blood markers may reveal hidden cancer spread in polyp patients
Knowledge-focused CompletedThis study explored whether intestinal polyps release tumor cells or other substances into the blood that could signal early cancer spread. Researchers compared blood samples from 120 people with and without polyps. The goal was to find new biomarkers to improve monitoring and gu…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:50 UTC
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Blood markers may forecast pregnancy risks in autoimmune disorder
Knowledge-focused CompletedThis study looked at 513 women with antiphospholipid syndrome starting a new pregnancy. Researchers measured two blood markers (PGF and sFlt1) before and after the first heparin injection to see if they could predict serious pregnancy complications like preeclampsia, placental ab…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:49 UTC
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Does poverty predict late breast cancer diagnosis?
Knowledge-focused CompletedThis completed study looked at 684 people with breast cancer to see if those with unstable living conditions (social fragility) are more likely to be diagnosed at a later, harder-to-treat stage. Researchers compared early-stage (good prognosis) and late-stage (poor prognosis) cas…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:49 UTC
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Scientists hunt for biological clues in mysterious movement disorder
Knowledge-focused CompletedThis study looked at 20 adults experiencing their first episode of conversion disorder (also called functional neurological disorder), a condition where people have motor symptoms like weakness or abnormal movements without a clear neurological cause. Researchers measured inflamm…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:49 UTC
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Immune cell study aims to unlock secrets of childhood rash disease
Knowledge-focused CompletedThis study examined whether children with Henoch Schönlein Purpura (HSP) have problems with a type of immune cell called regulatory T cells. Researchers compared blood samples from 100 children with HSP to healthy controls. The goal was to better understand the disease, not to te…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:49 UTC
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Brain scan study reveals key differences in two common small vessel diseases
Knowledge-focused CompletedThis study looked at brain scans from 315 people with two different types of small vessel disease: cerebral amyloid angiopathy (CAA) and hypertensive arteriopathy (HA). Researchers wanted to see if the pattern of white matter changes around the brain's fluid-filled spaces could h…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:49 UTC
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Healthy volunteers help doctors understand vein behavior during breathing
Knowledge-focused CompletedThis study looked at 52 healthy adults to see how much the inferior vena cava (a large vein) collapses when they breathe. Researchers used ultrasound to measure the vein's diameter during inhaling and exhaling. The goal was to find a breathing-related measurement that best predic…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:49 UTC
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Life after prostate cancer: how do patients really feel 3 years later?
Knowledge-focused CompletedThis study looked at the quality of life of 900 men who were diagnosed with prostate cancer 3 years earlier, comparing them to men of the same age without cancer. The goal was to see if patients had returned to a "normal" life. Researchers used a standard questionnaire to measure…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:49 UTC
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New clues in spinal fluid may predict MS years before symptoms
Knowledge-focused CompletedThis study looked at 100 people who have brain changes seen on MRI but no MS symptoms yet (called radiologically isolated syndrome). Researchers measured four substances in their spinal fluid and blood to see if any could predict who later develops multiple sclerosis. The goal is…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:49 UTC
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Fasting before surgery: safe or risky?
Knowledge-focused CompletedThis study looked at whether not eating before surgery (preoperative fasting) causes low blood volume. 100 patients scheduled for gynecological or visceral surgery had their blood volume checked with an echocardiogram before and after fasting. The goal was to see if fasting incre…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:49 UTC
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Nose bacteria linked to foot infections in diabetics
Knowledge-focused CompletedThis study looked at whether the same staph bacteria found in the nose can also infect foot sores in people with diabetes. Researchers compared the genetic fingerprints of bacteria from both places in 278 patients. The goal was to understand the risk and improve detection, not to…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:49 UTC
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Blood protein clues could predict pregnancy dangers
Knowledge-focused CompletedThis study measured certain proteins (histones and HMGB1) in the blood of 115 pregnant women, some with placental complications like pre-eclampsia and some without. The goal was to see if these proteins could serve as early markers for such complications. No treatment was given; …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:49 UTC
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Shock treatment danger: high norepinephrine doses linked to death risk
Knowledge-focused CompletedThis study looked at 100 ICU patients with circulatory shock who received norepinephrine, a drug that raises blood pressure. Researchers wanted to find if a certain dose of norepinephrine is linked to a higher risk of death within 5 days. They also studied how long patients were …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:49 UTC
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Patient surveys could cut chemo waste, study finds
Knowledge-focused CompletedThis study looked at whether having patients report their symptoms online could give doctors enough information to decide if chemotherapy should be prepared, instead of requiring an in-person exam. 138 adults with digestive cancer who were already on chemotherapy participated. Th…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:48 UTC
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Ultrasound battle: which vein is best for central lines?
