SURGERY

This study tested whether briefly stopping blood flow to the aorta before surgery (called ischemic pre-conditioning) could reduce complications in people undergoing open repair of a thoracoabdominal aortic aneurysm. 65 patients were randomly assigned to receive either the pre-con…

This completed study looked at whether giving chemotherapy before surgery (neoadjuvant chemo) helps people with resectable pancreatic cancer live longer compared to having surgery right away. Thirty patients took part. The main goal was to see which approach leads to better overa…

This pilot study tested a goal-directed therapy system that uses a special monitor and algorithm to predict low blood pressure in 100 adults after heart surgery. The device helped guide doctors on when to give fluids or medications to keep blood pressure stable. The goal was to s…

This study tested whether adding stabilization exercises to standard physical therapy helps people recover better after cervical laminoplasty surgery. Thirty-two patients were split into two groups: one did standard exercises, the other added stabilization moves using a pressure …

This pilot study tested whether giving a mix of glucose, insulin, and potassium (GIK) during abdominal surgery can reduce serious complications in patients who do not have diabetes. About 106 adults took part to see if the treatment is practical and safe. The goal is to plan a la…

This large international trial tested whether keeping a patient's blood flow (cardiac index) at their own personal baseline during major abdominal surgery reduces serious complications. Over 1,100 high-risk adults aged 45 and older took part. The goal was to see if this personali…

This study compared two common surgeries for fixing a broken kneecap: tension band wiring and locking plate fixation. Researchers randomly assigned 122 adults to one of the two procedures and tracked their recovery using a knee function score. The goal was to see which method lea…

This study looked at whether adding dexmedetomidine to standard morphine pain relief after cancer surgery helps elderly patients (65-90 years) live longer. 1,500 participants were randomly assigned to receive either morphine alone or morphine plus dexmedetomidine for three days a…

This study tested a vacuum-assisted closure device (Prevena) on the surgical wounds of 104 adults who had spinal fusion surgery. The goal was to see if the device could reduce problems like infections, wound reopening, and fluid buildup under the skin. Researchers also tracked sk…

This study tested whether applying vancomycin powder directly to the surgical wound during brain surgery can reduce infections. Over 1,100 adults having neurosurgery were randomly assigned to receive either the topical vancomycin or standard care. The main goal was to see if the …

This study tested whether using a mask that helps with breathing (non-invasive ventilation) can prevent the need for a breathing tube in patients who develop respiratory failure after abdominal surgery. 300 adults who had abdominal surgery and then had trouble breathing were rand…

This study tested whether the Oxiris membrane, a filter used during heart-lung machine support, can reduce inflammation and improve blood flow in small blood vessels after heart surgery. 70 adults having elective heart surgery with a long bypass time took part. The membrane aims …

This study tests whether a new pulse contour device can accurately detect increases in stroke volume during a fluid challenge in patients undergoing high-risk abdominal surgery. Researchers will compare the device's readings to those from transthoracic echocardiography. The goal …

This trial tested a dye called bevonescein that makes nerves glow under special light during surgery. 154 people having head or neck surgery received the dye before their operation. Surgeons then compared standard white light with the glowing view to see if nerves were easier to …

This study tested whether a heart ultrasound measure called the superior vena cava collapsibility index (SVC-CI) can predict which patients need fluids during major abdominal or aortic surgery. Researchers gave 150 patients a small fluid bolus and measured heart output changes. T…

This study explored whether breast cancer has a unique smell that can be detected. Researchers used a special polymer (Sorbstar®) and trained dogs to sniff samples from 35 women before and after tumor removal. The goal was to see if a distinct scent signature exists, which could …

This study looked at whether teaching women simple self-massage and stretching exercises before and after breast cancer surgery could prevent long-term pain. 143 women took part. Half received standard care, and the other half also attended workshops to learn these techniques and…

This trial investigates whether a double-reading animated film, watched by both children and their parents before surgery, can reduce anxiety in children aged 3 to 7. The film uses avatars to walk the child through their hospital journey, from room to operating room. Researchers …

