Chill out: cooling spray may ease needle pain in skin cancer surgery

NCT ID NCT06920381

First seen Jun 26, 2026 · Last updated Jul 07, 2026 · Updated 2 times

Summary

This study tests whether spraying a cooling mist (ethyl chloride) on the skin before a numbing injection can reduce pain during Mohs surgery for skin cancer. Eighty adults will have half their surgical site pre-cooled and the other half not, then rate their pain. The goal is to find a simple way to ease needle fear and discomfort.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ethyl chloride spray
What this could lead to
If it works, this could offer a simple, quick way to reduce needle pain and anxiety during Mohs surgery.
What could go wrong
This is a very early, small trial (80 people) testing a short-term effect. The pain reduction may be minimal or not noticeable, and results may not apply to other procedures.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UC Davis Dermatology

    Sacramento, California, 95816, United States

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