Exercise may fight inflammation and disability in older HIV patients

NCT ID NCT02101060

Completed Symptom relief Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether a 16-week program of aerobic and resistance exercise could improve physical function and reduce inflammation in HIV-infected veterans aged 50 and older. Thirty-three participants completed the program, and researchers measured changes in heart and muscle health. The goal is to find safe ways to prevent disability as people age with HIV.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: exercise (aerobic and resistance training)
What this could lead to: If it works, this could point toward a safe, drug-free way to help older HIV patients stay active and reduce inflammation.
What could go wrong: This is a small, early study with only 33 participants, so results may not apply to everyone. Exercise may not be enough to significantly change inflammation or function.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease Inflammation Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV

Contacts and locations

Locations

Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD

Baltimore, Maryland, 21201, United States
Salem VA Medical Center, Salem, VA

Salem, Virginia, 24153-6404, United States

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