Global survey reveals how ICUs use powerful antibiotics

NCT ID NCT02850029

Completed Knowledge-focused Sponsor: Centre Hospitalier Universitaire de Nīmes Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study surveyed 964 intensive care patients across multiple countries to understand how doctors currently prescribe and monitor aminoglycoside antibiotics (tobramycin, amikacin, gentamicin). Researchers collected data on dosing, therapy duration, and drug monitoring during the first week of treatment. The goal was to describe real-world practices, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this survey could help identify gaps and improve how aminoglycoside antibiotics are dosed and monitored in critically ill patients.
What could go wrong: This is an observational study, not a treatment trial. It only describes current practices and does not test any new intervention or directly improve patient outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Critical Illness

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CRITICAL ILLNESS UNDERDOSING OF AMINOGLYCOSIDES

Contacts and locations

Locations

AP-HM - Hopital Nord

Marseille, 13915, France
AP-HP - Bicetre

Paris, 94275, France
AP-HP - Hopital Paris St Antoine

Paris, 75012, France
AP-HP - Paris St Louis

Paris, 75010, France
APHM La timone

Marseille, PACA, 13000, France
APHP- Bichat

Paris, 75018, France
APHP- Descartes

Paris, 75908, France
APHP-Hopital Georges Pompidou

Paris, 75908, France
Aphm- La Conception

Marseille, 13385, France
Aphp - Pitie Salpetriere

Paris, 75013, France
Aphp- Pitie Salpetriere

Paris, 75013, France
Athens Hippocratio Hospital

Athens, Greece
CHI Robert Ballanger

Aulnay-sous-Bois, 93602, France
CHU CAEN

Caen, 14033, France
CHU La Reunion-Hopital Felix Guyon

Saint-Denis, 97400, France
CHU MONTPELLIER-Hopital Lapeyronnie

Montpellier, 34295, France
CHU MONTPELLIER-Hopital St Eloi

Montpellier, 34295, France
CHU NANTES- hôpital Nord Laennec

Nantes, 44093, France
CHU Nice- Hopital Pasteur

Nice, 06001, France
CHU Nice-Hopital L'Archet

Nice, 06202, France
CHU REIMS- Hopital Robert Debré

Reims, 51100, France
CHU RENNES - Hopital Pontchaillou

Rennes, 35033, France
CHU ROUEN- Hopital Nicolle

Rouen, 76031, France
CHU SAINT-ETIENNE - Hopital Nord

Saint-Etienne, 42270, France
CHU TOULOUSE- Hopital Rangueil

Toulouse, 31059, France
Centre Hospitalier Aix-En-Provence

Aix-en-Provence, 13097, France
Centre Hospitalier Arles

Arles, 13637, France
Centre Hospitalier Aurillac

Aurillac, 15000, France
Centre Hospitalier Avignon

Avignon, 84902, France
Centre Hospitalier Bourg En Bresse

Bourg-en-Bresse, 01012, France
Centre Hospitalier Charleville-Mezieres

Charleville-Mézières, 08011, France
Centre Hospitalier D'Ales

Alès, 30100, France
Centre Hospitalier La Rochelle-Hopital Saint Louis

La Rochelle, 17019, France
Centre Hospitalier Sainte Catherine

Saint-Brieuc, 22027, France
Centre Hospitalier Sainte Catherine

Saverne, 67703, France
Centre Hospitalier Sambre-Avesnois

Maubeuge, 59600, France
Centre Hospitalier Valence

Valence, 26953, France
Centre Hospitalier de BOULOGNE SUR MER

Boulogne-sur-Mer, 62321, France
Centre Hospitalier de Compiegne

Compiègne, 60200, France
Centre Hospitalier de MORLAIX

Morlaix, 29672, France
Centre Hospitalier de Montauban

Montauban, 82013, France
Centre Hospitalier de PAU

Pau, 64046, France
Centre Hospitalier de Roanne

Roanne, 42328, France
Centre Hospitalier de Rodez

Rodez, 12027, France
Centre Hospitalier de Salon de Provence

Salon-de-Provence, 13658, France
Centre Hospitalier de Toulon, Hopital Sainte Musse

Toulon, 83056, France
Centre Hospitalier de Valenciennes

Valenciennes, 59322, France
Centre Hospitalier du Mans

Le Mans, 72037, France
Centre Universitaire de Nimes

Nîmes, 30029, France
Chru Besancon

Besançon, 25030, France
Chru Brest

Brest, 29609, France
Chru Nancy -Hopital de Brabois

Nancy, 54511, France
Chu Amiens

Amiens, 80054, France
Chu Angers

Angers, 49100, France
Chu Angers

Angers, 49933, France
Chu Bordeaux

Bordeaux, 33076, France
Chu Brest- Hopital Cavale

Brest, 29609, France
Chu Clermont-Ferrand

Clermont-Ferrand, 63000, France
Chu Grenoble

Grenoble, 38043, France
Chu Lyon- Hopital La Croix Rousse

Lyon, 69317, France
Chu Lyon- Lyon Sud

Lyon, 69495, France
Chu Nantes- Hopital Hotel Dieu

Nantes, 44035, France
Chu Poitiers

Poitiers, 86021, France
Frankston Hospital Victoria

Frankston, Australia
G. Gennimatas General Hospital

Thessaloniki, Greece
Guy'S and St Thomas'

London, United Kingdom
Hospital Barros Luco Trudeau

Santiago, Chile
Hospital Base de Valvidia

Valdivia, Los Ríos Region, Chile
Hospital CU Chile

Santiago, Chile
Naval and Veterans Hospital of Athens

Athens, Greece
Oxford Radcliffe Hospitals

Oxford, United Kingdom
Royal Brisbane Women's Hospital

Brisbane, Queensland, 4029, Australia
Royal Brisbane and Women's Hospital

Brisbane, Australia
Salford royal

Manchester, United Kingdom
Salvador Santiago Hospital

Santiago, Chile
Sandwell and west Birmingham hospital

Birmingham, United Kingdom
Sheffield Teaching Hospitals

Sheffield, United Kingdom
Southampton University Hospitals

Southampton, United Kingdom
St Helens and Knowsley Hospitals

Prescot, United Kingdom
Sunshine Coast hospital

Sunshine Coast, Australia
Toowoomba Hospital

Toowoomba, Australia
University Critical Care Department Aghioi Anargyroi Hospital

Athens, Greece
University Hospital Birmingham

Birmingham, United Kingdom
University Hospital of South Manchester

Manchester, United Kingdom
University Hospital of loannina

Ioannina, Greece

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