Immune system disorder
MONDO:0005046A disorder resulting from an abnormality in the immune system.
Also known as: disease of immune system, disease or disorder of immune system, disorder of immune system, immune disease, immune disorder, immune dysfunction, immune system disease or disorder, immune system disorder
12993 clinical trials for this condition and its sub-types, 152 tagged with Immune system disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Immune system disorder
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Autoimmune disease 315 trials · 4,049 incl. sub-types
47 sub-types
- Autoimmune disorder of the nervous system 47 trials · 1,067 incl. sub-types Sub-types →
- Autoimmune disorder of gastrointestinal tract 0 trials · 942 incl. sub-types Sub-types →
- Autoimmune disorder of endocrine system 1 trial · 929 incl. sub-types Sub-types →
- CNS demyelinating autoimmune disease 5 trials · 859 incl. sub-types Sub-types →
- Autoimmune disorder of musculoskeletal system 0 trials · 797 incl. sub-types Sub-types →
- Lupus erythematosus 40 trials · 551 incl. sub-types Sub-types →
- Scleroderma 47 trials · 305 incl. sub-types Sub-types →
- Autoimmune disorder of exocrine system 0 trials · 197 incl. sub-types Sub-types →
- Autoimmune disorder of blood 0 trials · 152 incl. sub-types Sub-types →
- Autoimmune thrombocytopenia 8 trials · 113 incl. sub-types Sub-types →
- Vitiligo 100 trials Sub-types →
- Antiphospholipid syndrome 58 trials · 59 incl. sub-types Sub-types →
- Autoimmune bullous skin disease 7 trials · 56 incl. sub-types Sub-types →
- Immunoglobulin G4-related sclerosing disease 30 trials · 34 incl. sub-types Sub-types →
- Rheumatic fever 17 trials
- Overlapping connective tissue disease 2 trials · 15 incl. sub-types Sub-types →
- Autoimmune lymphoproliferative syndrome 11 trials · 12 incl. sub-types Sub-types →
- Undifferentiated connective tissue syndrome 7 trials
- Autoimmune pulmonary alveolar proteinosis 6 trials
- Type III hypersensitivity disease 3 trials · 6 incl. sub-types Sub-types →
- Anti-glomerular basement membrane disease 5 trials
- Autoimmune disease of ear, nose and throat 0 trials · 4 incl. sub-types Sub-types →
- Autoimmune disorder of cardiovascular system 0 trials · 3 incl. sub-types Sub-types →
- Cryoglobulinemia 3 trials Sub-types →
- Susac syndrome 2 trials
- Autoimmune disease, multisystem, infantile-onset 0 trials · 2 incl. sub-types Sub-types →
- Anti-neutrophil antibody associated vasculitis 1 trial
- Phacolytic glaucoma 1 trial
- Secondary neonatal autoimmune disease 0 trials · 1 incl. sub-types Sub-types →
- Jaccoud syndrome 0 trials
- Kimura disease 0 trials
- Reynolds syndrome 0 trials
- Autoerythrocyte sensitization syndrome 0 trials
- Autoimmune disease with susceptibility to mycobacterium tuberculosis 0 trials
- Autoimmune glomerulonephritis 0 trials
- Autoimmune pulmonary disease due to PD-1 deficiency 0 trials
- Autoimmune urticaria 0 trials
- Euthyroid Graves orbitopathy 0 trials
- Multisystem autoimmune disease due to IKAROS gain of function 0 trials
- Non-specific autoimmune brainstem encephalitis with characteristic antibodies 0 trials
- Non-specific autoimmune brainstem encephalitis without characteristic antibodies 0 trials
- Non-specific autoimmune cerebellar ataxia with characteristic antibodies 0 trials
- Non-specific autoimmune cerebellar ataxia without characteristic antibodies 0 trials
- Non-specific autoimmune supratentorial encephalitis with characteristic antibodies 0 trials
- Non-specific autoimmune supratentorial encephalitis without characteristic antibodies 0 trials
- Tempi syndrome 0 trials
- Type II hypersensitivity reaction disease 0 trials
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Leukocyte disorder 6 trials · 3,581 incl. sub-types
23 sub-types
- B-cell neoplasm 305 trials · 3,174 incl. sub-types Sub-types →
- T-cell leukemia 9 trials · 137 incl. sub-types Sub-types →
- B cell deficiency 5 trials · 86 incl. sub-types Sub-types →
- Leukopenia 6 trials · 78 incl. sub-types Sub-types →
- Dendritic cell sarcoma 0 trials · 53 incl. sub-types Sub-types →
- Eosinophil disorder 2 trials · 51 incl. sub-types Sub-types →
- Langerhans cell histiocytosis 40 trials · 41 incl. sub-types Sub-types →
- Phagocyte bactericidal dysfunction 0 trials · 37 incl. sub-types Sub-types →
- Mastocytosis 15 trials · 34 incl. sub-types Sub-types →
- Functional neutrophil defect 0 trials · 13 incl. sub-types Sub-types →
- Mast cell activation syndrome 8 trials · 9 incl. sub-types Sub-types →
- POEMS syndrome 8 trials
- Subcutaneous panniculitis-like T-cell lymphoma 8 trials
- EBV-positive T-cell lymphoproliferative disorder of childhood 3 trials · 7 incl. sub-types Sub-types →
- Thymoma type B 0 trials · 4 incl. sub-types Sub-types →
- Human granulocytic anaplasmosis 1 trial
- Pelger-Huet anomaly 0 trials
- Eosinophil peroxidase deficiency 0 trials
- Hereditary neutrophilia 0 trials
- Human monocytic ehrlichiosis 0 trials
- Leukostasis 0 trials
- Pituitary gland basophil adenoma 0 trials
- Small intestinal enteropathy-associated T-cell lymphoma 0 trials
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Immune system cancer 0 trials · 3,127 incl. sub-types
25 sub-types
- Bone marrow cancer 2 trials · 1,633 incl. sub-types Sub-types →
- Plasma cell myeloma 1,108 trials · 1,131 incl. sub-types Sub-types →
- Thymus cancer 10 trials · 225 incl. sub-types Sub-types →
- Primary central nervous system lymphoma 92 trials · 103 incl. sub-types Sub-types →
- Lymphatic system cancer 4 trials · 70 incl. sub-types Sub-types →
- Dendritic cell sarcoma 0 trials · 53 incl. sub-types Sub-types →
- B-cell childhood acute lymphoblastic leukemia 37 trials
- T-cell childhood acute lymphocytic leukemia 10 trials
- Waldeyer's ring cancer 0 trials · 8 incl. sub-types Sub-types →
- Subcutaneous panniculitis-like T-cell lymphoma 8 trials
- Primary vitreoretinal large b-cell lymphoma 3 trials
