Colon surgery showdown: which operation best relieves chronic constipation?

NCT ID NCT05352074

First seen Apr 30, 2026 · Last updated May 14, 2026 · Updated 3 times

Summary

This study compares two surgical procedures for people with severe, long-term constipation that hasn't improved with other treatments. One surgery removes the entire colon and connects the small intestine to the rectum; the other removes only part of the colon and connects the remaining colon to the rectum. The goal is to see which surgery leads to better bowel function and quality of life. The trial involves 252 adults.

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Contacts and locations

Locations

  • Army Medical Center (Daping Hospital)

    Yuzhong, Chongqing Municipality, 400042, China

  • Chengdu Analrectal Hospital

    Chengdu, Sichuan, 610017, China

  • General Hospital of the Eastern Theater Cammand of the PLA

    Nanjing, Jiangsu, 210002, China

  • No. 940 Hospital of Joint Logistics Support Force of Chinese People's Liberation Army

    Lanzhou, Gansu, 730050, China

  • Qingdao Municipal Hospital

    Qingdao, Shandong, 266011, China

  • Renji Hospital, Shanghai Jiaotong University

    Pudong, Shanghai Municipality, 200127, China

  • Renmin Hospital of Wuhan University

    Wuhan, Hubei, 430060, China

  • Shanghai Pudong New Area People's Hospital

    Pudong, Shanghai Municipality, 201299, China

  • The First Hospital of China Medical University

    Shengyang, Liaoning, 110001, China

  • The General Hospital of Western Theater Command

    Chengdu, Sichuan, 610036, China

  • The Second People's Hospital of Yibin

    Yibin, Sichuan, 644000, China

  • Xijing Hospital

    Xi’an, Shanxi, 710032, China

  • Zhejiang Provincial People's Hospital

    Hangzhou, Zhejiang, 310014, China

  • Zhongnan Hospital of Wuhan University

    Wuhan, Hubei, 430062, China

Conditions

Explore the condition pages connected to this study.