Centre Hospitalier Universitaire De Nīmes

This study is testing a new medical device called Anchorsure® to treat a type of pelvic organ prolapse (when organs slip down into the vagina). The device is meant to make surgery faster and less painful. Researchers will follow 120 women for 3 years to see how well it works and …

This study tests a 10-week therapy program called SINTYA for young adults aged 16-25 with borderline personality disorder (BPD). The program combines group and individual sessions to help reduce impulsive behaviors and improve emotional control. Researchers will compare impulsivi…

This study compares music therapy using Music Care tablets to a gas mixture (EMONO) for reducing anxiety in 128 people with low back pain undergoing a CT-guided spinal injection. Participants will be randomly assigned to listen to music or inhale the gas during the procedure. The…

This study looks at whether a dedicated geriatric peri-operative care team can help adults aged 70 and older recover daily function better than standard care after colorectal cancer surgery. About 90 participants will be randomly assigned to either the specialized team or usual c…

This study tests whether music therapy delivered through a BeatMove device can help people with blocked leg arteries walk longer distances. About 54 participants will do a 3-month walking program, with some using the music device and others a sham version. The goal is to see if m…

This study compares two ways of doing robotic knee replacement: keeping the posterior cruciate ligament (PCL) versus removing it. Researchers want to see which approach helps patients feel less aware of their artificial joint 12 months after surgery. About 300 adults scheduled fo…

This study tests a new device called PEASY that collects urine from men who have trouble controlling their bladder. It is designed to be more comfortable than current options by using a non-adhesive strap that holds it in place without glue. The study will enroll 20 uncircumcised…

This study is testing whether a 12-week therapy program called ECCCLORE is practical and acceptable for people who have both post-traumatic stress disorder (PTSD) and addiction. The program combines skills for managing emotions, stress, and relationships. Researchers will enroll …

This study tests a new step before rectal cancer surgery: temporarily blocking the inferior mesenteric artery with a tiny coil. The goal is to see if this 'preconditioning' is safe and might reduce serious complications like leaks (fistulas) after surgery. About 30 adults with re…

This study looks at whether gut bacteria and bacterial leakage into the blood and spinal fluid play a role in type 1 narcolepsy, a rare sleep disorder. Researchers will compare 120 people with and without narcolepsy to understand how gut health might trigger the immune system to …

This study looks at whether working odd hours or having idle time at work makes people more likely to gamble in risky ways. Researchers will interview 25 adults who currently have or have had a gambling problem and who have worked in the past year. The goal is to understand how w…

This study looks at MRI scans from 120 women with advanced cervical cancer to create a model that predicts how well they will respond to standard chemoradiotherapy. The goal is to identify women who might not benefit from standard treatment early, so they can consider other optio…

This study is creating and testing a French version of a questionnaire that measures how well people with rheumatoid arthritis stick to their medication. Researchers will enroll 150 adults who have been on a stable dose of methotrexate for at least a month. The goal is to make su…

This study looks at how sleep inertia—the grogginess you feel right after waking up—affects attention in people with major depression. Researchers will compare three groups: depressed patients with sleep inertia, depressed patients without it, and healthy controls. They will use …

This study compares monthly blood tests for a nerve damage marker (pNfL) against standard yearly MRI scans in people with relapsing-remitting multiple sclerosis (RRMS). The goal is to see if the blood test can catch hidden disease activity sooner, allowing doctors to adjust treat…

This study looks at how cells in the placenta die or recycle themselves in pregnant women with conditions like preeclampsia or poor fetal growth. Researchers will compare these cell processes in 50 women to better understand why these complications happen. The goal is to find new…

This study examines the gut bacteria of children aged 1 to 3 who take long-term antibiotics for a kidney condition called vesicoureteral reflux. Researchers will compare their gut bacteria to those of children with the same condition not on antibiotics and to healthy children. Th…

This study aims to find out which factors—like physical, psychological, or social—predict whether a person with chronic low back pain will benefit from a multidisciplinary rehab program. Researchers will follow 333 adults with pain lasting at least three months, tracking their pr…

This study looks at how people adjust their walking after losing part of a leg. Researchers will measure movement, balance, and muscle activity in 75 adults with a leg amputation while they walk on different surfaces. The goal is to better understand these changes to improve futu…

This study is testing a new lab method called SPHERTEST to see if it can predict whether immunotherapy will work for people with advanced bladder cancer. Researchers will take blood and tumor samples from 32 patients to create a 3D cell model and measure how the immune system att…

This study tracks gut bacteria in 25 children (ages 6-17) with juvenile spondyloarthritis, a type of arthritis. Researchers want to see how different treatments—like anti-inflammatories, methotrexate, or biotherapy—affect the types and diversity of bacteria in the gut. They also …