HIV drug Dolutegravir's impact on pregnancy weight under the microscope

NCT ID NCT04991402

First seen Feb 20, 2026 · Last updated Jun 17, 2026 · Updated 12 times

Summary

This study followed about 1,900 pregnant women and their babies for two years to see how HIV and the medication dolutegravir affect weight gain and overall metabolic health. Researchers compared women with HIV to those without, and also looked at differences between women who started dolutegravir during pregnancy versus those who were already taking it. The goal was to understand the links between HIV treatment, obesity, and health outcomes for both mothers and children.

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Contacts and locations

Locations

  • Gugulethu Community Health Center

    Cape Town, South Africa

  • Mitchell's Plain Community Health Center

    Cape Town, South Africa

Conditions

The condition(s) this trial relates to.

HIV infectious disease Obesity obesity disorder Pediatric Obesity Pregnancy in Obesity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.