HIV

This study looked at how well the Prevnar 13 (PCV13) vaccine works to prevent pneumonia in adults living with HIV. Researchers analyzed existing health records of over 350,000 people to compare rates of pneumonia between those who received the vaccine and those who did not. The g…

This study tested a new program in HIV clinics to better identify and treat substance use, depression, and anxiety. Over 10,000 HIV-positive adults used tablets to screen for these issues during routine visits. Those who screened positive could then receive counseling from a beha…

This early-stage study tested the safety of a new HIV drug called LP-98, given as injections under the skin. It involved 40 people with HIV who had not yet started treatment. Researchers checked for side effects and measured how the drug moved through the body at different doses.

This study aimed to find safe and effective doses of the drug bedaquiline for children and adolescents with a hard-to-treat form of tuberculosis (TB) that resists standard antibiotics. It involved 54 young people, from infants to teens, some also living with HIV. Researchers care…

This study tested a new way to deliver HIV care to pregnant and new mothers in Kenya. The goal was to make care simpler and more efficient for women who are doing well on treatment, so doctors could focus more time on those who need extra help. Researchers wanted to see if this a…

This study looked back at the health records of 800 people with HIV to compare two different treatment plans. It aimed to see if a two-drug regimen works as well as a standard three-drug regimen at keeping the virus under control for 48 weeks. The research focused on people in th…

This study tested if a reward program could work in a regular doctor's office to help people with two connected problems: stimulant use and HIV. It offered small incentives to 37 participants for providing weekly urine tests that showed they were not using stimulants and were tak…

This study followed HIV-positive patients who received organ transplants from HIV-positive deceased donors. Researchers wanted to see if this practice was safe and effective compared to receiving organs from HIV-negative donors. They tracked patient survival, organ function, and …

This study tested a community support program for adolescent girls and young women in Zambia to improve HIV prevention and care. It combined education for girls and their families, youth clubs for peer support, and special wellness clinics offering health services. Researchers me…

This study tested a newer HIV medication called dolutegravir in pregnant women who were diagnosed late in pregnancy. The goal was to see if the drug was safe for both mother and baby, how it moved through their bodies, and if it could quickly lower the mother's virus levels to he…

This study tested whether training healthcare workers could improve HIV care in Mozambique. Researchers gave staff at four clinics training to reduce burnout and stigma, which often cause patients to abandon treatment. They measured if this training helped workers feel better abo…

This study tested a new approach to help people who inject drugs and have HIV. It trained people who were already successfully on addiction medication to become peer educators for their friends and social contacts. The goal was to see if this peer support could encourage more peo…

This study tested a program called 'Family Connections' for teenagers and young adults (ages 15-21) living with HIV in Zambia and their caregivers. The goal was to see if group sessions providing family support and reducing self-stigma could help young people stick to their medic…

This study tested a new support program designed to help people with HIV, hepatitis C, or substance use disorders get medical care after they are released from prison. Researchers worked with 219 men and women before their release to see if the program was practical and acceptabl…

This study tested a new support program for people living with HIV who also use drugs like opioids or stimulants. The program combined a phone app for medication reminders with therapy sessions focused on managing emotions and communication. Researchers wanted to see if this appr…

This study tested a new clinic program designed to improve high blood pressure care for adults living with HIV in South Africa. The program trained healthcare workers and used new systems to better screen for and manage high blood pressure during regular HIV clinic visits. Resear…

This study tested if a weekly injection called PRO 140 could control HIV by itself for 48 weeks, instead of the standard daily pill combinations. It involved 562 adults whose HIV was already well-controlled on daily medications. The goal was to see if switching to just the weekly…

This study tested a support program designed for transgender women living with HIV in the Dominican Republic. The program, called 'Gender-affirming Abriendo Puertas,' offered individual counseling, peer support, and community activities to help participants stay on their medicati…

This study tested if adjusting the dose of two common HIV drugs (efavirenz or atazanavir) based on a patient's genetics and drug levels in their blood could work as well as standard fixed doses, but with fewer side effects and better cost-effectiveness. It involved 190 adults in …

This study tested a group therapy program designed to help men who have sex with men in South Africa. The goal was to see if improving mental health could also help them take their HIV prevention or treatment medications more consistently. The program adapted an existing, proven …

This study tested different ways to help people with HIV in South Africa stay on their medication and achieve viral suppression. Researchers tried flexible options like offering incentives, community-based care, and home delivery of medication for people who were struggling with …

This study tested whether HIV patients with well-controlled virus could safely switch from three-drug to two-drug therapy. Researchers wanted to see if this simpler treatment could maintain viral suppression while reducing medication side effects and costs. The trial involved 224…

This study tested a new community health worker program designed to help people living with HIV better manage their high blood pressure in Tanzania. The program involved training local health workers to provide counseling, monitor blood pressure, and help patients get medication …

This study tested if adding the drug efavirenz to standard HIV treatment is safe and can reduce the hidden, dormant virus that persists even with effective therapy. Seven adults with well-controlled HIV took efavirenz alongside their usual medications for about six months. Resear…

This study tested a new, long-acting injectable drug called Lipovirtide for people newly diagnosed with HIV who had not yet started treatment. The goal was to see if giving this injection once a week or once every two weeks, along with daily pills, could effectively control the v…

This study tested a community program in Kenya designed to help people living with HIV. It combined a savings and loan group with education on parenting, business skills, and mental health therapy. The goal was to see if this support system could help people stick to their HIV me…

This study tested whether using an augmented reality (AR) app on a smartphone could help men who have sex with men (MSM) perform HIV self-tests more easily and confidently. Researchers compared the AR app to standard paper instructions. They measured how confident users felt, how…

This study tested two new screening tools to help doctors quickly rule out tuberculosis (TB) in adults with symptoms like cough or fever. Researchers enrolled 1,400 adults in South Africa and Lesotho to see how accurately a chest X-ray analysis software and a simple blood protein…

This study aimed to find people with undiagnosed HIV who were already in the hospital. Researchers tested 300 patients at a hospital in Milan who showed certain health conditions or reported risky behaviors. The goal was to see how common hidden HIV infections are in this setting…

This study tested a new, faster HIV test for babies and young children in Zambia. The goal was to see if getting test results right away, at the community clinic, would help more HIV-positive infants start life-saving antiretroviral therapy (ART) sooner. Researchers also wanted t…

This study tested a web-based program designed to help Black women at risk for HIV and sexually transmitted infections (STIs) in Texas. The program guided them through using at-home test kits, mailing them in, checking results, and connecting to treatment or preventive medication…

This study tested a combination HIV prevention strategy for men in Kisumu, Kenya, who are at risk of getting HIV. It offered participants a daily preventive pill (PrEP) along with extra support like self-testing kits and text message reminders to help them take the pill consisten…

This study tested whether a mobile app could help men at high risk for HIV in China test themselves more regularly and connect to care if needed. About 1,800 HIV-negative men were randomly assigned to either use the special app or receive standard information. Researchers checked…

This study tested the safety and how the body processes a new monthly oral pill, MK-8527, intended to help prevent HIV infection. It involved 352 adults at low risk for HIV who took either the pill or a placebo for comparison. The main goal was to see how well the pill was tolera…

This study tested a new program designed to increase cervical cancer screening for women living with HIV in Kenya. The program trained community health workers to provide education and support in a way that reduces the shame and fear often associated with HPV, HIV, and cancer. Re…

This study tested two different HIV prevention programs adapted for African-born women living in the US. It compared a brief, one-on-one skills session with a more in-depth, peer-led group program. The goal was to see which approach was more effective at increasing condom use and…

This study adapted and tested a community-based program to prevent HIV among people who inject drugs in the high-violence US-Mexico border region. The program involved three main parts: social network-based HIV testing, peer-led educational sessions, and community-wide health eve…

This study tested an online mindfulness program designed to help young gay, bisexual, and queer men cope with stress related to their identity. The goal was to see if reducing this stress could improve mental health and lower behaviors that increase HIV risk. Researchers enrolled…

This study tested different payment models for getting HIV prevention medications (PrEP and PEP) at private pharmacies in Kenya. Researchers wanted to see whether having clients pay a small fee, having the program cover the cost, or adding counseling support would help more peopl…

This study tested a digital health program designed to help male couples in the U.S. work together to prevent HIV and sexually transmitted infections (STIs). Over 16 months, 778 men in relationships used an online toolkit to create and follow personalized prevention plans and agr…

This study aimed to find the safest and most effective daily pill dose to prevent HIV in pregnant women in Africa. Researchers tested three different strengths of the prevention medication in 54 pregnant women to see how their bodies processed the drug and to check for safety. Th…

This study tested whether offering small financial rewards could encourage more HIV testing among women at high risk. Researchers worked with community organizations to train staff and randomly assigned 334 women to either receive standard testing referrals or those same referral…

This large, international study aimed to see if a daily cholesterol-lowering pill (pitavastatin) could prevent heart attacks, strokes, and other major heart-related problems in adults living with HIV. Over 7,700 participants on stable HIV treatment, who had a low-to-moderate risk…

This study tested a prevention program designed specifically for women who use drugs like cocaine, heroin, or methamphetamine. Researchers wanted to see if peer-led education sessions and health check-ups could help these women reduce risky drug and sexual behaviors that lead to …

This study tested whether a special training and support program for community center staff could help them run a proven teen pregnancy and HIV prevention class more effectively. It involved 909 youth aged 10-14 across 32 Boys & Girls Clubs. The goal was to see if better-trained …

This study tested a 3-drug combination pill called Delstrigo as an emergency prevention treatment for people who may have been recently exposed to HIV. 399 adults who went to the emergency room after possible HIV exposure took the pill daily for 28 days. Researchers tracked how m…

This study tested a new way of talking to people in Uganda to encourage them to get tested for HIV. The messages focused on reassuring couples that they could still have stable relationships and healthy families, even with HIV, thanks to modern prevention and treatment options. R…

This study tested whether a WhatsApp-based program could encourage more men who have sex with men in India to get tested for HIV and connect to preventive care like counseling or PrEP medication. Researchers compared the WhatsApp program to simpler approaches like just offering f…

This study tested whether providing HIV prevention medication (PrEP) immediately at a needle exchange program helps people stay HIV-negative. Researchers enrolled 90 adults who use the syringe service and tested negative for HIV. They measured if getting the medicine right at the…

This study tested a program to prevent new HIV infections among young couples in Cape Town, South Africa, who use alcohol or drugs. It involved 962 people across 24 communities. The program combined a two-day workshop for couples with community education to reduce stigma, aiming …

This study tested a new counseling program called STARS, designed specifically for transgender women who have experienced intimate partner violence. The program aimed to help them reduce their risk of HIV and improve their safety in relationships. Researchers compared STARS to a …

This study tested a new way to help young men in Vietnam check for HIV. Researchers wanted to see if providing at-home test kits with online video guidance from a counselor would make people more likely to get tested regularly. They compared this online method to the usual way of…

This study created and tested a short play (an 'ethnodrama') designed to reduce community stigma against young women in Kenya who use PrEP, a daily pill to prevent HIV. Researchers gathered feedback from 63 people, including young women, their partners, family, and community lead…

This study tested whether a special counseling program for couples could improve their relationship and overall well-being. It involved 88 male couples in China where one partner has HIV and the other does not. Half the couples received three counseling sessions together, while t…

This study tested a new online mindfulness program designed to help young gay and bisexual men cope with stress related to their identity. The goal was to see if the program was practical and acceptable to participants, and if it could improve their mental health and reduce behav…

This small, completed pilot study tested whether a non-invasive brain stimulation technique called TMS could help people living with HIV quit smoking. Researchers compared four sessions of real TMS to fake (sham) stimulation to see if it reduced participants' cravings and their a…

This study explored how Buddhist teachings could help reduce the social stigma experienced by people living with HIV in Myanmar. Researchers worked with 19 participants to adapt an existing program aimed at lowering stigma and improving quality of life. The goal was to see if cul…

This study tested a new online therapy program designed to support transgender and gender-diverse people in Romania. The program aimed to reduce depression, anxiety, and behaviors linked to HIV risk through 16 weekly video sessions with a trained therapist. Researchers worked wit…