This study tested whether a 4-week home exercise program, guided by a wearable fitness device and supervised remotely, could help lung cancer patients get in better shape before surgery. Thirty people with early-stage non-small cell lung cancer participated. The goal was to see i…

This study tested if a local pain injection (liposomal bupivacaine) works as well as an epidural for pain relief after open gynecologic surgery. 106 adults participated. The goal was to see if the injection could provide similar pain control and recovery while being more cost-eff…

This study tested a digital game called PeroPap designed to prepare children aged 7-10 and their parents for day surgery. The game teaches kids about the operation through a cartoon story and a song, and includes a parent module with information. Researchers measured children's a…

This study tested whether a drug called sugammadex helps people wake up faster after heart surgery. 74 adults having heart surgery with a heart-lung machine received either sugammadex or a placebo. The main goal was to see if more patients could have their breathing tube removed …

This study tested whether doing Kegel pelvic floor exercises in the first 8 hours after lumbar disc surgery helps with urinary retention, pain, and comfort. 58 adults who had back surgery under general anesthesia and could not move for 8 hours after surgery took part. The exercis…

This study looked at whether doing special exercises before colorectal cancer surgery (called prehabilitation) helps patients recover better compared to standard care. Over 700 adults scheduled for surgery took part. The main goal was to see if the exercise group had better physi…

This completed study tested whether progressive relaxation exercises could help patients sleep better after urological surgery. Two adults aged 18 or older, with no sleep disorders, practiced tensing and relaxing muscles while focusing on breathing. The goal was to see if this si…

This study tested whether soaking feet in warm water for 20 minutes before pituitary tumor surgery helps patients feel less anxious and keeps vital signs stable. 100 adults were enrolled, with one group receiving the foot bath and the other standard care. Researchers measured anx…

This study compared two ways to control pain after minimally invasive heart bypass surgery: a newer erector spinae plane block (ESPB) versus the standard paravertebral block (PVB). 140 patients received one of the two blocks using the numbing drug ropivacaine. The goal was to see…

This study tested whether giving EXACYL before surgery can reduce bleeding during and after jaw realignment surgery. 157 adults took part in a double-blind, placebo-controlled Phase 3 trial. The goal was to see if the drug makes surgery safer and more comfortable.

This early-phase trial tested whether a nutritional supplement called Impact Advanced Recovery® could help men recover better after bladder cancer surgery. Thirty men took the drink before and after their operation. The goal was to see if it reduced surgical complications, infect…

This study looked at whether walking to the operating room instead of being taken on a stretcher can lower anxiety before surgery. Over 1,200 adults having different types of surgery took part. Researchers measured anxiety using a standard questionnaire. The goal was to see if th…

This study tested a less invasive spine surgery in one person with neuromuscular scoliosis, a severe spine curve caused by nerve or muscle problems. The goal was to see if the mini-invasive approach could reduce pain, blood loss, and complications compared to standard surgery. Th…

This study tested whether watching short comedy films after Uretero-Renoscopy (URS) surgery could lower pain and anxiety. 110 adult patients were shown 10-minute Turkish comedy videos. Researchers measured pain and anxiety levels to see if laughter helped recovery. The goal is to…

This study tested a gel called PuraSinus to see if it makes follow-up cleanings after sinus surgery less painful. 30 adults with chronic sinus disease took part. The gel was compared to standard nasal dressings. The goal was to reduce pain and discomfort during these cleanings.

This study tested whether playing local music to patients after laparoscopic abdominal surgery can reduce pain and improve comfort. 120 adults in Turkey and Iran took part. Researchers measured pain using a number scale and comfort with a questionnaire. The goal is to see if a si…

This study tested a shorter course of radiation therapy for people with early-stage breast cancer after lumpectomy. The goal was to see if this approach causes fewer skin side effects. 35 participants received the treatment, and researchers measured how many developed moderate to…

This study looked at how well custom-made implants work for people having jaw surgery (orthognathic surgery). 56 patients received personalized guides and plates during their operation. The main goal was to see if these implants improved patients' quality of life after surgery.

This study looked at whether adding dexmedetomidine to standard morphine pain relief after cancer surgery could lower the chance of delirium (sudden confusion) in patients aged 65 and older. A total of 1500 participants were randomly assigned to receive either morphine alone or m…

This study looked at whether listening to music for a week before colon cancer surgery can lower anxiety. 116 adults scheduled for surgery were asked to listen to music three times a day. Their anxiety levels were compared to a group that did not have a music routine. The goal is…

This study looked at whether teaching patients about pain before a planned hysterectomy (removal of the uterus) could help lower their anxiety, stress, and pain after surgery. 62 adults took part and received either standard care or extra education about pain. The goal was to see…

This study tested whether letting patients pick their own aromatherapy scent (lavender, geranium, lemongrass, or sandalwood) could lower anxiety before eye surgery. 64 adults undergoing short eye procedures chose their preferred scent or received an odorless placebo patch. Resear…

This study tested a set of care steps called Enhanced Recovery After Surgery (ERAS) in 82 children who had their appendix removed. The steps included teaching families what to expect, avoiding tubes, and helping kids eat and move early after surgery. The goal was to see if this p…

This study tested Emotional Freedom Techniques (EFT), a type of tapping therapy, on 53 pregnant women scheduled for a planned C-section. The goal was to see if EFT could reduce their anxiety, fear of surgery, and feelings of traumatic birth. The therapy is non-invasive, inexpensi…

This study tested whether adding blood flow restriction (BFR) training to standard physical therapy helps military cadets recover shoulder strength and function after stabilization surgery. Forty cadets were split into two groups: one received BFR plus therapy, the other therapy …

This study tested whether a virtual reality game called ReCognitionVR could help older adults (60+) stay mentally alert after abdominal surgery. Thirty participants used the VR headset or standard orientation methods. The goal was to see if the VR approach is safe, acceptable, an…

This study tested whether a biofeedback-based virtual reality (VR) program could help children and teens aged 12-18 manage pain after surgery. 93 participants used the VR tool before and after their operation. The goal was to see if the approach was feasible and acceptable, not y…

This study tested whether interactive physical therapy (using computer-based balance and strength exercises) could help frail older adults recover better after open heart surgery. 153 participants aged 65 and older were assigned to either multicomponent training or computer-based…

This study investigates whether using lower pressure on the lungs (PEEP) along with extra fluids can prevent blood pressure drops in patients undergoing spine surgery in the knee-chest position. The knee-chest position naturally lowers blood pressure, and standard protective lung…

This study observed 30 elderly patients (over 65) who had a specific type of neck fracture (odontoid fracture) from a minor fall or low-energy injury. Researchers measured bone density, vitamin D levels, and other bone health markers to understand why these fractures happen. They…

This study looked at whether a personalized breathing method during chest surgery could lower the chance of lung problems afterward in children under 5. Sixty-three kids having chest surgery were split into two groups: one got the standard breathing settings, the other got settin…

This study looked at 250 adults with heart stents who were taking blood thinners and needed non-cardiac surgery. Researchers used special blood tests to measure how well the blood was thinned and tracked whether patients had serious heart problems after surgery. The goal was to s…

This study tested a new way to monitor vision during brain surgery near the optic nerve. Researchers used special goggles and anesthesia to track brain signals (visual evoked potentials) in 40 patients. The goal was to see if this method could help surgeons avoid damaging eyesigh…

This study looked at how a device called TetraGraph can help doctors measure muscle relaxation in children during surgery. The goal was to find the right amount of a muscle relaxant drug (rocuronium) needed to keep the patient still but safe. Fifty children under 18 took part, an…

This completed study tested a new device called the TetraGraph, which measures muscle recovery during surgery using electrical signals, in 50 infants under 1 year old. The goal was to see if it works better than the standard visual check doctors use. If accurate, it could help do…

