Chill out: cooling spray may ease needle pain in skin cancer surgery

NCT ID NCT06920381

Recruiting now Symptom relief Sponsor: University of California, Davis Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether spraying a cooling mist (ethyl chloride) on the skin before a numbing injection can reduce pain during Mohs surgery for skin cancer. Eighty adults will have half their surgical site pre-cooled and the other half not, then rate their pain. The goal is to find a simple way to ease needle fear and discomfort.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ethyl chloride spray

What this could lead to

If it works, this could offer a simple, quick way to reduce needle pain and anxiety during Mohs surgery.

What could go wrong

This is a very early, small trial (80 people) testing a short-term effect. The pain reduction may be minimal or not noticeable, and results may not apply to other procedures.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SURGERY

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

UC Davis Dermatology
RECRUITING

Sacramento, California, 95816, United States

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