- Indolent primary cutaneous B-cell lymphoma 1 trial · 2 incl. sub-types Sub-types →
- Systemic Epstein-Barr virus-positive T-cell lymphoproliferative disease of childhood 2 trials
- Breast diffuse large B-cell lymphoma 1 trial
- Colon Burkitt lymphoma 0 trials
- Colorectal diffuse large B-cell lymphoma 0 trials
- Gastric mantle cell lymphoma 0 trials
- Liver diffuse large B-cell lymphoma 0 trials
- Mast cell sarcoma 0 trials
- Primary pulmonary diffuse large B-cell lymphoma 0 trials
- Small intestinal Burkitt lymphoma 0 trials
- Small intestinal diffuse large B-cell lymphoma 0 trials
- Small intestinal enteropathy-associated T-cell lymphoma 0 trials
- Solitary plasmacytoma of chest wall 0 trials
- Thyroid gland diffuse large B-cell lymphoma 0 trials
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Bone marrow disorder 18 trials · 1,763 incl. sub-types
7 sub-types
- Bone marrow neoplasm 3 trials · 1,633 incl. sub-types Sub-types →
- Polycythemia 9 trials · 99 incl. sub-types Sub-types →
- Bone marrow failure syndrome 48 trials Sub-types →
- Osteomyelitis 43 trials · 46 incl. sub-types Sub-types →
- Fanconi anemia 29 trials · 42 incl. sub-types Sub-types →
- Drachtman Weinblatt Sitarz syndrome 0 trials
- Premature ovarian failure 15 0 trials
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Inflammatory bowel disease 430 trials · 1,081 incl. sub-types
40 sub-types
- Colitis 41 trials · 679 incl. sub-types Sub-types →
- Crohn disease 563 trials · 569 incl. sub-types Sub-types →
- Proctitis 2 trials · 21 incl. sub-types Sub-types →
- Inflammatory bowel disease 1 3 trials
- Undetermined colitis 3 trials
- Ulcerative proctosigmoiditis 2 trials
- ALPI-related inflammatory bowel disease 0 trials
- IL10-related early-onset inflammatory bowel disease 0 trials Sub-types →
- TRIM22-related inflammatory bowel disease 0 trials
- Cap polyposis 0 trials
- Cutaneous photosensitivity-lethal colitis syndrome 0 trials
- Inflammatory bowel disease (infantile ulcerative colitis) 31, autosomal recessive 0 trials
- Inflammatory bowel disease 10 0 trials
- Inflammatory bowel disease 11 0 trials
- Inflammatory bowel disease 12 0 trials
- Inflammatory bowel disease 13 0 trials
- Inflammatory bowel disease 14 0 trials
- Inflammatory bowel disease 15 0 trials
- Inflammatory bowel disease 16 0 trials
- Inflammatory bowel disease 17 0 trials
- Inflammatory bowel disease 18 0 trials
- Inflammatory bowel disease 19 0 trials
- Inflammatory bowel disease 2 0 trials
- Inflammatory bowel disease 20 0 trials
- Inflammatory bowel disease 21 0 trials
- Inflammatory bowel disease 22 0 trials
- Inflammatory bowel disease 23 0 trials
- Inflammatory bowel disease 24 0 trials
- Inflammatory bowel disease 26 0 trials
- Inflammatory bowel disease 27 0 trials
- Inflammatory bowel disease 29 0 trials
- Inflammatory bowel disease 3 0 trials
- Inflammatory bowel disease 30 0 trials
- Inflammatory bowel disease 4 0 trials
- Inflammatory bowel disease 5 0 trials
- Inflammatory bowel disease 6 0 trials
- Inflammatory bowel disease 7 0 trials
- Inflammatory bowel disease 8 0 trials
- Inflammatory bowel disease 9 0 trials
- Neonatal inflammatory skin and bowel disease 0 trials Sub-types →
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Hypersensitivity reaction disease 32 trials · 1,025 incl. sub-types
10 sub-types
- Allergic disease 179 trials · 969 incl. sub-types Sub-types →
- Anaphylaxis 26 trials · 27 incl. sub-types Sub-types →
- Type IV hypersensitivity disease 0 trials · 18 incl. sub-types Sub-types →
- Hypersensitivity vasculitis 0 trials · 16 incl. sub-types Sub-types →
- Immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome 10 trials
- IgE responsiveness, atopic 9 trials
- Type III hypersensitivity disease 3 trials · 6 incl. sub-types Sub-types →
- Progestogen hypersensitivity 3 trials
- Pseudoallergy 0 trials Sub-types →
- Type II hypersensitivity reaction disease 0 trials
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Immunodeficiency disease 55 trials · 779 incl. sub-types
95 sub-types
- T-cell immunodeficiency 4 trials · 484 incl. sub-types Sub-types →
- B cell deficiency 5 trials · 86 incl. sub-types Sub-types →
- Myalgic encephalomeyelitis/chronic fatigue syndrome 75 trials
- Combined immunodeficiency 3 trials · 57 incl. sub-types Sub-types →
- Complement deficiency 2 trials · 28 incl. sub-types Sub-types →
- X-linked lymphoproliferative syndrome 7 trials · 11 incl. sub-types Sub-types →
- GATA2 deficiency with susceptibility to MDS/AML 5 trials · 8 incl. sub-types Sub-types →
- Idiopathic CD4 lymphocytopenia 7 trials
- IKBKG-related immunodeficiency with or without ectodermal dysplasia 0 trials · 4 incl. sub-types Sub-types →
- Immunodeficiency due to selective anti-polysaccharide antibody deficiency 2 trials
- IRF4-related immune disorder 1 trial Sub-types →
- PTEN harmartoma tumor syndrome with immune disorder 1 trial
- Immunodeficiency 23 1 trial
- Immunodeficiency 31B 1 trial
- DNAJC21-related Shwachman Diamond syndrome 0 trials
- DOCK2 deficiency 0 trials
- FADD-related immunodeficiency 0 trials
- FASLG-related immunodeficiency 0 trials
- FNIP1-associated syndrome 0 trials
- Shwachman-Diamond syndrome 1 0 trials
- TFRC-related combined immunodeficiency 0 trials
- TNFRSF9-related immunodeficiency 0 trials Sub-types →
- Wiskott-Aldrich syndrome 2 0 trials
- Wiskott-Aldrich syndrome, autosomal dominant form 0 trials
- Autoimmune hemolytic anemia-autoimmune thrombocytopenia-primary immunodeficiency syndrome 0 trials
- Chronic mucocutaneous candidiasis and connective tissue disease due to JNK1 haploinsufficiency 0 trials
- Cryptosporidiosis-chronic cholangitis-liver disease syndrome 0 trials
- Hatipoglu immunodeficiency syndrome 0 trials
- Hypoproteinemia, hypercatabolic 0 trials
- Immune deficiency due to impaired neutrophil phagocytosis and migration 0 trials
- Immunodeficiency 101 (varicella zoster virus-specific) 0 trials