This study tested whether a pulse oximeter placed in the throat (oropharynx) can accurately measure blood oxygen levels during surgery. Researchers compared readings from the throat sensor to standard finger or toe sensors and to blood tests. The goal was to see if this new appro…

This study tracked 295 adults who had high-risk surgery for stomach, esophagus, pancreas, or liver cancer. Researchers measured quality of life before surgery and again at 6 and 12 months after. They also asked patients and their family members if they regretted the decision to h…

This study looked at whether a surgery called STARR, used to treat severe constipation caused by a rectocele or intussusception, affects the anal sphincter's ability to stretch and hold. Nine patients were tested before and 3 months after surgery using a special balloon device (E…

This study tested a non-invasive device that measures muscle activity to see how well nerve blocks work during surgery in children under 5. The device uses sticky patches on the skin to track the effects of spinal or caudal anesthesia. Researchers also looked at how a common addi…

This study looked at whether certain substances in the blood (decorin and TGF β1) can predict the presence and severity of internal scar tissue (adhesions) before abdominal surgery. Researchers studied 56 women with a history of prior abdominal surgery who were scheduled for a gy…

This study tested whether free, open-source software can create 3D models of the lungs to help surgeons during lung cancer surgery. 13 patients scheduled for lung surgery had their CT scans turned into 3D reconstructions. The goal was to see if these models were easy for surgeons…

This completed study looked at 204 patients who had a kidney removed (nephrectomy) to find out what factors might lead to chronic pain lasting months or years after surgery. Researchers measured pain levels at 1 hour, 3 months, and 1 year after the operation using a simple 0-to-1…

This study tested a wearable monitoring system that tracks vital signs like heart rate and breathing continuously. The goal was to see if it helps hospital staff detect when surgical patients are getting worse faster than standard checks. 240 adults on a surgical ward took part, …

This study looked at how doctors in the U.S. manage blood thinners in heart patients who need surgery. The goal was to understand the risks of bleeding and clotting with different approaches. 147 patients were observed to gather data for future research. No new treatments were te…

This study used artificial intelligence to learn the patterns of reduced blood flow to the brain during planned surgeries. 60 patients having carotid artery surgery or stroke clot removal were monitored with non-invasive devices. The goal was to teach AI to recognize these patter…

This study looked back at 765 children with complicated appendicitis treated over ten years. Researchers wanted to see how well laparoscopic surgery works for different types of the condition, including cases with abscess or mass. The goal is to help doctors decide the best treat…

This completed study from Tunisia looked at 120 people with high blood pressure who were scheduled for minor abdominal surgery. Researchers checked their blood pressure on the day of surgery and noted how often it was high enough to cancel the procedure. They also measured anxiet…

This completed study tracked 132 children with obstructive sleep apnea who had their tonsils removed. Researchers recorded how many had breathing problems after surgery, especially those with other health issues. The goal was to create a simple flowchart to help doctors decide wh…

This study looked at 16 people with severe facial paralysis to see how their brains change after reconstructive surgery. Using a brain scanning technique called magnetoencephalography (MEG), researchers measured brain activity during facial movements and while recognizing emotion…

This study reviewed records of 610 older adults (over 65) on blood thinners who had hip fracture surgery. Researchers wanted to see how long surgery was delayed to avoid bleeding risks and whether that delay affected survival. The goal is to find the safest approach to schedule s…

This study tested a new portable device called MARIE that measures carbon dioxide (CO2) in the breath of 40 adults after surgery. The goal was to see if MARIE works as well as standard hospital monitors for detecting breathing problems early. Researchers compared MARIE's readings…

This small, completed study looked at how many Hydrus microstent surgeries glaucoma fellows need to perform before they become skilled. Researchers graded videos of surgeries from 5 fellows at three eye centers. The goal was to find the average number of cases needed to reach an …

