Personalized HIV dosing: genetic and drug monitoring trial aims to reduce side effects
NCT ID NCT03385473
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This completed study tested whether using genetic information and measuring drug levels in the blood can help doctors choose the right dose of HIV medications (efavirenz or atazanavir) for each patient. 190 adults starting HIV treatment for the first time took part across four sites in Buenos Aires. The goal was to see if this personalized approach could reduce side effects and improve treatment success compared to standard dosing.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could show that personalized dosing based on genetics and drug levels makes HIV therapy safer and more effective.
What could go wrong
This is a small, early-stage feasibility study, not a large trial. The approach may not prove better than standard care or may be too complex for routine use.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hospital Italiano de Buenos Aires - Infectious Diseases Section
Buenos Aires, Buenos Aires F.D., 1181, Argentina