- Immunodeficiency 102 0 trials
- Immunodeficiency 106, susceptibility to viral infections 0 trials
- Immunodeficiency 107, susceptibility to invasive staphylococcus aureus infection 0 trials
- Immunodeficiency 112 0 trials
- Immunodeficiency 113 with autoimmunity and autoinflammation 0 trials
- Immunodeficiency 114, folate-responsive 0 trials
- Immunodeficiency 115 with autoinflammation 0 trials
- Immunodeficiency 117 0 trials
- Immunodeficiency 118 0 trials
- Immunodeficiency 119 0 trials
- Immunodeficiency 11b with atopic dermatitis 0 trials
- Immunodeficiency 121 with autoinflammation 0 trials
- Immunodeficiency 122 0 trials
- Immunodeficiency 123 with HPV-related verrucosis 0 trials
- Immunodeficiency 125 0 trials
- Immunodeficiency 126, susceptibility to 0 trials
- Immunodeficiency 127 0 trials
- Immunodeficiency 128 0 trials
- Immunodeficiency 132b 0 trials
- Immunodeficiency 133 with ectodermal dysplasia with or without peripheral neuropathy 0 trials
- Immunodeficiency 134 (Epstein-Barr virus-specific) 0 trials
- Immunodeficiency 14b, autosomal recessive 0 trials
- Immunodeficiency 15a 0 trials
- Immunodeficiency 35 0 trials
- Immunodeficiency 45 0 trials
- Immunodeficiency 53 0 trials
- Immunodeficiency 57 0 trials
- Immunodeficiency 60 0 trials
- Immunodeficiency 62 0 trials
- Immunodeficiency 63 with lymphoproliferation and autoimmunity 0 trials
- Immunodeficiency 64 0 trials
- Immunodeficiency 65, susceptibility to viral infections 0 trials
- Immunodeficiency 66 0 trials
- Immunodeficiency 67 0 trials
- Immunodeficiency 69 0 trials
- Immunodeficiency 70 0 trials
- Immunodeficiency 72 with autoinflammation 0 trials
- Immunodeficiency 74, COVID-19-related, X-linked 0 trials
- Immunodeficiency 75 0 trials
- Immunodeficiency 76 0 trials
- Immunodeficiency 77 0 trials
- Immunodeficiency 78 with autoimmunity and developmental delay 0 trials
- Immunodeficiency 80 with or without congenital cardiomyopathy 0 trials
- Immunodeficiency 81 0 trials
- Immunodeficiency 82 with systemic inflammation 0 trials
- Immunodeficiency 84 0 trials
- Immunodeficiency 85 and autoimmunity 0 trials
- Immunodeficiency 86 0 trials
- Immunodeficiency 87 and autoimmunity 0 trials
- Immunodeficiency 88 0 trials
- Immunodeficiency 89 and autoimmunity 0 trials
- Immunodeficiency 91 and hyperinflammation 0 trials
- Immunodeficiency 92 0 trials
- Immunodeficiency 93 and hypertrophic cardiomyopathy 0 trials
- Immunodeficiency 95 0 trials
- Immunodeficiency 96 0 trials
- Immunodeficiency 97 with autoinflammation 0 trials
- Immunodeficiency 98 with autoinflammation, X-linked 0 trials
- Immunodeficiency 99 with hypogammaglobulinemia and autoimmune cytopenias 0 trials
- Immunodeficiency due to CD25 deficiency 0 trials
- Lymphoproliferative syndrome 1 0 trials
- Primary immunodeficiency due to calcium channel deficiency 0 trials
- Primary immunodeficiency with natural-killer cell deficiency and adrenal insufficiency 0 trials
- Pyogenic bacterial infections due to MyD88 deficiency 0 trials
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Lymphoid system disorder 1 trial · 749 incl. sub-types
5 sub-types
- Lymphatic system disorder 31 trials · 711 incl. sub-types Sub-types →
- Tonsillitis 23 trials · 28 incl. sub-types Sub-types →
- Waldeyer's ring cancer 0 trials · 8 incl. sub-types Sub-types →
- Tonsil neoplasm 0 trials · 8 incl. sub-types Sub-types →
- Peritonsillar abscess 4 trials
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Psoriasis 381 trials
3 sub-types
- Pustular psoriasis 6 trials · 39 incl. sub-types Sub-types →
- Guttate psoriasis 2 trials
- Psoriasis 2 0 trials
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Inborn error of immunity 121 trials · 345 incl. sub-types
40 sub-types
- Lymphoproliferative syndrome 70 trials · 100 incl. sub-types Sub-types →
- B cell deficiency 5 trials · 86 incl. sub-types Sub-types →
- Phagocyte bactericidal dysfunction 0 trials · 37 incl. sub-types Sub-types →
- Complement deficiency 2 trials · 28 incl. sub-types Sub-types →
- Hereditary hemophagocytic lymphohistiocytosis 8 trials · 16 incl. sub-types Sub-types →
- Aicardi-Goutieres syndrome 9 trials Sub-types →
- Familial isolated congenital asplenia 6 trials
- Chronic mucocutaneous candidiasis 4 trials Sub-types →
- Immunoglobulin heavy chain deficiency 0 trials · 2 incl. sub-types Sub-types →
- A20 haploinsufficiency 1 trial
- BENTA disease 1 trial
- Immuno-osseous dysplasia 0 trials · 1 incl. sub-types Sub-types →
- Immunodysregulation with variable immunodeficiency and autoimmunity 1 trial
- IL10-related early-onset inflammatory bowel disease 0 trials Sub-types →
- NK cell deficiency 0 trials
- Say-Barber-Miller syndrome 0 trials
- T cell and NK cell immunodeficiency 0 trials
- T-cell immunodeficiency with epidermodysplasia verruciformis 0 trials
- X-linked immunoneurologic disorder 0 trials
- Autosomal recessive primary immunodeficiency with defective spontaneous natural killer cell cytotoxicity 0 trials
- Combined immunodeficiency due to moesin deficiency 0 trials
- Combined immunodeficiency with faciooculoskeletal anomalies 0 trials
- Dendritic cell deficiency 0 trials
- Ectodermal dysplasia and immune deficiency 0 trials Sub-types →
- Hepatic veno-occlusive disease-immunodeficiency syndrome 0 trials
- Immune dysregulation with immunodeficiency due to AIOLOS haploinsufficiency 0 trials
- Immune dysregulation-inflammatory bowel disease-arthritis-recurrent infections-lymphopenia syndrome 0 trials
- Immunodeficiency 28 0 trials
- Immunodeficiency 33 0 trials
- Immunodeficiency 37 0 trials Sub-types →
- Immunodeficiency 39 0 trials
- Immunodeficiency 47 0 trials
- Immunodeficiency 49 0 trials
- Immunodeficiency with defective T-cell response to interleukin 1 0 trials
- Immunodeficiency, X-linked, with deficiency of 115,000 Dalton surface glycoprotein 0 trials
- Inflammatory bowel disease-recurrent sinopulmonary infections syndrome 0 trials
- Primary immunodeficiency with post-measles-mumps-rubella vaccine viral infection 0 trials
- Properdin deficiency, X-linked 0 trials
- Recurrent infections associated with rare immunoglobulin isotypes deficiency 0 trials
- Trichohepatoenteric syndrome 0 trials Sub-types →
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Graft versus host disease 186 trials · 300 incl. sub-types
2 sub-types
- Chronic graft versus host disease 118 trials
- Acute graft versus host disease 86 trials
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Thymus gland disorder 1 trial · 240 incl. sub-types
3 sub-types
- Thymus neoplasm 5 trials · 240 incl. sub-types Sub-types →
- Ectopic thymus 0 trials
- Thymic dysplasia 0 trials
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Spondyloarthropathy 122 trials · 199 incl. sub-types
3 sub-types
- Ankylosing spondylitis 110 trials · 114 incl. sub-types Sub-types →
- Kummell disease 1 trial
- Hypermobility of coccyx 0 trials
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Thrombocytopenic purpura 8 trials · 116 incl. sub-types
2 sub-types
- Autoimmune thrombocytopenic purpura 95 trials
- Thrombotic thrombocytopenic purpura 15 trials · 20 incl. sub-types Sub-types →
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Granulomatosis with polyangiitis 95 trials · 115 incl. sub-types
1 sub-type
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Phagocytic cell dysfunction 1 trial · 77 incl. sub-types
7 sub-types
- Langerhans cell histiocytosis 40 trials · 41 incl. sub-types Sub-types →
- Defective phagocytic cell engulfment 0 trials · 37 incl. sub-types Sub-types →
- Phagocyte bactericidal dysfunction 0 trials · 37 incl. sub-types Sub-types →
- Defective phagocytic cell chemotaxis 0 trials
- Defective phagocytic cell opsonization 0 trials
- Familial lipochrome histiocytosis 0 trials
- Phagocytosis, plasma-related defect 1N 0 trials
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Cytokine release syndrome 33 trials
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Immunoproliferative disorder 19 trials
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Familial Mediterranean fever 15 trials
2 sub-types
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Immunodeficiency-related disorder 1 trial · 15 incl. sub-types
1 sub-type
- AIDS-related disorder 3 trials · 14 incl. sub-types Sub-types →
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Twin to twin transfusion syndrome 14 trials
1 sub-type
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22q11.2 deletion syndrome 7 trials · 13 incl. sub-types
4 sub-types
- DiGeorge syndrome 11 trials
- Velocardiofacial syndrome 4 trials
- Chromosome 22q11.2 deletion syndrome, distal 0 trials
- Congenital unilateral hypoplasia of depressor anguli oris 0 trials
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Cryopyrin-associated periodic syndrome 10 trials
3 sub-types
- CINCA syndrome 4 trials
- Muckle-Wells syndrome 3 trials
- Familial cold autoinflammatory syndrome 3 trials Sub-types →
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Acquired immunodeficiency 5 trials
2 sub-types
- Good syndrome 0 trials
- Acquired adult-onset immunodeficiency 0 trials
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Anti-HLA hyperimmunization 3 trials
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6 sub-types
- Proteasome-associated autoinflammatory syndrome 1 1 trial
- Proteasome-associated autoinflammatory syndrome 2 0 trials
- Proteasome-associated autoinflammatory syndrome 3 0 trials
- Proteasome-associated autoinflammatory syndrome 4 0 trials
- Proteasome-associated autoinflammatory syndrome 5 0 trials
- Proteasome-associated autoinflammatory syndrome 6 0 trials
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Roifman syndrome 1 trial
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Aggressive insulitis 1 trial
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Transcobalamin II deficiency 1 trial
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CADINS disease 0 trials
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Vici syndrome 0 trials
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Autosomal recessive osteopetrosis 7 0 trials
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Benign insulitis 0 trials
-
Cytokine receptor deficiency 0 trials
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Epidermodysplasia verruciformis 0 trials
1 sub-type
-
Erythroderma desquamativum 0 trials
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Immune system organ benign neoplasm 0 trials
3 sub-types
- Benign neoplasm of lymph node 0 trials
- Benign neoplasm of spleen 0 trials Sub-types →
- Benign neoplasm of thymus 0 trials Sub-types →
Most studied deeper sub-types
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Could a stem cell transplant cure immune diseases?
Cure Recruiting nowThis study tests whether a stem cell transplant can cure people with serious immune system disorders. Participants, aged 4 to 69, receive healthy donor stem cells to rebuild their immune system. The goal is to see if the transplant can permanently fix the immune defect and elimin…
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Cure
Last updated Aug 21, 2026 00:00 UTC
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New injection aims to stabilize platelets in chronic ITP patients
Disease control Recruiting nowThis Phase 3 trial tests whether mezagitamab, given as a shot under the skin, can safely keep platelet counts stable in adults with chronic ITP. ITP is a condition where the immune system destroys platelets, leading to easy bruising and bleeding. The study will compare mezagitama…
Phase 3 • Sponsor: Takeda • Aim: Disease control
Last updated Sep 20, 2026 00:00 UTC
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Can a donor stem cell transplant fix broken immune systems?
Disease control Recruiting nowThis study tests whether a stem cell transplant from a healthy donor can help people with severe primary immunodeficiencies. Participants aged 4 to 75 receive chemotherapy before the transplant to prepare their body. The goal is to see if the procedure is safe and can improve imm…
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Sep 20, 2026 00:00 UTC
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Could a metabolic modulator help people with type 1 diabetes use insulin better?
Disease control Recruiting nowThis study tests whether a drug called AMX0035 can improve how the body responds to insulin in adults with type 1 diabetes. Participants take either AMX0035 or a placebo daily for 24 weeks. Researchers measure insulin sensitivity using a glucose clamp test and track blood sugar c…
Phase 2 • Sponsor: University of Washington • Aim: Disease control
Last updated Sep 17, 2026 00:00 UTC
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New hope for rare blood cancer: experimental drug targets mast cells
Disease control Recruiting nowThis study tests an experimental drug called CGT9486 (bezuclastinib) in people with advanced systemic mastocytosis, a rare and serious blood disorder. The drug aims to control the disease by blocking a key protein that drives abnormal mast cell growth. About 140 adults with aggre…
Phase 2 • Sponsor: Cogent Biosciences, Inc. • Aim: Disease control
Last updated Sep 17, 2026 00:00 UTC
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A handful of peanuts a day might keep stress at bay
Disease control Recruiting nowThis trial investigates whether eating a daily serving of peanuts can reduce stress and improve markers of heart health in adults who report high stress levels. Participants will eat either peanuts or a calorie-matched snack for a period, while researchers measure changes in stre…
Sponsor: USDA, Western Human Nutrition Research Center • Aim: Disease control
Last updated Sep 13, 2026 00:00 UTC
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Gene therapy breakthrough targets kidney disease in High-Risk patients
Disease control Recruiting nowThis study tests a new gene therapy, PS-002, for adults with IgA nephropathy, a kidney disease that can lead to kidney failure. The therapy aims to control the disease in people who are at high risk of getting worse despite current treatments. Participants receive a single dose a…
Phase 1/2 • Sponsor: Purespring Therapeutics Limited • Aim: Disease control
Last updated Sep 11, 2026 00:00 UTC
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New shot shows promise for Long-Term control of bleeding disorder
Disease control Recruiting nowThis study tests the long-term safety of a drug called mezagitamab for adults with chronic immune thrombocytopenia (ITP), a condition where the immune system destroys platelets, causing easy bruising and bleeding. About 150 participants who completed earlier mezagitamab studies w…
Phase 3 • Sponsor: Takeda • Aim: Disease control
Last updated Sep 11, 2026 00:00 UTC
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Can a new injection calm severe eczema when creams fall short?
Disease control Recruiting nowThis study tests whether an investigational drug called tilrekimig, given as injections alongside medicated creams or ointments, can improve moderate-to-severe eczema (atopic dermatitis) in people aged 12 and older. Participants will be randomly assigned to receive either tilreki…
Phase 3 • Sponsor: Pfizer • Aim: Disease control
Last updated Sep 06, 2026 00:00 UTC
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Gene therapy builds Cancer-Killing cells inside you – no lab needed
Disease control Recruiting nowThis early-stage trial tests a new gene therapy called KLN-1010 for people with multiple myeloma that has come back or stopped responding to treatment. Instead of removing cells and engineering them in a lab, this therapy works inside the body to create special immune cells that …
Phase 1 • Sponsor: Kelonia Therapeutics, Inc. • Aim: Disease control
Last updated Aug 30, 2026 00:00 UTC
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Double attack: new CAR t therapy targets two cancer proteins in aggressive lymphoma
Disease control Recruiting nowThis study tests a new treatment called rondecabtagene autoleucel (ronde-cel) for people with aggressive B-cell non-Hodgkin lymphoma that has come back or not responded to prior therapy. Ronde-cel is a CAR T-cell therapy that targets two proteins (CD19 and CD20) on cancer cells. …
Phase 1/2 • Sponsor: Lyell Immunopharma, Inc. • Aim: Disease control
Last updated Aug 27, 2026 00:00 UTC
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New drug KK2223 enters early human testing for Tough-to-Treat T-Cell lymphoma
Disease control Recruiting nowThis early-stage trial is testing an experimental drug called KK2223 in 72 adults with T-cell lymphoma (a type of blood cancer) that has returned or not responded to prior treatments. The main goals are to check the drug's safety, find the best dose, and see how the body processe…
Phase 1 • Sponsor: Kyowa Kirin, Inc. • Aim: Disease control
Last updated Aug 23, 2026 00:00 UTC
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Pig cell transplant trial aims to stop severe low blood sugar in type 1 diabetes
Disease control Recruiting nowThis early-phase study tests a new treatment called OPF-310, which uses pig islet cells enclosed in a protective capsule, for people with unstable type 1 diabetes who still experience severe low blood sugar episodes despite using an automated insulin pump and continuous glucose m…
Phase 1/2 • Sponsor: Otsuka Pharmaceutical Factory, Inc. • Aim: Disease control
Last updated Aug 23, 2026 00:00 UTC
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New hope for giant cell arteritis patients?
Disease control Recruiting nowThis study tests whether the drug abatacept can help people with giant cell arteritis, a condition that causes inflammation in blood vessels. About 78 adults with newly diagnosed or relapsing disease will receive either abatacept or a placebo for up to 12 months. The goal is to s…
Phase 3 • Sponsor: University of Pennsylvania • Aim: Disease control
Last updated Aug 22, 2026 00:00 UTC
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New hope for kidney disease: JADE101 trial launches
Disease control Recruiting nowThis study tests a new drug, JADE101, in 30 adults with IgA nephropathy, a kidney disease. The goal is to see if the drug is safe and can reduce protein in the urine, a sign of kidney damage. Participants must be on stable standard care and have a kidney biopsy confirming the dis…
Phase 2 • Sponsor: Jade Biosciences, Inc. • Aim: Disease control
Last updated Aug 22, 2026 00:00 UTC
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New pill aims to shrink Hard-to-Treat cancers
Disease control Recruiting nowThis study tests an experimental drug called Tulmimetostat (DZR123) in people with advanced solid tumors or lymphomas that have not improved with standard treatments. The drug is taken as a daily pill, either alone or combined with another drug (enzalutamide) for certain prostate…
Phase 1/2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Aug 21, 2026 00:00 UTC
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New hope for kidney disease: Zigakibart's Long-Term safety under study
Disease control Recruiting nowThis study looks at the long-term safety of a drug called zigakibart for adults with IgA nephropathy, a kidney disease. It is for people who have already finished a previous zigakibart study. Researchers will monitor side effects and check kidney function over 96 weeks.
