Could a tiny dose of IL-2 slow ALS? new trial results are in
NCT ID NCT03039673
First seen Nov 17, 2025 · Last updated May 14, 2026 · Updated 25 times
Summary
This phase II trial tested whether low-dose interleukin-2 (IL-2) can safely slow the progression of ALS, a severe nerve disease. Over 300 newly diagnosed patients received either the drug or a placebo for 18 months. The goal was to see if boosting certain immune cells could reduce nerve inflammation and extend survival.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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APHM - Hôpital de la Timone
Marseille, 13385, France
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APHP - Groupe Hospitalier Pitié-Salpetrière
Paris, 75651, France
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CENTRE HOSPITALIER DE SAINT BRIEUC - Hôpital Yves Le Foll
Saint-Brieuc, 22027, France
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CHRU de Lille - Hôpital Roger Salengro
Lille, 59037, France
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CHRU de Montpellier - Hôpital Gui de Chauliac
Montpellier, 34295, France
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CHRU de Tours - Hôpital Bretonneau
Tours, 37044, France
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CHU de Limoges - Hôpital Dupuytren
Limoges, 87042, France
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CHU de Nice - Hôpital Pasteur
Nice, 06002, France
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CHU de Strasbourg - Hôpital de Hautepierre
Strasbourg, 67098, France
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Centre for Neuromuscular Diseases - National Hospital of Neurology
London, WC1N 3BG, United Kingdom
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HCL - Hôpital Neurologique P. Wertheimer
Lyon, 69677, France
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Institute of Neurological Sciences, Queen Elizabeth University Hospital
Glasgow, G514TF, United Kingdom
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King's MND Care and Research Centre
London, SE5 8AF, United Kingdom
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North-East London and Essex MND Regional Care Centre
London, E1 4NS, United Kingdom
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Salford Royal NHS Foundation Trust, Neurology Dept
Manchester, M6 8HD, United Kingdom
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Sheffield Care and Research Centre
Sheffield, S10 2JF, United Kingdom
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Trafford Centre for Biomedical Research
Brighton, BN1 9RY, United Kingdom
Conditions
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