Knowledge-focused CompletedThis study tested two methods for inserting a central venous catheter (a large IV in the neck or chest) using real-time ultrasound. 210 adults who needed this catheter were randomly assigned to get it in either the lower jugular vein or the subclavian vein. The goal was to see ho…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:48 UTC
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Hidden diabetes complication exposed: charcot foot care under the microscope
Knowledge-focused CompletedThis study gathered information from over 1,100 diabetic patients with Charcot foot, a rare but serious complication that can lead to foot ulcers and amputation. Researchers in France and Belgium looked at how doctors currently diagnose and treat this condition, since there are n…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:48 UTC
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Can rehab get back pain patients moving more and sitting less?
Knowledge-focused CompletedThis study followed 89 adults with chronic low back pain who joined a rehabilitation program. Researchers wanted to see if the program helped them become more physically active, sit less, and change their motivation for exercise. The goal was to understand what drives these behav…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:47 UTC
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Vaccine side effect mystery: scientists investigate immune cell changes
Knowledge-focused CompletedThis study looked at how mRNA COVID-19 vaccines change the activity of certain immune cells (monocytes) in people of different ages. Researchers measured oxygen-related molecules produced by these cells before and after vaccination. The goal was to understand the body's response …
Phase: EARLY_PHASE1 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:47 UTC
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Which workout is best for your heart after a heart attack?
Knowledge-focused CompletedThis study looked at 100 people who had a heart attack and compared two exercise programs: steady moderate exercise versus short bursts of high-intensity exercise with rest periods. The goal was to see which type better improves the heart's ability to squeeze and relax, measured …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:47 UTC
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Ultrasound-Guided nerve testing may reduce pain for patients
Knowledge-focused CompletedThis study tested whether using ultrasound to find the best spot for nerve stimulation during electroneuromyography (a test that measures nerve and muscle activity) could lower the electrical intensity needed. Lower intensity may make the test more comfortable for patients. The t…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:47 UTC
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French ICUs see more severe cases yet deaths drop
Knowledge-focused CompletedThis study looked at over 1.5 million adults admitted to French intensive care units (ICUs) between 2013 and 2019. Researchers wanted to understand trends in patient numbers, how sick they were, how long they stayed, and death rates. They found that while patients were more criti…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:47 UTC
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Heart map may predict ablation success
Knowledge-focused CompletedThis study tested whether a special heart map (isochron map) can predict if atrial fibrillation returns after radiofrequency ablation. Researchers followed 175 adults with atrial fibrillation for 18 months after the procedure. The goal was to see if the map could identify who wou…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:46 UTC
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Scientists probe immune overreaction in severe COVID-19 to find new clues
Knowledge-focused CompletedThis study looked at 120 hospitalized COVID-19 patients with severe breathing problems to understand how their immune systems were reacting. Researchers measured many immune markers in the blood to see if a specific immune pattern could predict who might die. The goal was to find…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:46 UTC
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Thirst-Guided hydration may keep Ultra-Runners safer
Knowledge-focused CompletedThis study followed 198 runners in the 2015 Ultra-Trail du Mont-Blanc to see if drinking only when thirsty ("at thirst") helps maintain normal blood sodium levels compared to other hydration methods. The goal was to understand how different drinking strategies affect sodium balan…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:46 UTC
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Can a simple score better predict dangerous clots in hospitalized patients?
Knowledge-focused CompletedThis study looked at whether a common tool called the Wells score can accurately predict deep vein thrombosis (a type of blood clot) in hospitalized patients, especially those already taking blood thinners. Researchers compared the score's performance between specialists and gene…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:46 UTC
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New test may help doctors pick the right antibiotic for diabetic foot wounds
Knowledge-focused CompletedThis study looked at a new lab test called Antibiofilmogramme for people with diabetic foot infections caused by Staphylococcus aureus bacteria. The test checks how well different antibiotics can kill bacteria that form a protective slime layer (biofilm). Researchers wanted to se…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:46 UTC
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Robot vs. no robot: which trains surgeons better?
