New bone marrow transplant could help kids with sickle cell and immune disorders

NCT ID NCT03128996

First seen Jan 07, 2026 · Last updated May 07, 2026 · Updated 11 times

Summary

This study tests a bone marrow transplant from a partially matched family donor for children under 21 with severe non-cancer diseases like sickle cell disease, bone marrow failure, or immune disorders. The goal is to see if the transplant can control the disease with fewer side effects. Participants receive a milder conditioning regimen before the transplant to reduce risks.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Helen DeVos Children's Hospital

    RECRUITING

    Grand Rapids, Michigan, 49503, United States

    Contact

    Contact

  • Nemours Children's Health

    RECRUITING

    Wilmington, Delaware, 19803, United States

    Contact Phone: •••-•••-••••

    Contact

  • Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Yale School of Medicine

    RECRUITING

    New Haven, Connecticut, 06510, United States

    Contact

    Contact

Conditions

Explore the condition pages connected to this study.