SURGERY

This study is testing a new bone graft material called Induce XT in people having surgery to fuse bones in their foot or ankle. The graft is designed to fill gaps and help the bones grow together. Researchers will follow 60 patients for one year after surgery, using X-rays and qu…

This study aims to find the better way to surgically treat peri-implantitis, a condition where bone deteriorates around a dental implant. It will compare two methods in 52 patients: placing a bone graft material alone versus placing the same graft covered with a resorbable collag…

This study is testing whether giving the drug lorlatinib before surgery or radiation helps people with stage III non-small cell lung cancer that has a specific genetic change (ALK fusion). About 48 participants will take lorlatinib for three cycles. Doctors will then check if the…

This study aimed to see if a 4-day low-calorie, low-protein 'shake' diet before leg bypass surgery could help prevent vein grafts from failing. Researchers wanted to test if patients could follow this diet at home and if it boosted the body's natural production of hydrogen sulfid…

This study is testing if using a bedside lung ultrasound during surgery can help doctors better adjust a breathing machine's pressure settings. The goal is to see if this personalized approach helps keep the lungs open and healthy in patients having robotic surgery for prostate o…

This pilot study is testing whether allowing slightly lower blood pressure after heart surgery is safe and beneficial. It will compare two groups: one where blood pressure is kept just above 60 mmHg and another receiving standard care. The goal is to see if this approach reduces …

This study is testing a structured plan for delivering nutrition to patients in the intensive care unit (ICU) after major abdominal surgery or trauma. The goal is to see if this careful feeding approach, which uses a device to measure calorie needs and includes tube feeding and s…

This study compares two different types of stomach surgery for people with severe obesity. Researchers want to see which procedure leads to better weight loss and improvement in health problems like diabetes and high blood pressure, while also checking which one causes fewer nutr…

This study is testing whether a program of brain-training computer games and guided physical exercise, done before and after major surgery, can help older adults protect their thinking skills and ability to live independently. Researchers are comparing this combined program to si…

This large study is testing whether a special air filtration and sterilization system in operating rooms can prevent serious infections and death after surgery. It will involve over 66,000 patients undergoing operations that last at least an hour. The goal is to see if cleaning t…

This study is testing whether giving one of two drugs, mannitol or nitroglycerin, during robotic surgery for prostate or bladder cancer can help prevent a sudden drop in kidney function afterward. It will involve 90 patients with generally healthy or mildly reduced kidney functio…

This study is testing if listening to music helps children feel less pain and fear when they get out of bed for the first time after abdominal surgery. Researchers will compare 74 children aged 4-6; one group will listen to their favorite music during this process, while the othe…

This study is testing whether listening to music before or during hernia surgery helps reduce pain afterwards and decreases the need for strong pain medications. Researchers are enrolling 308 adults having hernia repair to compare different music timing against no music. The goal…

This study is testing whether a simple, independent bedside exercise plan helps older adults recover faster after surgery. Over 2,000 patients aged 65+ having common surgeries will either follow the exercise plan or receive usual hospital care. The goal is to see if getting patie…

This study aimed to see if switching from one common anesthesia drug (isoflurane) to another (desflurane) could help adult surgery patients wake up faster and leave the hospital sooner. The goal was to improve patient flow and potentially reduce costs by shortening recovery time.…

This study is testing if a simple, colorful walkway mat can make it easier for children to get moving after abdominal surgery. Researchers want to see if turning movement into a game reduces kids' pain and fear, and helps them take their first steps sooner. The study involves 74 …

This study aims to understand how two common types of weight-loss surgery affect bone density and strength in teenagers and young adults with severe obesity. Researchers are following 120 participants aged 13-21 for two years, comparing those who have surgery to a similar group w…

This study aimed to check if the breathing machines used during children's surgery deliver the exact amount of air they are programmed to give. Researchers planned to measure the airflow in children aged 0-18 who were having surgery and compare it to the machine's settings. The g…

This study aims to collect healthy and diseased tissue that is normally thrown away after surgeries. Researchers will use these samples to grow cells in the lab and create a library of cell lines. These cells will be used for future research to better understand diseases and deve…

This study aims to understand how the intensive care unit (ICU) environment disrupts patients' natural sleep-wake cycles (circadian rhythms) after heart surgery. Researchers will monitor 15 adult patients' sleep patterns, cognitive function, and how often they're visited by staff…

This study aims to understand why children of different races experience different levels of pain after tonsil removal surgery. Researchers will analyze blood samples from 84 children to look for small chemical differences that might explain this disparity. The goal is to gather …

This study aims to better understand how much muscle relaxant medicine children need during major surgeries. Researchers will use a special monitor to measure muscle responses in patients under 18 years old. The goal is to gather data that could help anesthesiologists use the med…

This study is testing two different ways to train surgeons to communicate more clearly with older patients before surgery. It compares traditional coaching by a specialist against a new automated method that reviews transcripts of doctor-patient conversations. The goal is to see …

This study is testing a new way to measure how well a nerve-block anesthetic is working during surgery. Researchers will place sticker-like sensors on the arms or legs of children and young adults having surgery. The goal is to see if these sensors can provide clear information a…

This study aims to understand and improve the process of checking older adults' overall health before major abdominal surgery. Researchers will observe clinic visits and interview patients, caregivers, and healthcare staff to create a detailed map of the current system. Then, the…