Phase 3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Aug 19, 2026 00:00 UTC
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New eczema drug shows promise in Mid-Stage trial
Disease control Recruiting nowThis study tests whether IMG-007 can safely reduce eczema symptoms like itching and redness in adults with moderate-to-severe disease who haven't responded well to topical treatments. About 405 participants will receive either the drug or a placebo, and researchers will measure s…
Phase 2 • Sponsor: Inmagene LLC • Aim: Disease control
Last updated Aug 14, 2026 00:00 UTC
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New cell therapy aims to make stem cell transplants safer for blood cancer patients
Disease control Recruiting nowThis phase 2 trial is testing a new treatment called Orca-T for people with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). Orca-T is a personalized cell therapy made from a donor's blood that includes stem cells and immune cells. The goal is to see if it can impr…
Phase 2 • Sponsor: Orca Biosystems, Inc. • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
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New drug aims to calm immune attacks on kidneys
Disease control Recruiting nowThis Phase 2 study tests atacicept, a drug that may reduce immune system attacks on the kidneys. About 250 adults with various autoimmune kidney diseases (like IgA nephropathy or membranous nephropathy) will receive weekly injections. Researchers will check safety and measure cha…
Phase 2 • Sponsor: Vera Therapeutics, Inc. • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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CAR-T therapy takes on lupus and scleroderma in early trial
Disease control Recruiting nowThis early-phase trial is testing a new treatment called zamto-cel, a CAR-T cell therapy, for people with severe lupus or scleroderma that hasn't improved with standard treatments. The study will enroll 48 participants and primarily look at safety and side effects. Participants f…
Phase 1 • Sponsor: Miltenyi Biomedicine GmbH • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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Experimental immune therapy takes on tough lymphomas
Disease control Recruiting nowThis early-phase trial is testing a new cell therapy called TBI-2001 for people with certain blood cancers (B-cell lymphoma, CLL, SLL) that have come back or not responded to at least two prior treatments. The therapy uses a patient's own immune cells, modified to recognize and a…
Phase 1 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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Zinc pills tested as shield against toxic mine waste on navajo land
Disease control Recruiting nowThis study is testing whether taking a daily zinc supplement can reduce the harmful effects of metal exposure from old mine waste. About 100 adults from Navajo communities will take zinc and have their blood and urine tested for signs of metal toxicity and immune system changes. …
Phase 2 • Sponsor: University of New Mexico • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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New drug shows promise for kidney disease patients
Disease control Recruiting nowThis study tests a drug called sparsentan in 24 adults with IgA nephropathy, a kidney disease. Some participants are newly diagnosed, others have the disease return after a kidney transplant. The goal is to see if sparsentan can reduce protein in the urine, a sign of kidney damag…
Phase 2 • Sponsor: University of Leicester • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New drug combo aims to tame inflammation before stem cell transplant
Disease control Recruiting nowThis phase 2 study tests whether giving emapalumab or a combination of fludarabine and dexamethasone before a stem cell transplant can reduce inflammation and help the donated cells take hold better. The trial involves 39 people with primary immune regulatory disorders or autoinf…
Phase 2 • Sponsor: Joseph Oved • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New bone marrow transplant trial offers hope for kids with severe blood disorders
Disease control Recruiting nowThis study tests a bone marrow transplant from a family donor for children under 21 with severe non-cancer blood disorders like sickle cell disease, bone marrow failure, or immune problems. The goal is to see if the transplant can replace the diseased cells with healthy donor cel…
Phase 1/2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Immune cell therapy takes on rare blistering skin disease
Disease control Recruiting nowThis study tests two types of engineered immune cells (CAR T cells) in 40 adults with active pemphigus vulgaris, a painful blistering skin condition. The cells are designed to target and reduce the faulty immune cells that attack the skin. The main goal is to check safety and fin…
Phase 1/2 • Sponsor: Cabaletta Bio • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Stem cell transplant offers new hope for rare immune diseases
Disease control Recruiting nowThis study tests a stem cell transplant for people with common variable immunodeficiency (CVID) and other immune disorders. The goal is to replace the faulty immune system with a healthy donor's stem cells. Participants are aged 5 to 40 and will receive a reduced-intensity transp…
Phase 2 • Sponsor: Paul Szabolcs • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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Could a common diabetes drug tame inflammation in drug users?
Disease control Recruiting nowThis study tests whether metformin, a common diabetes drug, can reduce harmful inflammation and improve immune function in 100 adults aged 18-64 who have a history of injection drug use, some of whom also have HIV. Participants take metformin or a placebo for 16 weeks and receive…
Phase 4 • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New pill combo shows promise for tough brain cancer
Disease control Recruiting nowThis study tests an experimental oral drug called emavusertib (CA-4948), taken alone or with ibrutinib, in adults with relapsed or refractory primary central nervous system lymphoma (PCNSL). The trial has multiple parts to find the safest dose and see if the drug shrinks tumors. …
Phase 1/2 • Sponsor: Curis, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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Can a 9-Minute chat help black adults breathe easier?
Disease control Recruiting nowThis study tests a short, scripted conversation between doctors and Black adults with uncontrolled asthma. The goal is to help patients and doctors make decisions together about asthma medicines. Researchers will enroll 400 adults at community health centers to see if this approa…
Sponsor: Columbia University • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Can a quick strike drug stop MS in its tracks?
