Quick urine test could spot HIV pill problems before virus rebounds

NCT ID NCT05333679

Completed Knowledge-focused Sponsor: University of California, San Francisco Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new urine-based rapid test (UTRA) that checks if people with HIV are taking their medication tenofovir as prescribed. The goal is to catch adherence problems early, before the virus level in blood rises. Researchers compared the urine test results with blood drug levels, self-reports, and pharmacy records in 200 participants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: urine tenofovir rapid assay (UTRA) test
What this could lead to: If successful, this test could help clinics identify adherence problems early and provide timely support, keeping HIV suppressed.
What could go wrong: This is a completed study with 200 participants, so results are limited in size and may not apply to all settings. The test only checks for one medication (tenofovir) and may miss other adherence issues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease Risk Reduction Behavior

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RISK REDUCTION

Contacts and locations

Locations

Desmond Tutu Health Foundation, University of Cape Town

Cape Town, Western Cape, 7925, South Africa

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