New filter may protect tiny blood vessels during heart surgery

NCT ID NCT04201119

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested whether the Oxiris membrane, a filter used during heart-lung machine support, can reduce inflammation and improve blood flow in small blood vessels after heart surgery. 70 adults having elective heart surgery with a long bypass time took part. The membrane aims to remove inflammatory substances from the blood, potentially preventing microcirculation problems that often occur after such operations.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Oxiris membrane (a device used during heart-lung machine to filter inflammatory substances from the blood)

What this could lead to

If it works, this could point toward a way to reduce complications after heart surgery by improving blood flow in tiny vessels.

What could go wrong

This is a small pilot study with only 70 people, so results may not apply widely. The membrane is used only during surgery, and long-term benefits are uncertain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Amiens-Picardie

    Amiens, 80054, France