Pig cell transplant trial aims to stop severe low blood sugar in type 1 diabetes

This early-phase study tests a new treatment called OPF-310, which uses pig islet cells enclosed in a protective capsule, for people with unstable type 1 diabetes who still experience severe low blood sugar episodes despite using an automated insulin pump and continuous glucose monitor. The main goal is to see if the transplant is safe and can help control blood sugar without causing dangerous lows. About 13 adults aged 35 to 65 will receive an ascending dose of the cells and be monitored for a year.