PRIMARY IMMUNE REGULATORY DISORDER
Clinical trials for PRIMARY IMMUNE REGULATORY DISORDER explained in plain language.
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New drug combo aims to tame inflammation before stem cell transplant
Disease control Recruiting nowThis phase 2 study tests whether giving emapalumab or a combination of fludarabine and dexamethasone before a stem cell transplant can reduce inflammation and help the donated cells take hold better. The trial involves 39 people with primary immune regulatory disorders or autoinf…
Matched conditions: PRIMARY IMMUNE REGULATORY DISORDER
Phase: PHASE2 • Sponsor: Joseph Oved • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Stem cell transplant offers new hope for rare immune diseases
Disease control Recruiting nowThis study tests a stem cell transplant for people with common variable immunodeficiency (CVID) and other immune disorders. The goal is to replace the faulty immune system with a healthy donor's stem cells. Participants are aged 5 to 40 and will receive a reduced-intensity transp…
Matched conditions: PRIMARY IMMUNE REGULATORY DISORDER
Phase: PHASE2 • Sponsor: Paul Szabolcs • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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New immune cell boost may shield kids from Post-Transplant infections
Disease control Recruiting nowThis study tests whether adding memory immune cells (CD45RO) to a stem cell transplant can help children fight off dangerous viral and fungal infections after the procedure. The transplant uses donor stem cells that have been stripped of certain cells to prevent graft-versus-host…
Matched conditions: PRIMARY IMMUNE REGULATORY DISORDER
Phase: PHASE1, PHASE2 • Sponsor: Children's Hospital of Philadelphia • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC