Gene therapy breakthrough targets kidney disease in High-Risk patients
NCT ID NCT07182227
First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times
Summary
This study tests a new gene therapy, PS-002, for adults with IgA nephropathy, a kidney disease that can lead to kidney failure. The therapy aims to control the disease in people who are at high risk of getting worse despite current treatments. Participants receive a single dose and are monitored for up to 5 years to check safety and how well it works.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cardiff and Vale University Health Board
NOT_YET_RECRUITINGCardiff, CF14 4XW, United Kingdom
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Leicester General Hospital
NOT_YET_RECRUITINGLeicester, Leicestershire, LE5 4PW, United Kingdom
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Manchester University NHS Foundation Trust
RECRUITINGManchester, Greater Manchester, M13 9WL, United Kingdom
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Nottingham University Hospitals NHS Trust
RECRUITINGNottingham, Nottinghamshire, NG5 1PB, United Kingdom
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Royal Infirmary of Edinburgh Clinical Research Facility
RECRUITINGEdinburgh, EH16 4SA, United Kingdom
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Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust
RECRUITINGManchester, Greater Manchester, M13 9WL, United Kingdom
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Southmead Hospital
RECRUITINGBristol, BS10 5NB, United Kingdom
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The Johns Hopkins Hospital
RECRUITINGBaltimore, Maryland, 21287, United States
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The Royal London Hospital
RECRUITINGLondon, E1 1FR, United Kingdom
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University of Miami Hospital
RECRUITINGMiami, Florida, 33136, United States