Massive study aims to unlock secrets of Brain's immune attacks
NCT ID NCT00794352
First seen Jun 27, 2026 · Last updated Aug 05, 2026 · Updated 11 times
Summary
This observational study is recruiting 2400 people with immune-related central nervous system diseases, such as multiple sclerosis, along with healthy volunteers for comparison. Researchers will use MRI scans, lumbar punctures, blood tests, and neurological exams to track disease progression and identify biomarkers. The goal is to better understand how the immune system damages the brain and spinal cord, which could inform future diagnostic and treatment strategies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this study could identify new biomarkers and improve understanding of immune-related brain diseases, potentially guiding future treatments.
- What could go wrong
- This is an observational study, not a treatment trial. It may not directly lead to new therapies, and results may take years to translate into clinical practice.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
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