This study developed and tested a digital app to help pregnant, unmarried teenagers living with HIV in Kenya. The app aimed to help them cope with the stigma of HIV and pregnancy, improve their confidence in talking to family, and get better support. Researchers tested the app wi…

This study tested whether a 12-week group therapy program was practical and helpful for older adults living with HIV. Fifty participants were randomly assigned to either join the therapy groups or receive basic health information. The goal was to see if learning stress management…

This study tested two counseling programs designed to help HIV-positive mothers and their children live better. Researchers wanted to see if teaching coping skills and medication management could improve their quality of life, mood, and family relationships. The study involved 13…

This study tested a training method to help emergency department nurses better understand HIV testing and reduce stigma. About 74 nurses were split into two groups. One group received standard learning materials, while the other also went through a real, anonymous HIV test and co…

This study aimed to understand why older women who use cannabis have a higher risk of falling. Researchers compared how cannabis versus a placebo affected walking, balance, and thinking skills in 25 older women, some with HIV and some without. They tested participants under diffe…

This study aimed to gather detailed health information from over 1,300 people living with HIV in Liberia over three years. Participants attended regular clinic visits where researchers collected health data and samples. The goal was to better understand how HIV affects people in …

This study aims to understand why some HIV treatments fail by examining the virus in people whose medication is no longer working effectively. Researchers collected blood samples from over 1,100 people across 15-20 countries who were taking a common HIV drug (dolutegravir) but st…

This study aimed to understand how well the Pfizer COVID-19 vaccine works in adults with weakened immune systems compared to healthy adults. Researchers measured antibody levels in the blood and nose of 196 participants, including people with conditions like cancer, HIV, and orga…

This study tested a special training program for doctors and nurses who help women give birth in Tanzania. The goal was to see if the training could reduce stigma against women with HIV and make childbirth care more respectful. Researchers compared the experiences of over 200 wom…

This study aimed to understand how starting HIV medication affects body fat and heart health risks. Researchers followed 56 people with HIV who were about to begin treatment, measuring their body composition and heart health markers over time. The goal was to learn about connecti…

This study aimed to understand how insomnia affects pain sensitivity, physical function, and inflammation in people living with HIV. Researchers followed 171 participants—some with HIV, some without, and some with insomnia—measuring their sleep patterns, pain responses, and blood…

This study aimed to understand why people living with HIV are at higher risk for other health problems like heart disease and diabetes, even when their virus is controlled by medication. Researchers followed 320 Chilean patients, with and without metabolic syndrome, to collect de…

This study aimed to understand the connection between oral health and long-term health issues in people living with HIV. Researchers followed 227 adults with HIV on stable medication for about 2.5 years, checking their dental health, collecting samples, and measuring inflammation…

This study aimed to gather women's thoughts and opinions to help design better vaginal products for preventing HIV and other sexually transmitted infections. Researchers asked 36 women about applicator designs they would find easy to prepare and use. The goal was to use this feed…

This study tested whether a document called 'Voicing My CHOiCES' helps young adults with cancer or other serious illnesses plan for their future care. Researchers wanted to see if using the document reduced anxiety, improved communication with loved ones, and increased acceptance…

This study aimed to measure and understand the hidden, inactive HIV that persists in the body even when treatment is working well. Researchers followed 90 Ugandan adults with well-controlled HIV for up to 20 years, taking yearly blood samples. The goal was to see how much hidden …

This study aims to understand if a common HIV medication called dolutegravir causes excess weight gain during pregnancy and affects the long-term metabolic health of both mothers and their children. Researchers will follow about 1,900 pregnant women, some with HIV and some withou…

This study aimed to measure how common HIV and other sexually transmitted infections are among Ukrainian refugees living in Slovakia. Researchers offered free, rapid finger-prick tests for HIV, syphilis, and hepatitis to 660 adult refugees at health centers in Bratislava. The goa…

This study aimed to understand if different types of HIV medications lead to different long-term health issues, like bone, kidney, or metabolic problems, in people living with HIV. Researchers followed 215 newly diagnosed, treatment-naive adults in Hong Kong for up to 5 years aft…