New drug KK2223 enters early human testing for Tough-to-Treat T-Cell lymphoma
NCT ID NCT07192471
First seen Jun 26, 2026 · Last updated Jul 02, 2026 · Updated 3 times
Summary
This early-stage trial is testing an experimental drug called KK2223 in 72 adults with T-cell lymphoma (a type of blood cancer) that has returned or not responded to prior treatments. The main goals are to check the drug's safety, find the best dose, and see how the body processes it. The study is not yet recruiting and will take place at multiple centers.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
KK2223 (an experimental drug given by IV infusion)
What this could lead to
If it works, this could point toward a new treatment option for people with T-cell lymphoma that has not responded to other therapies.
What could go wrong
This is a very early Phase 1 trial focused on safety and dosing, not on effectiveness. It is small (72 people) and may not lead to a proven treatment. Side effects are unknown.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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AOU Citta' della Salute e della Scienza di Torino Ospedale Molinette, Ematologia Universitaria
Torino, 10126, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Azienda Ospedaliera Papa Giovanni XXIII - Ematologia
Bergamo, 24127, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Azienda Ospedaliero Universitaria di Bologna IRCCS (Policlinico di Sant'Orsola) - Ematologia
Bologna, 40138, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Beth Israel Deaconess Medical Center - Research
Boston, Massachusetts, 02215, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Clinica Universidad de Navarra - Hematología
Pamplona, Navarre, 31008, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Clinica Universidad de Navarra - Hematología y Hemoterapia
Madrid, 28027, Spain
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hackensack University Medical Center - John Theurer Cancer C - Lymphoma Division
Hackensack, New Jersey, 07601-2105, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Clinic De Barcelona - Hematología
Badalona, Barcelona, 8036, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Institut Català d'Oncologia (ICO) - ICO L'Hospitalet - Hematologia
L'Hospitalet de Llobregat, Barcelona, 8907, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Istituto di Candiolo, IRCCS - Oncologia Medica ed Ematologia
Candiolo, Torino, 10060, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Memorial Sloan Kettering Cancer Center
New York, New York, 10021-6007, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Oregon Health & Science University
Portland, Oregon, 97239, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Stanford University School of Medicine
Stanford, California, 94305, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The University of Texas - MD Anderson Cancer Center
Houston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of California, Irvine Medical Center - Hematology/Oncology
Orange, California, 92868, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Pennsylvania - Abramson Cancer Center
Philadelphia, Pennsylvania, 19104, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Washington University School of Medicine - Oncology Hospital - Public
St Louis, Missouri, 63110, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact