Can a 5-Minute clamp before surgery save lives?

NCT ID NCT03718312

Completed Disease control Sponsor: University Hospital, Rouen Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether briefly stopping blood flow to the aorta before surgery (called ischemic pre-conditioning) could reduce complications in people undergoing open repair of a thoracoabdominal aortic aneurysm. 65 patients were randomly assigned to receive either the pre-conditioning procedure or standard clamping. The main goals were to see if it lowered the chance of serious lung or kidney problems after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ischemic pre-conditioning (brief clamping and release of the aorta before surgery)
What this could lead to: If it works, this could reduce serious lung and kidney complications after major aortic surgery.
What could go wrong: This is a small, completed trial with only 65 participants, so results may not apply to everyone. The procedure itself carries risks during the clamping phase.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

aortic aneurysm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AORTIC ANEURYSM SURGERY

Contacts and locations

Locations

University Hospital, Rouen

Rouen, 76031, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.