IMMUNE DYSREGULATION
Clinical trials for IMMUNE DYSREGULATION explained in plain language.
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Can calming the immune system save Kids' livers?
Disease control Recruiting nowThis study tests whether two drugs that calm the immune system—high-dose steroids or anti-thymocyte globulin—can help children with sudden, severe liver failure survive without needing a liver transplant. About 163 children aged 1 to 17 will be randomly assigned to receive one of…
Matched conditions: IMMUNE DYSREGULATION
Phase: PHASE2 • Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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Stem cell transplant offers new hope for rare immune diseases
Disease control Recruiting nowThis study tests a stem cell transplant for people with common variable immunodeficiency (CVID) and other immune disorders. The goal is to replace the faulty immune system with a healthy donor's stem cells. Participants are aged 5 to 40 and will receive a reduced-intensity transp…
Matched conditions: IMMUNE DYSREGULATION
Phase: PHASE2 • Sponsor: Paul Szabolcs • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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Could a common diabetes drug tame inflammation in drug users?
Disease control Recruiting nowThis study tests whether metformin, a common diabetes drug, can reduce harmful inflammation and improve immune function in 100 adults aged 18-64 who have a history of injection drug use, some of whom also have HIV. Participants take metformin or a placebo for 16 weeks and receive…
Matched conditions: IMMUNE DYSREGULATION
Phase: PHASE4 • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Military study probes Toxins' role in lymphoma
Knowledge-focused Recruiting nowThis observational study is recruiting 300 active-duty service members and military beneficiaries diagnosed with B-cell non-Hodgkin lymphoma. Researchers want to understand how exposure to toxins, genetic differences, and immune system problems are linked to this cancer. Particip…
Matched conditions: IMMUNE DYSREGULATION
Sponsor: Henry M. Jackson Foundation for the Advancement of Military Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Scientists dig into immune cells to unlock lung disease mysteries
Knowledge-focused Recruiting nowThis study looks at how immune cells behave in people with lung cancer, sarcoidosis, and COPD. Researchers will collect blood and tissue samples from 425 participants to analyze immune function. No experimental treatments are given. The goal is to understand why some patients don…
Matched conditions: IMMUNE DYSREGULATION
Phase: NA • Sponsor: Université Catholique de Louvain • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC