Pig cell transplant trial aims to end severe lows in type 1 diabetes

NCT ID NCT06575426

First seen Nov 01, 2025 · Last updated May 06, 2026 · Updated 19 times

Summary

This early-stage study tests a new treatment called OPF-310, which uses pig islet cells enclosed in a protective capsule, for people with unstable type 1 diabetes who still experience dangerous low blood sugar episodes despite using an automated insulin pump and continuous glucose monitor. The goal is to see if the transplanted cells can safely help control blood sugar and eliminate severe hypoglycemic events. The study involves 13 adults aged 35-65 and will test increasing doses of the cell product.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Illinois Hospital & Health Sciences System

    RECRUITING

    Chicago, Illinois, 60612, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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