NIH launches major screening study to unravel mysteries of immune weakness

NCT ID NCT00404560

First seen Jun 27, 2026 · Last updated Jul 29, 2026 · Updated 7 times

Summary

This study screens up to 2,000 people who have or may have immune disorders that make them prone to infections, along with their healthy relatives. Researchers will use medical history, physical exams, blood tests, and genetic testing to better understand these conditions. The goal is to improve diagnosis and guide future research, not to provide treatment directly.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could improve how doctors diagnose and understand immune disorders that make people prone to infections.
What could go wrong
This is an early screening study, not a treatment trial. It may not lead to direct benefits for participants, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.