Glowing dye could help surgeons avoid cutting nerves
NCT ID NCT05377554
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This trial tested a dye called bevonescein that makes nerves glow under special light during surgery. 154 people having head or neck surgery received the dye before their operation. Surgeons then compared standard white light with the glowing view to see if nerves were easier to spot. The goal is to help surgeons avoid accidentally damaging nerves.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- bevonescein (ALM-488)
- What this could lead to
- If successful, this could give surgeons a real-time way to see nerves during surgery, potentially reducing accidental nerve injury.
- What could go wrong
- This is a completed Phase 3 trial, but results are not yet published. The dye may not improve outcomes enough to change practice, and there may be unknown side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Alume Biosciences
La Jolla, California, 92097, United States
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