Disease control Recruiting nowThis study tests whether giving the drug natalizumab (Tyruko) within two weeks of first MS symptoms can help repair nerve damage. Forty adults with a first episode of MS-like inflammation will receive either the drug or a placebo. The main goal is to see if early treatment improv…
Phase 2 • Sponsor: Queen Mary University of London • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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New drug vimseltinib aims to tame chronic GVHD in failed treatments
Disease control Recruiting nowThis study tests whether the drug vimseltinib is safe and effective for adults with moderate to severe chronic graft-versus-host disease (cGVHD) who have not improved after at least two prior treatments. About 48 participants will take vimseltinib daily for up to two years. The g…
Phase 2 • Sponsor: Deciphera Pharmaceuticals, LLC • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Can a website help tame type 1 diabetes? new study seeks answers
Disease control Recruiting nowThis study tests whether an online training and support platform can help adults with type 1 diabetes better manage their blood sugar and well-being. About 322 participants across Canada will use the platform for 12 months, either as part of their usual clinic care or on their ow…
Sponsor: McGill University • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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New online tool aims to ease tough transition for teens with diabetes
Disease control Recruiting nowThis study tests whether an online training and peer support platform (Support-t) helps teens with type 1 diabetes prepare for the move from pediatric to adult healthcare. About 200 teens aged 14-16 will either use the platform plus usual care or just usual care. The main goal is…
Sponsor: Anne-Sophie Brazeau • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Strumming for the brain: could ukulele lessons sharpen minds in MS?
Symptom relief Recruiting nowThis study tests whether a 12-week online ukulele learning program, called Music-4-MS, can improve cognitive function in people with multiple sclerosis (MS). Half the participants will learn to play the ukulele, while the other half will simply listen to music they enjoy. The goa…
Sponsor: University of Texas at Austin • Aim: Symptom relief
Last updated Aug 19, 2026 00:00 UTC
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Scientists launch national study to track immune weakness linked to severe COVID
Knowledge-focused Recruiting nowThis study follows 500 adults in France who have either a genetic defect or autoantibodies that weaken their type I interferon immune response. Researchers will collect blood samples and health data over 1 to 4 years to track infections, autoimmune diseases, and cancers. The goal…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Sep 20, 2026 00:00 UTC
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New biobank aims to unlock secrets of Immunotherapy's harsh side effects
Knowledge-focused Recruiting nowThis study collects blood, tissue, and medical information from 240 cancer patients who have had serious side effects from immunotherapy. The goal is to store these samples in a national biorepository for future research. By studying these samples, scientists hope to better predi…
Sponsor: Alliance for Clinical Trials in Oncology • Aim: Knowledge-focused
Last updated Sep 19, 2026 00:00 UTC
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Scientists dig into skin healing mysteries in immune disorders
Knowledge-focused Recruiting nowThis study aims to understand how the immune system and skin healing are connected in people with primary immunodeficiency, psoriasis, or eczema, as well as in healthy volunteers. Researchers will collect skin biopsies, blood samples, and optional skin swabs to analyze microbes a…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC
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NIH launches major screening study to unravel mysteries of immune weakness
Knowledge-focused Recruiting nowThis study screens up to 2,000 people who have or may have immune disorders that make them prone to infections, along with their healthy relatives. Researchers will use medical history, physical exams, blood tests, and genetic testing to better understand these conditions. The go…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC
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Scientists dig into mouth bacteria to unlock immune secrets
Knowledge-focused Recruiting nowThis study looks at how genetic immune system problems might lead to gum disease and other mouth issues. Researchers will collect samples like saliva, plaque, and blood from 700 people, including those with immune defects, healthy adults with gum disease, and healthy adults witho…
Sponsor: National Institute of Dental and Craniofacial Research (NIDCR) • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC
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Massive gene hunt aims to unlock secrets of immune disorders
Knowledge-focused Recruiting nowThis study is looking for the genes that cause certain immune system problems. Researchers want to understand why some people get sick and others don't, even in the same family. Up to 5,000 people with immune disorders and their relatives will give blood or cheek cell samples for…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC
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Massive study aims to unlock secrets of Brain's immune attacks
Knowledge-focused Recruiting nowThis observational study is recruiting 2400 people with immune-related central nervous system diseases, such as multiple sclerosis, along with healthy volunteers for comparison. Researchers will use MRI scans, lumbar punctures, blood tests, and neurological exams to track disease…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC
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Scientists seek clues on white blood cell behavior in allergies and parasites
Knowledge-focused Recruiting nowThis study aims to understand how and why eosinophils (a type of white blood cell) become active in conditions like allergies, asthma, and parasitic infections. Researchers will observe up to 800 people aged 1 to 100 with high eosinophil levels. No experimental treatments are giv…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC
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Scientists hunt for new immune disease genes in 500-Person study
Knowledge-focused Recruiting nowThis study aims to find new genes that cause immune system problems by examining up to 500 people with immune disorders and their relatives. Participants provide blood, saliva, or tissue samples and may have medical tests, but no experimental treatments are given. The goal is to …
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Sep 16, 2026 00:00 UTC
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Massive study aims to unravel mysteries of blood clots and vessel disease
Knowledge-focused Recruiting nowThis study aims to learn more about how diseases related to blood clots, the immune system, and blood vessels start and change over time. Researchers will enroll up to 1,000 people aged 5 and older, including those with these conditions, their healthy relatives, and healthy volun…
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Sep 12, 2026 00:00 UTC
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500-Patient study aims to unravel mysteries of rare immune diseases
Knowledge-focused Recruiting nowThis study follows 500 children and adults with rare genetic disorders called type I interferonopathies, which cause severe inflammation and neurological problems. Researchers will track how the disease progresses over time and look for biological markers to improve diagnosis and…
Sponsor: Imagine Institute • Aim: Knowledge-focused
Last updated Sep 12, 2026 00:00 UTC
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Military study probes Toxins' role in lymphoma
Knowledge-focused Recruiting nowThis observational study is recruiting 300 active-duty service members and military beneficiaries diagnosed with B-cell non-Hodgkin lymphoma. Researchers want to understand how exposure to toxins, genetic differences, and immune system problems are linked to this cancer. Particip…
Sponsor: Henry M. Jackson Foundation for the Advancement of Military Medicine • Aim: Knowledge-focused
Last updated Sep 05, 2026 00:00 UTC
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Scientists seek answers for rare immune disorder
Knowledge-focused Recruiting nowThis study aims to learn more about Hyper IgE syndrome, a rare immune disorder that causes skin and lung infections. Researchers will follow 600 patients and their relatives over time, examining their health and genetics. The goal is to better understand the disease and improve c…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Sep 02, 2026 00:00 UTC
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Scientists investigate hidden link between immune disorders and brain health
Knowledge-focused Recruiting nowThis study looks at how immune system diseases can cause problems in the brain and nerves, affecting movement, thinking, and feelings. Researchers will follow 350 people aged 2 and older with immune diseases, plus their healthy relatives, for up to 5 years. They will collect bloo…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Aug 07, 2026 00:00 UTC
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Blue-green algae protein put to the test: can it rev up immune cells?
