Ancient herb takes on PCOS: new hope for millions?

NCT ID NCT07603505

Completed Disease control Sponsor: Jinnah Sindh Medical University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a herbal extract from a Himalayan plant (Nepeta adenophyta) in 116 women with PCOS. Participants took either the herb, the standard drug metformin, or both for 4 months. The goal was to see if the herb could help restore regular menstrual cycles and improve metabolic health. This is an early-stage trial, so results are preliminary but could point to a new treatment option.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Nepeta adenophyta hedge extract (NAE)
What this could lead to: If it works, this could offer a new, natural option for managing PCOS symptoms like irregular periods and insulin resistance, possibly with fewer side effects than current drugs.
What could go wrong: This is an early Phase 1 trial, so results are preliminary. The herb may not work better than existing treatments, and its long-term safety is unknown. Side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

infertility disorder Insulin Resistance metabolic disease polycystic ovary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INFERTILITY METABOLIC DISORDERS POLYCYSTIC OVARIAN SYNDROME (PCOS)

Contacts and locations

Locations

Jinnah Postgraduate Medical Centre

Karachi, Sindh, Pakistan

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