New shot shows promise for Long-Term control of bleeding disorder
NCT ID NCT06948318
First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 3 times
Summary
This study tests the long-term safety of a drug called mezagitamab for adults with chronic immune thrombocytopenia (ITP), a condition where the immune system destroys platelets, causing easy bruising and bleeding. About 150 participants who completed earlier mezagitamab studies will receive the drug as needed. Researchers will monitor side effects and how well the drug controls platelet levels over time.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
Locations
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A.O.U. Maggiore della Carita
RECRUITINGNovara, 28100, Italy
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AOU Citta della Salute e della Scienza di Torino
NOT_YET_RECRUITINGTorino, 10126, Italy
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ASST Grande Ospedale Metropolitano Niguarda - Presidio Ospedaliero Ospedale Niguarda
NOT_YET_RECRUITINGMilan, 20162, Italy
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American Oncology Partners of Maryland, PA
NOT_YET_RECRUITINGMorristown, New Jersey, 07960, United States
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Ankara University Faculty of Medicine Cebeci Hospital, Department of Hematology
NOT_YET_RECRUITINGMamak, Ankara, 6620, Turkey (Türkiye)
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Asan Medical Center
NOT_YET_RECRUITINGSeoul, 5505, South Korea
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Aydin Adnan Menderes University Medical Faculty-Hematology Department
NOT_YET_RECRUITINGEfeler, Aydın, 9100, Turkey (Türkiye)
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Azienda Ospedaliera Di Rilievo Nazionale E Di Alta Specializzazione Garibaldi
NOT_YET_RECRUITINGCatania, Sicily, 95122, Italy
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Azienda Ospedaliera Universitaria Federico II
NOT_YET_RECRUITINGNaples, Campania, 80131, Italy
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Azienda Ospedaliera Universitaria Policlinico Sant'Orsola Malpighi
NOT_YET_RECRUITINGBologna, 40123, Italy
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Azienda Ospedaliera Universitaria Policlinico Tor Vergata
NOT_YET_RECRUITINGRome, oo133, Italy
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Azienda ULSS 8 Berica - Ospedale San Bortolo
RECRUITINGVicenza, 36100, Italy
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Azienda sanitaria universitaria Giuliano Isontina
RECRUITINGTrieste, 34129, Italy
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Barts Health NHS Trust, Royal London Hospital
RECRUITINGLondon, E11BB, United Kingdom
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Baylor College of Medicine
NOT_YET_RECRUITINGHouston, Texas, 77030, United States
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C.A.U de Burgos - Hospital Universitario de Burgos
NOT_YET_RECRUITINGBurgos, 9006, Spain
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Canberra Hospital
RECRUITINGGarran, Australian Capital Territory, 2605, Australia
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Cerrahpasa Tip Fakultesi
NOT_YET_RECRUITINGEdirne, 22030, Turkey (Türkiye)
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Chiba Aoba Municipal Hospital
NOT_YET_RECRUITINGChuo-ku, Chiba, 260-0852, Japan
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Chibaken Saiseikai Narashino Hospital
NOT_YET_RECRUITINGNarashino-shi, Chiba, 275-8580, Japan
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Clinical Hospital Centar Zagreb
NOT_YET_RECRUITINGZagreb, 10000, Croatia
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Concord Repatriation General Hospital
NOT_YET_RECRUITINGConcord, New South Wales, 2139, Australia
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Duke University Hospital
NOT_YET_RECRUITINGDurham, North Carolina, 27710, United States
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East Carolina University
NOT_YET_RECRUITINGGreenville, North Carolina, 27837, United States
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Emory University
NOT_YET_RECRUITINGAtlanta, Georgia, 30308, United States
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Erasmus Medical Center, Department of Hematology
NOT_YET_RECRUITINGRotterdam, South Holland, 3015 GD, Netherlands
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Fiona Stanley Hospital
NOT_YET_RECRUITINGMurdoch, Western Australia, 6150, Australia
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Fondazione IRCCS San Gerardo Dei Tintori
NOT_YET_RECRUITINGMonza, 20900, Italy
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General Hospital of Thessaloniki George Papanikolaou
RECRUITINGThessaloniki, Greece
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Genesis Cancer and Blood Institute - SCRI
NOT_YET_RECRUITINGHot Springs, Arkansas, 71913, United States
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Georgetown University Medical Center - Lombardi Comprehensive Cancer Center
NOT_YET_RECRUITINGWashington D.C., District of Columbia, 20007, United States
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Greater Glasgow Health Board
NOT_YET_RECRUITINGGlasgow, Scotland, G312ER, United Kingdom
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Guangdong Provincial People's Hospital
NOT_YET_RECRUITINGGuangzhou, Guangdong, 510080, China
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Guy's Hospital - Guy's & St. Thomas NHS Foundation Trust
NOT_YET_RECRUITINGSouthwark, London, DE1 9RT, United Kingdom
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Hagaziekenhuis
NOT_YET_RECRUITINGThe Hague, South Holland, 2545AA, Netherlands
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Hematology Ohta Clinic,Shinsaibashi
RECRUITINGOsaka, Osaka, 542-0081, Japan
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Henan Cancer Hospital
RECRUITINGZhengzhou, Henan, 450004, China
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Hospital General Universitario Gregorio Maranon
NOT_YET_RECRUITINGMadrid, Mardrid, 28007, Spain
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Hospital Universitario 12 de Octubre
NOT_YET_RECRUITINGMadrid, Mardrid, 28041, Spain
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Hospital Universitario De Salaman
NOT_YET_RECRUITINGSalamanca, 37007, Spain
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Hospital Universitario Fundacion Alcorcon
NOT_YET_RECRUITINGAlcorcón, Mardrid, 28922, Spain
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Hospital Universitario Virgen del Rocio
RECRUITINGSeville, 41013, Spain
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IN-VIVO sp. z o.o.
WITHDRAWNBydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-048, Poland
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Imperial College Healthcare NHS Trust
RECRUITINGLondon, W12 0HS, United Kingdom
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Innovative Hematology, Inc.
NOT_YET_RECRUITINGIndianapolis, Indiana, 46260, United States
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Institute of Hematology and Blood Diseases Hospital Chinese Academy of Medical Sciences - PPDS
RECRUITINGTianjin, Tianjin Municipality, 300020, China
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Instytut Hematologii i Transfuzjologii Klinika Zaburzen Hemostazy i Chorob Wewnetrznych
NOT_YET_RECRUITINGWarsaw, Masovian Voivodeship, 02-776, Poland
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Jinshan Hospital of Fudan University
RECRUITINGShanghai, Shanghai Municipality, 201508, China
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Kansai Medical University Hospital
RECRUITINGHirakata-shi, Osaka, 573-1191, Japan
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Korea University Anam Hospital
RECRUITINGSeoul, 2841, South Korea
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Kyungpook National University Hospital
NOT_YET_RECRUITINGDaegu, 41944, South Korea
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Leeds Teaching Hospitals NHS Trust
RECRUITINGLeeds, Yorkshire, LS9 TF, United Kingdom
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Lewis Katz School of Medicine at Temple University
NOT_YET_RECRUITINGPhiladelphia, Pennsylvania, 19140, United States
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
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Medical Center "Fama Medical"
RECRUITINGPlovdiv, 4002, Bulgaria
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MidAmerica Cancer Center
NOT_YET_RECRUITINGKansas City, Missouri, 64132, United States
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Military Medical Academy Multiprofile Hospital for Active Treatment - Sofia
RECRUITINGSofia, Sofia-Grad, 1606, Bulgaria
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Monash University - Australian Centre for Blood Diseases (ACBD)
RECRUITINGMelbourne, Victoria, 3004, Australia
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N. Copernicus Provincial MCOT in Lodz
NOT_YET_RECRUITINGLodz, Łódź Voivodeship, 93-513, Poland
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National Hospital Organization Mito Medical Center
NOT_YET_RECRUITINGIbaraki, 311-3193, Japan
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Nihon University Itabashi Hospital
RECRUITINGItabashi-ku, Tokyo, 173-8610, Japan
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Olympion General Clinic & Rehabilitation Center
NOT_YET_RECRUITINGPátrai, 264 43, Greece
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Oregon Health & Science University
RECRUITINGPortland, Oregon, 97239, United States
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Osaka University Hospital
RECRUITINGSuita-shi, Osaka, 565-0871, Japan
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Peking Union Medical College Hospital
RECRUITINGBeijing, Beijing Municipality, 100730, China
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Perelman Center for Advanced Medicine (PCAM) Hospital of The University of Pennsylvania Penn Blood Disorders Program
NOT_YET_RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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Perth Blood Institute
RECRUITINGWest Perth, Western Australia, 6005, Australia
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Peter MacCallum Cancer Centre
NOT_YET_RECRUITINGMelbourne, Victoria, 3000, Australia
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Pratia Onkologia Katowice - PRATIA
NOT_YET_RECRUITINGKatowice, Silesian Voivodeship, 40-523, Poland
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Qilu Hospital of Shandong University
RECRUITINGJinan, Shandong, 250012, China
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Queen Mary Hospital
RECRUITINGHong Kong, Pok Fu Lam, Hong Kong
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Rocky Mountain Cancer Center
WITHDRAWNDenver, Colorado, 80218, United States
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Royal Liverpool and Broadgreen University Hospitals NHS Trust
NOT_YET_RECRUITINGLiverpool, Merseyside, L7 8XP, United Kingdom
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Saitama Medical University Hospital
RECRUITINGIruma-gun, Saitama, 350-0495, Japan
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Sakarya University Education and Research Hospital
NOT_YET_RECRUITINGSakarya, 54290, Turkey (Türkiye)
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Samsung Medical Center
RECRUITINGSeoul, 06351, South Korea
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Seoul National University Bundang Hospital
RECRUITINGSeongnam-si, Gyeonggi-do, 13620, South Korea
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Seoul National University Hospital (SNUH)
NOT_YET_RECRUITINGSeoul, 03080, South Korea
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Severance Hospital, Yonsei University Health System
RECRUITINGSeoul, 03722, South Korea
