Pig cell transplant trial aims to stop severe low blood sugar in type 1 diabetes

NCT ID NCT06575426

First seen Nov 01, 2025 · Last updated Jun 10, 2026 · Updated 27 times

Summary

This early-phase study tests a new treatment called OPF-310, which uses pig islet cells enclosed in a protective capsule, for people with unstable type 1 diabetes who still experience severe low blood sugar episodes despite using an automated insulin pump and continuous glucose monitor. The main goal is to see if the transplant is safe and can help control blood sugar without causing dangerous lows. About 13 adults aged 35 to 65 will receive an ascending dose of the cells and be monitored for a year.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for TYPE 1 DIABETES are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Illinois Hospital & Health Sciences System

    RECRUITING

    Chicago, Illinois, 60612, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

autoimmune disease diabetes mellitus glucose metabolism disease hypoglycemia immune system disorder metabolic disease type 1 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.