HIV patients may ditch one drug without losing viral control

NCT ID NCT02302547

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether people with HIV who have a low viral reservoir can safely switch from a three-drug regimen to a two-drug regimen (Truvada alone) while keeping the virus under control. The goal is to reduce long-term side effects and treatment costs. The trial involved 224 participants with well-controlled HIV and looked at viral load after 48 weeks.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU de NANCY

    Nancy, 54035, France

  • Centre de diagnostic et thérapeutique, Hopital Hotel Dieu

    Paris, 94010, France

  • Consultation Maladies Infectieuses, Chu de Poitiers, Cedex

    Poitiers, 86021, France

  • Hospital Tenon

    Paris, 75970, France

  • Maladies Infectieuses, CHU de ROUEN

    Rouen, 76031, France

  • Médecine Interne, Hôpital FOCH

    Suresnes, 92151, France

  • Service Universitaire des Maladies Infectieuses et du Voyageur, CH DRON

    Tourcoing, 59200, France

  • Service d'Immunologie Clinique centre de Vaccination anti- VIH ANRS Hopital Henri- Mondor

    Créteil, 94010, France

  • Service de Medecine Interne et Maladies Infectieuses, CHRU BRETONNEAU, TOURS CEDEX9

    Tours, 37044, France

  • Service de Médecine Interne et Maladies Infectieuses, Groupe Hospitalier La Rochelle, Cedex 01

    La Rochelle, 17019, France

  • Service de Médecine Interne, CH de SAINTONGE- BP 326

    Saintes, 17108, France

  • Service de Pneumologie, centre Hospitalier Fontenoy, CH de CHARTRES

    Le Coudray, 28630, France

  • Service des Maladies Infectieuses et tropicales, APHP SAINT LOUIS

    Paris, 75475, France

  • Service des Maladies Infectieuses, CHR Orléans La Source, ORLEANS CEDEX 2

    CHR d'ORLEANS, 45067, France

  • Service des maladies Infectieuses et tropicales, CH GEORGES RENON

    Niort, 79021, France

  • Unité des Maladies Infectieuses, CHU de CAEN

    Caen, 14033, France

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