Could a stem cell transplant fix broken immune systems?

NCT ID NCT07284641

First seen Jan 09, 2026 · Last updated May 18, 2026 · Updated 17 times

Summary

This study tests a stem cell transplant for people aged 5 to 40 with common variable immunodeficiency (CVID) or other immune regulation disorders. The goal is to replace faulty immune cells with healthy donor cells using a gentle chemotherapy and radiation preparation. While the transplant may improve immune function, participants may still need ongoing medication to manage their condition.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UPMC Children's Hospital of Pittsburgh

    RECRUITING

    Pittsburgh, Pennsylvania, 15224, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.