Simple blood test may predict hidden surgical risks
NCT ID NCT06639906
First seen Jun 25, 2026 · Last updated Sep 16, 2026 · Updated 3 times
Summary
This study looked at whether certain substances in the blood (decorin and TGF β1) can predict the presence and severity of internal scar tissue (adhesions) before abdominal surgery. Researchers studied 56 women with a history of prior abdominal surgery who were scheduled for a gynecological operation. By comparing blood test results with actual findings during surgery, they hope to develop a non-invasive way to assess adhesion risk.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a simple blood test that helps surgeons know ahead of time if a patient has internal scar tissue, making surgery safer.
- What could go wrong
- This is a small, completed study with only 56 participants. The results may not apply to everyone, and the blood markers may not be reliable enough for routine use.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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56 people
The number who actually took part.
- Started
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Jan 2024
- Finished
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Apr 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with Intraabdominal Adhesions
- Ages
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18 to 50 years
- Sex
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Female participants only
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients who are hospitalized for gynecological reasons with a planned laparotomy or laparoscopic abdominal surgery * Patients with at least 1 previous cesarean section or history of previous abdominal surgery (laparoscopy or laparotomy) Exclusion Criteria: * Patients who do not agree to participate in the study will not be included in the study. * Pregnant patients will not be included in the study (so that the physiological changes of pregnancy do not affect the results) * Presence of preoperative clinical or laboratory findings of infection (such as high fever, tachycardia, leukocytosis, high CRP) * Presence of hematological or coagulation disorders * History or presence of cancer treatment * History or presence of connective tissue disease * Presence of diabetes * Being under 18 years of age will be considered as exclusion criteria.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Manisa Celal Bayar University
Manisa, Turkey (Türkiye)
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