Brain-Guided blood pressure during surgery may cut risks

NCT ID NCT05308290

Completed Knowledge-focused Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This pilot study tested whether keeping blood pressure within a range that ensures good blood flow to the brain during surgery is feasible and safe compared to usual care. Researchers enrolled 27 older adults having hip, knee, or lung surgery. They measured how often blood pressure fell outside the brain's comfort zone and checked for complications like heart attack, stroke, and delirium.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this approach could reduce complications like delirium and stroke after surgery in older patients.
What could go wrong: This is a very small pilot study (27 participants) with no phase, so results may not apply broadly. The intervention is a blood pressure management strategy, not a drug, so benefits may be modest.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

delirium hip fracture

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DELIRIUM HIP ARTHROPATHY HIP FRACTURES SURGERY

Contacts and locations

Locations

The Johns Hopkins University

Baltimore, Maryland, 21287, United States

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