This study looked at 320 adults who had heart surgery to see how well two different risk scores (EuroSCORE-II and POSPOM) predict the chance of dying in the hospital. Researchers calculated each patient's scores before surgery and compared them to what actually happened. The goal…

This study tested a device called SMART ANGEL that lets patients record their blood pressure, heart rate, and oxygen levels at home after outpatient surgery. 30 adults used the device to send their health data to doctors. The goal was to see if the device is easy to use and works…

This pilot study looked at whether the COVID-19 virus can spread through the air during surgery on infected patients. Researchers took air samples and swabbed surfaces in the operating room during two surgeries. The goal was to understand contamination risks so that healthcare wo…

This study tested whether having spine surgery patients wear an Apple Watch could help doctors track their recovery. 255 adults wore the watch before and after surgery to measure steps and distance. The goal was to see if this data matched how patients felt and if it could improv…

This study looked at over 3,600 adults having major surgery to find out which of two blood pressure drugs (norepinephrine or phenylephrine) works best to prevent complications like kidney injury or death. Patients received one of the two drugs during their operation. The goal was…

This study looked at how often a nerve block for shoulder surgery causes temporary paralysis of the diaphragm, the main breathing muscle. Researchers compared two ways of giving the block to 84 patients. The goal was to see which approach is safer for people with breathing proble…

This study looked at whether follow-up visits after sports medicine surgery can be done by phone instead of in person. 90 patients were randomly assigned to virtual phone visits or in-person visits at 6 weeks, 12 weeks, and 6 months after surgery. Researchers measured patient sat…

This study tested whether a 6-week online exercise program (PreActiv) is practical for patients waiting for major surgery. 35 participants did three 35-minute home workouts each week, including cardio and strength exercises. The goal was to see how many people stuck with the prog…

This study tested a communication tool designed to help adults who are about to have fecal ostomy surgery. Researchers wanted to see if patients and their clinicians found the tool acceptable and easy to use. About 25 patients and 4 clinicians took part, with at least half of the…

This study tested a device called ANI that measures pain during weight-loss surgery in 15 adults. The goal was to see if using the monitor helps doctors give less morphine. The study is complete and focused on improving pain control during surgery.

This completed study looked at how the body digests and uses food during weight loss from bariatric surgery. Researchers used advanced 'omics' techniques to track nutrients in 7 participants. The goal was to understand why weight loss varies between people and to generate ideas f…

This study looked at 605 patients with esophageal cancer who had minimally invasive surgery to remove their esophagus. Researchers compared those with and without type 2 diabetes to see if diabetes affected short-term complications and long-term survival. The goal is to understan…

This study involved 89 patients with distal sigmoid or rectal cancer who underwent standard surgery with high ligation of the inferior mesenteric artery. Researchers used CT scans before and after surgery to map blood flow paths and check if their planned routes matched reality. …

This study tested whether lung ultrasound can help doctors give the right amount of fluid during surgery. 200 adults having various surgeries were monitored with both lung ultrasound and an esophageal Doppler. The goal was to see if a change in ultrasound pattern (from A to B lin…

This study tested a wearable, non-invasive blood pressure monitor called ViTrack against the standard method of placing a small tube in the wrist artery. Researchers compared blood pressure readings from 30 surgery or ICU patients at 255 time points. The goal was to see if the cu…

This pilot study tested whether adding ergonomics training to the surgical curriculum helps OB/GYN residents learn safer body movements to prevent work-related injuries. 23 residents took a class on ergonomics and then practiced surgical skills on a model. Half received personali…

This completed study from a French hospital center surveyed 143 patients who had phalloplasty surgery between 2007 and 2018. Researchers collected data on surgical results, sexual quality of life, and patient satisfaction using questionnaires and medical records. The goal is to b…

This pilot study tested whether keeping blood pressure within a range that ensures good blood flow to the brain during surgery is feasible and safe compared to usual care. Researchers enrolled 27 older adults having hip, knee, or lung surgery. They measured how often blood pressu…