Scientists seek answers for rare immune disorder

NCT ID NCT00006150

First seen Jun 24, 2026 · Last updated Jul 29, 2026 · Updated 11 times

Summary

This study aims to learn more about Hyper IgE syndrome, a rare immune disorder that causes skin and lung infections. Researchers will follow 600 patients and their relatives over time, examining their health and genetics. The goal is to better understand the disease and improve care, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could lead to better diagnosis, management, and understanding of Hyper IgE syndrome, potentially guiding future treatments.
What could go wrong
This is an observational study, not a treatment trial. It may not directly improve health for participants, and results may take years to translate into clinical practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.