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Shaanxi Provincial People's Hospital
NOT_YET_RECRUITINGXi'an, Shaanxi, 710068, China
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Shengjing Hospital of China Medical University - Nanhu Campus
NOT_YET_RECRUITINGShenyang, Liaoning, 110004, China
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Southampton General Hospital
RECRUITINGSouthampton, Hampshire, SO16 6YD, United Kingdom
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St George Hospital
RECRUITINGKogarah, New South Wales, 2217, Australia
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The Alfred Hospital
RECRUITINGMelbourne, Victoria, 3005, Australia
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The First Affiliated Hospital of Guangxi Medical University
RECRUITINGNanning, Guangxi, 530021, China
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The First Affiliated Hospital of Nanchang University - Donghu Campus
RECRUITINGNanchang, Jiangxi, 330006, China
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The First Affiliated Hospital of Soochow University - Shizijie Campus
NOT_YET_RECRUITINGSuzhou, Jiangsu, 215006, China
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The First Hospital of Hebei Medical University
RECRUITINGShijiazhuang, Hebei, 050031, China
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The Second Affiliated Hospital of Kunming Medical University
RECRUITINGKunming, Yunnan, 650101, China
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The University of Iowa
NOT_YET_RECRUITINGIowa City, Iowa, 52242, United States
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The University of Tokyo Hospital
RECRUITINGBunkyo-ku, Tokyo, 113-8655, Japan
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Tohoku University Hospital
RECRUITINGSendai, Miyagi, 980-8574, Japan
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Tokyo Metropolitan Bokutoh Hospital
RECRUITINGSumida-ku, Tokyo, 130-0022, Japan
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Trakya Universitesi Tip Fakultesi Hastanesi
NOT_YET_RECRUITINGEdirne, 22030, Turkey (Türkiye)
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UMHAT SofiaMed, OOD
RECRUITINGSofia, 1750, Bulgaria
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UMHAT Sv. Ivan Rilski
RECRUITINGSofia, 1431, Bulgaria
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USC Norris Comprehensive Cancer Center - Keck Medicine of USC
NOT_YET_RECRUITINGLos Angeles, California, 90033, United States
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Union Hospital Tongji Medical College Huazhong University of Science and Technology
RECRUITINGWuhan, Hebei, 430022, China
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Universita degli Studi di Roma La Sapienza - Umberto I Policlinico di Roma
NOT_YET_RECRUITINGRome, Lazio, oo610, Italy
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University College London Hospitals
NOT_YET_RECRUITINGLondon, NW1 2PG, United Kingdom
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University Hospitals of Leicester NHS Trust
RECRUITINGLeicester, East Midlands, LE1 5WW, United Kingdom
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University Hospitals of North Midlands NHS Trust, Royal Stoke University Hospital
RECRUITINGStoke-on-Trent, Staffordshire, ST4 6QG, United Kingdom
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University Multiprofile Hospital for Active Treatment - Prof. Dr. Stoyan Kirkovich AD
NOT_YET_RECRUITINGStara Zagora, 6003, Bulgaria
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University Of Louisville Brown Cancer Center
NOT_YET_RECRUITINGLouisville, Kentucky, 40202, United States
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University of Massachusetts Chan Medical School
NOT_YET_RECRUITINGWorcester, Massachusetts, 01655, United States
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University of New South Wales (UNSW) - Liverpool Hospital - Liverpool Cancer Therapy Centre
RECRUITINGLiverpool, New South Wales, 2170, Australia
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University of Washingto
NOT_YET_RECRUITINGSeattle, Washington, 98109, United States
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Versiti Wisconsin, Inc
NOT_YET_RECRUITINGMilwaukee, Wisconsin, 53226, United States
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Virginia Oncology Associates
NOT_YET_RECRUITINGNorfolk, Virginia, 23502, United States
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West China Hospital Sichuan University
RECRUITINGChengdu, Sichuan, 610041, China
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Westmead Hospital
RECRUITINGWestmead, New South Wales, 2145, Australia
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Yamanashi Prefectural Central Hospital
RECRUITINGKofu, Yamanashi, 400-8506, Japan
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Yokohama City University Medical Center
NOT_YET_RECRUITINGYokohama, Kanagawa, 232-0024, Japan
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Zhejiang Provincial Hospital of Chinese Medicine - Main
NOT_YET_RECRUITINGHangzhou, Zhejiang, 310006, China
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