Knowledge-focused CompletedThis study tested whether using a robot helps surgical interns learn a key procedure faster. 34 interns were split into two groups: one trained with robotic assistance and one without. They were timed while performing a kidney removal (nephrectomy) on a pig model. The goal was to…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:45 UTC
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Blood test showdown: which detects melanoma cells better?
Knowledge-focused CompletedThis study compared two blood test methods (EPISPOT and CellSearch) for finding circulating melanoma cells in people with advanced melanoma. Researchers took blood samples from 73 participants, including patients with stage 4 melanoma and hospitalized controls without cancer. The…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:45 UTC
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New device aims to cut spine screw errors in half
Knowledge-focused CompletedThis study tested a new device called PYTHEAS ODYSSEE that helps surgeons place screws in the spine more accurately. Poorly placed screws can cause serious problems like bleeding or paralysis. The device uses a patient's CT scan to plan screw placement and then guides the surgeon…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:44 UTC
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Rare stroke cause mapped in new study
Knowledge-focused CompletedThis study looked at 79 people with a rare type of stroke caused by small calcium deposits traveling to the brain. Researchers used CT scans to describe the size, location, and source of these deposits. The goal was to better understand this condition, not to test a new treatment…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:44 UTC
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ER doctors' race bias in pain meds for sickle cell patients under microscope
Knowledge-focused CompletedThis study asked over 1,000 emergency doctors in Europe what they would prescribe for a patient with severe belly pain. The goal was to see if a patient's race influences whether doctors give morphine. The study did not involve actual patients, but used a made-up case to uncover …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:44 UTC
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Colostomy patients share their irrigation habits in major survey
Knowledge-focused CompletedThis study surveyed over 1100 adults with a colostomy to find out how often they use colon irrigation (a way to clean the bowel) and how it affects their daily life. Researchers compared quality of life between those who irrigate and those who don't, and looked at reasons for not…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:44 UTC
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Can a simple distraction change how people with back pain walk?
Knowledge-focused CompletedThis pilot study looked at how people with chronic low back pain walk and whether a distraction task could change their walking pattern and reduce pain. 16 adults with long-term back pain walked at their normal speed and a faster speed, with and without a distraction. The goal wa…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 01:44 UTC
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New sensor could help stroke patients walk better
Knowledge-focused CompletedThis study tested a small, wearable sensor (FOX HiKoB) to see how well it measures foot movement in people who have had a stroke. The goal was to compare the sensor to a standard motion-capture system. 29 stroke survivors who could walk with some help participated. The results wi…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC
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Timing is everything: fluid check delays may mislead septic shock care
Knowledge-focused CompletedThis study looked at 145 people with septic shock who received a standard fluid infusion over 10 minutes. Researchers wanted to see if checking the response right after the infusion versus waiting 20 minutes changed whether patients were labeled as "responders." The goal was to u…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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COVID-19 blood clot mystery: new study aims to uncover why
Knowledge-focused CompletedThis study looked at 175 hospitalized COVID-19 patients to understand why they develop dangerous blood clots. Researchers measured how quickly their blood forms clots using a special test. The goal was to find links between clotting problems and survival, which could help guide f…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Pregnancy cell secrets revealed: study probes inner workings
Knowledge-focused CompletedThis study looked at how cells in the placenta recycle parts (autophagy) and die (apoptosis) during pregnancy. Researchers measured these processes in 97 pregnant women, including those with normal pregnancies and those at risk for complications. The goal was to understand how th…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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New therapies for Women's pelvic pain under the microscope
Knowledge-focused CompletedThis study looked at 173 women with pelvic-perineal issues (like prolapse, incontinence, or pain) that didn't improve with standard treatments. Researchers observed the use of newer therapies such as LED light, radiofrequency, laser, and hyaluronic acid injections. The goal was t…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Brain scans reveal how stroke survivors recover movement
Knowledge-focused CompletedThis study looked at how the brain reorganizes itself in the first two months after a stroke. Ten participants had their brain activity measured using a non-invasive light-based technique called fNIRS while performing motor tasks. The goal was to create models linking brain chang…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Hidden mutations may drive blood clots in older adults
Knowledge-focused CompletedThis study checked 150 adults over 50 with a history of venous thromboembolism (blood clots) for certain genetic mutations in their blood cells. The goal was to see if these mutations, known as clonal hematopoiesis of indeterminate potential (CHIP), are common in this group. Rese…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC
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ER ultrasound study checks if two doctors see the same thing
Knowledge-focused CompletedThis study looked at whether two different doctors can get the same measurement of the diaphragm (the main breathing muscle) using ultrasound in patients who come to the emergency room with severe breathing trouble. 26 adults with acute respiratory distress took part. The goal wa…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC
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ICU antibiotic levels under the microscope
Knowledge-focused CompletedThis study looked at whether antibiotics given to critically ill patients reach high enough levels in the blood to kill bacteria effectively. Researchers measured drug concentrations in 98 ICU patients and compared them to targets known to work best. The goal was to understand cu…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC
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Personalized diet advice tested for MS patients
Knowledge-focused CompletedThis study looked at whether personalized dietary advice from a dietitian helps people with multiple sclerosis (MS) increase their calcium intake compared to just receiving a standard information sheet. A total of 182 MS patients who could walk and had never had a diet consultati…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC
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Gut bacteria linked to new arthritis diagnosis?
Knowledge-focused CompletedThis study looked at the gut bacteria of 55 people—some newly diagnosed with rheumatoid arthritis and some without the condition. Researchers wanted to see if certain bacteria were more common in those with arthritis. No treatments or medications were tested; the goal was simply …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC
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Pandemic's hidden toll: 7 in 10 ICU staff show PTSD symptoms
Knowledge-focused CompletedThis study looked at how working in intensive care during the COVID-19 outbreak affected the mental health of doctors, nurses, and other caregivers. Over 700 healthcare workers answered surveys about post-traumatic stress, anxiety, depression, and burnout. The goal was to underst…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC
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New blood test tech helps ICU patients get the right antibiotic faster
Knowledge-focused CompletedThis study looked at whether using three new lab technologies could help doctors choose the best antibiotic faster for ICU patients with a serious bloodstream infection. Researchers compared how often patients got the right antibiotic within 24 hours before and after the new tool…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC
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New questionnaire could help predict falls in seniors
Knowledge-focused CompletedThis study looked at a questionnaire called the Balance and Daily Life (EVQ) to see how well it measures balance and fall risk in frail older adults. Researchers tested 140 people aged 65 and older who could walk with or without help. The goal was to check if the questionnaire gi…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC
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Global survey reveals antibiotic dosing practices in ICUs
Knowledge-focused CompletedThis study collected information from 964 critically ill patients in intensive care units across multiple countries to understand how doctors prescribe and monitor aminoglycoside antibiotics (tobramycin, amikacin, or gentamicin). The goal was to describe current practices and ide…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 14, 2026 12:06 UTC
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Small study probes bleeding danger in stroke patients with 'leaky' brain vessels
Knowledge-focused CompletedThis study looked at 15 stroke patients who had a condition called cerebral amyloid angiopathy (CAA), which makes blood vessels in the brain fragile and prone to bleeding. All patients received a clot-busting drug (thrombolysis) for their stroke. Researchers checked CT scans 24 h…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 14, 2026 12:06 UTC
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Could a common virus and low vitamin d trigger multiple sclerosis?
Knowledge-focused CompletedThis study looked at 110 people with early signs of multiple sclerosis (MS) on brain scans but no symptoms yet. Researchers measured their Epstein-Barr virus antibodies and vitamin D levels to see if these factors help predict who will later develop MS. The goal is to better unde…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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New blood score could predict septic shock survival
Knowledge-focused CompletedThis study tested a new scoring system that uses routine blood tests to predict whether a patient with septic shock will die within one month. Researchers followed 780 adults in intensive care units and checked how well the score worked. The goal is to help doctors identify high-…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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Blood clot marker study seeks to improve detection
Knowledge-focused CompletedThis study looked at whether two blood markers (nucleosomes and free DNA) stay stable over time in healthy people and in people who have had a blood clot. Researchers measured these markers monthly for six months in 15 healthy volunteers and 15 patients with a history of venous t…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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French ICUs under the microscope: what happens to the sickest COVID-19 patients?
Knowledge-focused CompletedThis study looked at over 1,000 adults with COVID-19 who were admitted to intensive care units (ICUs) in France. Researchers tracked their care and outcomes, such as death within 28 days and serious complications like kidney injury or blood clots. The goal was to understand how t…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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Study reveals how kidney disease and diabetes affect nerve block duration
Knowledge-focused CompletedThis study looked at 120 people having hand or wrist surgery to see if kidney failure or diabetes changes how long a nerve block lasts. Researchers measured the time it took for feeling to return after the block. The goal was to understand how these metabolic conditions affect re…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC
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Anesthesia training with smart monitors may cut surgery risks
Knowledge-focused CompletedThis study looked at whether training hospital teams to use special digital monitors during anesthesia can lower the chance of death or serious problems within 28 days after surgery. Over 1,000 adults having non-cardiac surgery took part. The goal was to see if better use of thes…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC
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New blood pressure test could help kidney patients
Knowledge-focused CompletedThis study tested a new method (SFATI) for measuring blood pressure in 90 people with severe kidney failure. The goal was to see if it works as well as the standard arm-cuff method, especially when arteries are stiff or calcified. The study is complete and aims to improve blood p…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC
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MRI study sheds light on mysterious brain iron spots in blood vessel disease
Knowledge-focused CompletedThis study used MRI scans to look for iron deposits on the surface of the cerebellum in 111 people with cerebral amyloid angiopathy (CAA), a condition that weakens blood vessels in the brain. The goal was to understand where these deposits come from and how they relate to other b…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC
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Breathing tube removal method may improve oxygen levels after surgery
Knowledge-focused CompletedThis study looked at 68 adults having limb surgery under general anesthesia. It compared two methods of removing the breathing tube: one that uses positive pressure and one that uses suction. The goal was to see which method helps patients breathe on their own longer without thei…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC
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Heart clot strokes show unique brain patterns on MRI
Knowledge-focused CompletedThis study looked at brain MRI scans of 122 stroke patients to see if those with a clot in the heart (intracardiac thrombus) had different stroke patterns than those with atrial fibrillation. Researchers compared the location, size, and number of brain injuries between the two gr…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC
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Bone scanner showdown: are new devices as accurate as the old?
Knowledge-focused CompletedThis study checked if a new bone scanner (Stratos DR) gives the same body fat and muscle readings as a standard one (Discovery A). Fifty adults who needed a bone density scan had their body composition measured on both machines. The goal was to see if the new scanner is reliable …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC
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Healthy volunteers help scientists decode movement complexity
Knowledge-focused CompletedThis study looked at how healthy adults perform simple tapping tasks to understand the complexity of their movement control. Researchers used special math tools (fractal analysis) to measure patterns in performance. The goal was to explore whether these measurements could be usef…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC
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Antibiotic levels tracked in lung fluid of ventilated pneumonia patients
Knowledge-focused CompletedThis study looked at how the antibiotic ceftobiprole spreads in the blood and lungs of 12 adults with severe pneumonia who needed a breathing machine. Researchers gave a high dose continuously for 24 hours and took blood and lung fluid samples to measure drug levels. The goal was…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC
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French hospitals study gunshot wounds in ICUs
Knowledge-focused CompletedThis study reviewed the medical records of 120 people treated in French hospital ICUs for gunshot wounds between 2015 and 2021. The goal was to learn more about the types of injuries, death rates, and factors that affect survival. No new treatments were tested; instead, researche…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 14, 2026 12:03 UTC
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Twin birth study: vaginal vs. C-Section impact on incontinence
Knowledge-focused CompletedThis study looked at whether having twins vaginally or by C-section changes the risk of urine leakage 3 months after birth. It included over 3,000 first-time mothers who delivered twins after 34 weeks. Researchers used questionnaires to track bladder and pelvic floor health, aimi…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 14, 2026 12:03 UTC
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Blood thinner dilemma: study probes deadly delays in hip fracture surgery for seniors
Knowledge-focused CompletedThis study looked back at 610 elderly patients on blood thinners (DOACs) who needed hip fracture surgery. Doctors often delay surgery to let the drug wear off, which can increase the risk of death. The goal was to understand current practices and outcomes to help design a future …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 14, 2026 12:02 UTC
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Scientists hunt down colon Cancer's toughest cells
Knowledge-focused CompletedThis study examined colon cancer cells from 60 patients to find out why some cells are better at spreading and resisting chemotherapy. Researchers collected samples from tumors, blood, and metastases to study these 'cancer stem cells.' The goal was to learn more about how colon c…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 13, 2026 16:03 UTC
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Mind over matter: picturing success boosts IV skills in med students
Knowledge-focused CompletedThis study looked at whether a mental imagery session—where students vividly picture the steps in their mind—can improve their ability to insert a peripheral IV catheter on a practice mannequin. 96 fifth-year medical students took part. The goal was to see if this simple mental t…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 13, 2026 16:02 UTC
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Ultrasound may make blood draws easier
Knowledge-focused CompletedThis study tested whether using ultrasound guidance improves the process of drawing blood from the radial artery in the wrist. 74 adults who needed an arterial blood sample took part. Researchers measured how many puncture attempts were needed, pain levels, and satisfaction for b…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 13, 2026 16:02 UTC
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France's ICU expansion during COVID: a look behind the scenes
Knowledge-focused CompletedThis study examined how hospitals in France increased the number of ICU beds and staff during the COVID-19 pandemic. Researchers collected data from nearly 10,000 hospitals to understand where the extra beds came from and how medical and non-medical workers were reassigned. The g…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 13, 2026 16:02 UTC
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Scientists uncover immune clues in pregnancy complication
Knowledge-focused CompletedThis study looked at stored blood samples from 26 pregnant women to understand how immune cells (neutrophils) form web-like traps (NETs) in normal pregnancy versus preeclampsia, a serious condition. Researchers compared two ways these traps form—one that kills the cell and one th…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 13, 2026 16:02 UTC
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Robotic surgery shows promise for early throat cancer
Knowledge-focused CompletedThis study examined how often robot-assisted surgery can completely remove early-stage laryngeal (voice box) cancer with healthy tissue around it. Researchers followed 54 people with T1-T2 tumors who had this surgery. The main goal was to see if the surgical edges were cancer-fre…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 13, 2026 16:02 UTC
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New study reveals key factors behind antibiotic success in ICU patients
Knowledge-focused CompletedThis study looked at 156 critically ill patients to find out why some reach target antibiotic levels and others don't. Researchers checked blood levels of beta-lactam antibiotics and analyzed patient details. The goal is to help doctors adjust doses more accurately for better inf…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 13, 2026 16:02 UTC
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Study reveals Post-Birth diabetes risk in moms with gestational diabetes
Knowledge-focused CompletedThis study looked at 500 women who had gestational diabetes during pregnancy to see how many developed diabetes or pre-diabetes within 4 to 12 weeks after giving birth. Researchers compared women diagnosed with gestational diabetes before 24 weeks of pregnancy to those diagnosed …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 13, 2026 16:02 UTC
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Scientists compare three methods to measure pelvic extension in healthy volunteers
Knowledge-focused CompletedThis study looked at 120 healthy volunteers to see how well three different methods (clinical observation, photography, and a special imaging system called EOS) measure pelvic extension. The goal was to describe the range of pelvic movement for four common body types. The study d…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 13, 2026 16:02 UTC
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Nursing home staff under siege: PTSD rates soar during pandemic
Knowledge-focused CompletedThis study looked at how the COVID-19 pandemic affected the mental health of nursing home staff in Occitanie, France. Over 500 workers answered surveys about post-traumatic stress, depression, and burnout. The goal was to understand how common these problems were during the healt…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 13, 2026 16:01 UTC
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Stockings under the microscope: new data on vein pressure
Knowledge-focused CompletedThis study looked at how compression stockings of different strengths change the size and pressure of veins in the leg. Researchers measured these effects in 111 people, including those with chronic venous insufficiency and healthy volunteers, while they were lying down, sitting,…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 13, 2026 15:59 UTC
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Can a tablet replace the hospital visit? new device lets surgery patients monitor health from home
Knowledge-focused CompletedThis study tested a medical device called SMART ANGEL that lets patients record their blood pressure, heart rate, and oxygen levels at home after outpatient surgery. 30 adults used the device to send data to their doctors. The goal was to see if the device is easy to use and accu…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 13, 2026 15:58 UTC
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Can a video call replace your Pre-Surgery anesthesia visit?
Knowledge-focused CompletedThis study looked at whether a video call (telemedicine) is as good as an in-person visit for checking a patient's health before surgery. 172 adults scheduled for surgery at a French hospital took part. Researchers compared how well each method assessed surgical risk, reviewed me…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 13, 2026 15:58 UTC
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Tiny study probes how plasma filters affect immune cells in rare nerve disease
Knowledge-focused CompletedThis study looked at two different blood-filtering techniques (single plasma exchange and double filtration plasmapheresis) in 8 people with a rare nerve disorder called CIDP. The goal was to see how each method changes certain immune cells in the blood. The study did not test wh…
Phase: EARLY_PHASE1 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 12, 2026 13:43 UTC
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Tiny brain strokes linked to heart hole in young people
Knowledge-focused CompletedThis study looked at 50 young adults (under 60) who had a stroke with no clear cause. Researchers compared those with a small hole in the heart (PFO) to those without. They checked brain scans to see if small strokes in the back part of the brain were more common in the PFO group…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 12, 2026 13:43 UTC
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New sexuality surveys tested for women with bladder or pelvic issues
Knowledge-focused CompletedThis study tested two French-language questionnaires about sexuality in 298 women who had surgery for pelvic organ prolapse, urinary incontinence, or fecal incontinence. The goal was to see if these new tools accurately measure sexual function compared to an existing questionnair…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 12, 2026 13:42 UTC
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Scientists track bacteria shifts after Women's surgery
Knowledge-focused CompletedThis study looked at how the bacteria in the vagina, urine, and gut change before and after vaginal surgery in 60 menopausal women. Researchers took swabs before surgery and at 6 weeks and 12 months after to see if different bacteria types are linked to symptoms. The goal was to …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 12, 2026 13:42 UTC
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Do higher antibiotic doses work better for sepsis in the ICU?
Knowledge-focused CompletedThis study looked at whether giving higher doses of two common antibiotics (amikacin and gentamicin) to ICU patients with severe sepsis helps achieve the right levels in the blood. 63 patients took part. The goal was to see if the higher doses reached target concentrations, not t…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 12, 2026 13:41 UTC
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Healthy volunteers help Fine-Tune lung ultrasound for future ICU care
Knowledge-focused CompletedThis study measured normal lung ultrasound values in 30 healthy volunteers aged 18 to 50. Researchers used a technique called speckle tracking to see how the lung surface moves during breathing, both naturally and with a breathing mask. The goal was to establish a baseline for he…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 12, 2026 13:41 UTC
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Can 8 weeks of tailored exercise boost heart health in obesity and diabetes?
Knowledge-focused CompletedThis study looked at how a personalized 8-week exercise program affects heart and blood vessel function in men with obesity or type 2 diabetes. Researchers compared these groups to healthy volunteers to understand the differences. The goal was to learn more about the benefits of …
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 12, 2026 13:41 UTC
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New study hopes to predict dangerous pregnancy complication with simple blood test
Knowledge-focused CompletedThis study looked at 513 pregnant women with antiphospholipid antibody syndrome (oAPS) to see if measuring a protein called ADAMTS13 early in pregnancy could help predict preeclampsia, a serious condition involving high blood pressure. Researchers measured ADAMTS13 levels in stor…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 12, 2026 13:40 UTC
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Back pain study reveals hidden movement instability
Knowledge-focused CompletedThis study compared movement stability between 70 people with chronic low back pain and healthy volunteers matched by age, sex, and body size. Researchers measured how steady participants' movements were during bending and twisting tasks. The goal was to understand how long-term …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 12, 2026 13:39 UTC
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New tests could spot dangerous fungus earlier in ICU patients
Knowledge-focused CompletedThis study looked at 422 ICU patients to see if a combination of tests could detect Candida (a fungus) infections earlier and more accurately. The tests included blood antibody and antigen tests, DNA detection, and checking samples from multiple body sites. The goal was to improv…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 12, 2026 13:39 UTC