Knowledge-focused Recruiting nowThis trial tests whether spirulina blue protein capsules can safely influence the immune system in healthy adults aged 25 to 60. Participants take either a placebo or one of two doses (200 mg or 1,000 mg daily) for 12 weeks. Researchers measure changes in key immune cells and blo…
Sponsor: University of Phayao • Aim: Knowledge-focused
Last updated Jul 31, 2026 00:00 UTC
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New study aims to spot lung trouble before it starts in transplant patients
Knowledge-focused Recruiting nowThis study looks for better ways to detect lung inflammation and infections early in people who have received a stem cell transplant from a donor. About 40 participants aged 5 to 70 will get regular lung scans, breathing tests, blood draws, and a procedure where a tube collects f…
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Jul 16, 2026 00:00 UTC
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Lupus patients enrolled in major Long-Term observation study
Knowledge-focused Recruiting nowThis study follows 300 adults with systemic lupus erythematosus (SLE) who are seen by a team of specialists at a hospital in Brest, France. Researchers will collect data on disease patterns, symptoms, and test results over time. The goal is to better understand lupus and improve …
Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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Hormone therapy's hidden impact on gut bugs and heart risk revealed in new study.
Knowledge-focused Recruiting nowThis study follows 200 healthy transgender people for five years after they start hormone replacement therapy. Researchers will track changes in gut bacteria, blood markers, and heart risk factors to understand how sex hormones influence the gut-heart connection. The goal is to l…
Sponsor: Charite University, Berlin, Germany • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Could a simple blood test explain why some women Can't carry a pregnancy?
Knowledge-focused Recruiting nowThis study is looking at whether immune system imbalances contribute to repeated IVF failure or unexplained miscarriages. Researchers will collect blood samples from 150 women (including healthy controls) to measure immune cell types and inflammatory markers. The goal is to ident…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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Scientists track Melanoma's metabolic tricks in tiny study
Knowledge-focused Recruiting nowThis study looks at melanoma tumors that spread between the main tumor and nearby lymph nodes (called in-transit metastases). Researchers will take biopsies from different spots and use a safe tracer to measure oxygen levels. They aim to understand how these tumors change metabol…
Sponsor: Yana Najjar • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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Scientists seek immune system clues from cancer patients and healthy volunteers
Knowledge-focused Recruiting nowThis research study collects blood, bone marrow, and tissue samples from people with cancer, blood disorders, and healthy volunteers. The goal is to study how the immune system changes during different treatments, including immunotherapy and chemotherapy. By comparing samples fro…
Sponsor: University of Southern California • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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Stomach stalling? new study eyes link between rare allergy and slow digestion
Knowledge-focused Recruiting nowThis study looks at whether eosinophilic gastritis, a rare stomach condition, causes problems with how the stomach moves food. Researchers will use a special scan after an oatmeal meal to check stomach emptying in 30 people. The goal is to better understand if these motility issu…
Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Can a simple questionnaire predict who will follow their treatment?
Knowledge-focused Recruiting nowThis study is testing a tool called B-COMPASS that uses a 22-question survey to predict whether people will follow their prescribed treatments. Researchers will enroll 3100 adults with cardiovascular, endocrine, immune, nerve, cancer, or rare diseases across Europe. The goal is t…
Sponsor: Technical University of Madrid • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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5,000 patients to help unlock secrets of kidney disease and transplant outcomes
Knowledge-focused Recruiting nowThis study will enroll 5,000 adults with kidney disease or at risk for it, including transplant recipients. Researchers will analyze blood and urine samples to find molecular patterns that predict disease progression, complications, or treatment response. The goal is to improve r…
Sponsor: University Hospital, Toulouse • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Arginine supplement may boost immunity in newborns after bowel surgery
Knowledge-focused Recruiting nowThis study tests whether giving extra arginine (a nutrient) to preterm and full-term infants after major bowel surgery or a serious gut infection (necrotising enterocolitis) can improve their immune function. Researchers will measure changes in gene activity related to infection-…
Sponsor: University of Liverpool • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Massive new registry aims to unlock secrets of biologic drugs
Knowledge-focused Recruiting nowThis study is creating a large registry of 800 people receiving biologic medications for immune conditions like autoimmune diseases and primary immune deficiencies. Researchers will collect blood samples and health data to better understand how these treatments work and who respo…
Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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Tiny study probes Electroacupuncture's immune effects in shingles
Knowledge-focused Recruiting nowThis study looks at how electroacupuncture might affect immune cells in people with shingles (herpes zoster). Researchers will compare standard medication alone versus medication plus electroacupuncture in 8 women aged 50-70. The goal is to see if electroacupuncture changes immun…
Sponsor: First People's Hospital of Hangzhou • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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New study aims to predict dangerous side effects of cancer immunotherapy
Knowledge-focused Recruiting nowThis study collects medical information and biological samples (blood, tissue, stool) from 1,000 cancer patients receiving immune checkpoint inhibitors. The goal is to understand why some patients develop immune-related side effects and find ways to predict and manage them. Parti…
Sponsor: Sir Mortimer B. Davis - Jewish General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Scientists dig into immune cells to unlock lung disease mysteries
Knowledge-focused Recruiting nowThis study looks at how immune cells behave in people with lung cancer, sarcoidosis, and COPD. Researchers will collect blood and tissue samples from 425 participants to analyze immune function. No experimental treatments are given. The goal is to understand why some patients don…
Sponsor: Université Catholique de Louvain • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Major study launches to unravel rare genetic diseases affecting immunity and the brain
Knowledge-focused Recruiting nowThis study aims to learn more about rare genetic diseases that affect both the immune system and the nervous system. Researchers will collect medical information and samples from 1,000 participants, including patients, their relatives, and healthy volunteers. The goal is to bette…
Sponsor: Imagine Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Sugar tracker: scientists spy on immune Cells' energy use
Knowledge-focused Recruiting nowThis study aims to understand how immune cells use glucose (sugar) for energy and building materials. Researchers will give 12 healthy adults a non-radioactive glucose tracer through an IV and then collect blood samples to track how different immune cells take up and process the …
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC