Antibiotic levels measured in lungs of sickest pneumonia patients
NCT ID NCT04171674
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how the antibiotic ceftobiprole moves through the blood and lungs of 12 adults with severe pneumonia who were on breathing machines. Researchers gave a high dose continuously through a vein and took blood and lung fluid samples to measure drug levels. The goal was to find the best dose to fight the infection effectively.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ceftobiprole (a high-dose antibiotic given continuously through a vein)
What this could lead to
If successful, this could help doctors determine the right dose of ceftobiprole for critically ill pneumonia patients on ventilators.
What could go wrong
This is a very small, early-stage study (12 people) focused on drug levels, not on proving the drug works or is safe. Results may not apply to all patients.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for PNEUMONIA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
CHU de Nîmes
Nîmes, Gard, 30029, France
-
Centre Hospitalier Lyon Sud,
Pierre-Bénite, Auvergne-Rhône-Alpes, 69310, France