Scientists launch national study to track immune weakness linked to severe COVID

NCT ID NCT06762002

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study follows 500 adults in France who have either a genetic defect or autoantibodies that weaken their type I interferon immune response. Researchers will collect blood samples and health data over 1 to 4 years to track infections, autoimmune diseases, and cancers. The goal is to better understand and manage these immune deficiencies, but no new treatments are being tested.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could improve how doctors monitor and manage patients with type I interferon deficiencies, potentially reducing severe infections.

What could go wrong

This is an observational study, not a treatment trial. It will not directly cure or treat any disease, and results may take years to translate into clinical practice.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

allergic disease COVID-19 hereditary disease immune system disorder infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cic Bichat

    RECRUITING

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Cic Creteil

    RECRUITING

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Cic La Salpetriere

    RECRUITING

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Cic Lille

    RECRUITING

    Lille, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Cic Montpellier

    RECRUITING

    Montpellier, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Cic Necker

    RECRUITING

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Cic St Louis

    RECRUITING

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Cic Tours

    RECRUITING

    Tours, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • LYON HCL

    RECRUITING

    Lyon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact