HIV drug resistance map: brazil study reveals why some treatments fail

NCT ID NCT07618507

Completed Knowledge-focused Sponsor: Federal University of São Paulo Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 777 people with HIV in Brazil who failed their first treatment with tenofovir, lamivudine, and dolutegravir. Researchers wanted to understand what types of drug resistance and virus subtypes were involved. The goal is to improve treatment choices for people in Brazil and similar countries.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Tenofovir/Lamivudine and Dolutegravir
What this could lead to: If successful, this study could help doctors choose better HIV treatments for people in Brazil and similar countries by understanding which drug resistances are common.
What could go wrong: This is an observational study, not a test of a new treatment. It only looks at people who already failed therapy, so results may not apply to everyone with HIV.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV HIV-1-INFECTION

Contacts and locations

Locations

Centro Especializado em Doenças Infecciosas (CEDIN-DF)

Brasília, Federal District, 70351-580, Brazil
Centro Estadual Especializado em Diagnóstico, Assistência e Pesquisa (CEDAP)

Salvador, Estado de Bahia, 40100-160, Brazil
Fundação de Medicina Tropical Doutor Heitor Vieira Dourado

Manaus, Amazonas, 69040-000, Brazil
Hospital Nossa Senhora da Conceição

Porto Alegre, Rio Grande do Sul, 91350-200, Brazil
Hospital Santa Marcelina

São Paulo, São Paulo, 08270-070, Brazil
LADI - Laboratório de Apoio Diagnóstico em Infectologia (Hospital Universitário Miguel Riet Corrêa Jr)

Porto Alegre, Rio Grande do Sul, 90040-000, Brazil
Retrovirology Laboratory - UNIFESP

São Paulo, São Paulo, 04039-032, Brazil
Serviço Especializado em IST/HIV/AIDS Viamão

Viamão, Rio Grande do Sul, 94480-560, Brazil
Unidade de Infectologia William Rocha

Guarujá, São Paulo, 11471-000, Brazil

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