HIV drug resistance map: brazil study reveals why some treatments fail

NCT ID NCT07618507

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 777 people with HIV in Brazil who failed their first treatment with tenofovir, lamivudine, and dolutegravir. Researchers wanted to understand what types of drug resistance and virus subtypes were involved. The goal is to improve treatment choices for people in Brazil and similar countries.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Tenofovir/Lamivudine and Dolutegravir

What this could lead to

If successful, this study could help doctors choose better HIV treatments for people in Brazil and similar countries by understanding which drug resistances are common.

What could go wrong

This is an observational study, not a test of a new treatment. It only looks at people who already failed therapy, so results may not apply to everyone with HIV.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centro Especializado em Doenças Infecciosas (CEDIN-DF)

    Brasília, Federal District, 70351-580, Brazil

  • Centro Estadual Especializado em Diagnóstico, Assistência e Pesquisa (CEDAP)

    Salvador, Estado de Bahia, 40100-160, Brazil

  • Fundação de Medicina Tropical Doutor Heitor Vieira Dourado

    Manaus, Amazonas, 69040-000, Brazil

  • Hospital Nossa Senhora da Conceição

    Porto Alegre, Rio Grande do Sul, 91350-200, Brazil

  • Hospital Santa Marcelina

    São Paulo, São Paulo, 08270-070, Brazil

  • LADI - Laboratório de Apoio Diagnóstico em Infectologia (Hospital Universitário Miguel Riet Corrêa Jr)

    Porto Alegre, Rio Grande do Sul, 90040-000, Brazil

  • Retrovirology Laboratory - UNIFESP

    São Paulo, São Paulo, 04039-032, Brazil

  • Serviço Especializado em IST/HIV/AIDS Viamão

    Viamão, Rio Grande do Sul, 94480-560, Brazil

  • Unidade de Infectologia William Rocha

    Guarujá, São Paulo, 11471-000, Brazil